In pictures: Michael Douglas and Catherine Zeta Jones

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Handout photo of Catherine Zeta Jones and Michael Douglas, attend a fundraising dinner in aid of the NSPCC Cymru/Wales Full Stop Appeal, for which Catherine is an ambassador, in Cardiff, Wales. PRESS ASSOCIATION Photo. Picture date: Monday June 19, 2006. See PA Story SHOWBIZ Hospital NSPCC Photo credit should read: PA
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Catherine Zeta Jones and Michael Douglas are "taking some time apart" to "work on their marriage", according to a statement released by her publicist. This 2006 picture shows the couple at a fundraising dinner in aid of the NSPCC Cymru/Wales Full Stop Appeal in Cardiff, Wales.

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Douglas, 68, and Zeta-Jones, 43, married in Manhattan in November 2000 after meeting in France in 1998. This picture shows the engaged couple posing for photographers outside the Russian Tea Room in New York.

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The couple had announced their engagement in January 2000, ending months of speculation. Douglas, who had spent Christmas with the actress in Wales, revealed that he popped the question as the couple celebrated the dawn of the new millennium at his home in the Rockies.

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Newlyweds: Michael Douglas with Catherine Zeta Jones on the island of Mallorca, Spain in May 2001.

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In one of her earliest TV roles, Zeta Jones appeared in the 1991 TV play Out Of the Blue, alongside Colin Firth.

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She went on to achieve TV stardom as Mariette in The Darling Buds of May (1991–1993).

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In the late 1990s, Zeta Jones made her name in Hollywood movies such as The Mask of Zorro and Entrapment. This 1999 shot, taken in New York, was taken to promote the latter, in which she co-stared with Sean Connery.

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In one of his earliest film roles, Michael Douglas played Adam Gaines, a professor of semantics, in the 1970 film Adam at Six AM.

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The star won an Oscar in 1988 for his portrayal of ruthless corporate raider Gordon Gekko in Wall Street. He reprised the character, famous for the line "greed is good", in a 2010 sequel: Money Never Sleeps.

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Zeta Jones won her Oscar, for best supporting actress, in 2003 after playing scheming showgirl Velma Kelly in the musical Chicago. The star, who was heavily pregnant at the awards ceremony, is pictured next to Nicole Kidman, who won best actress for The Hours.

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Zeta Jones getting windswept in St Andrews, Scotland in 2006 after her husband collected an honorary degree from St Andrew's University for his contribution to British film.

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The couple are pictured with their children, Dylan and Carys, at Buckingham Palace in 2011 where the actress was made a CBE by the Prince of Wales.

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The couple were photographed together on the red carpet at this year's Oscars at the Dolby Theatre, in Los Angeles. Zeta Jones recreated her Chicago routine during the ceremony.

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Michael Douglas took to the red carpet to promote Behind the Candelabra, in which he starred as flamboyant pianist Liberace, at the Cannes Film Festival in May 2013.

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Catherine Zeta Jones at the premiere of action movie Red 2 in Los Angeles in July. She had not been photographed with Douglas since April.