Pregnancy - the 'miracle' cure?

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Elizabeth Quigley with her son Matthew
Image caption,

Elizabeth Quigley's symptoms eased when she was pregnant with Matthew

It seems almost too good to be true.

Pain disappears, mobility returns and distressing symptoms disappear. No drugs, no medication and no painful injections.

For some women, the suffering of seemingly incurable conditions such as arthritis and multiple sclerosis just seems to disappear.

And what is this miracle "cure"?

Pregnancy.

I know this happens, because it happened to me.

I was diagnosed with MS in 2000. Before I became pregnant with Matthew in 2010, my walking was becoming more difficult. I used a stick for balance at the very least.

I was not able to write or use the keyboard very well. But then, during pregnancy, lots of those things changed.

It became easier to walk. I could write legibly again and type on a keyboard. The tremor on my hands almost disappeared.

I also seemed to get stronger, carrying things was easier and, incredibly, I could even lift my baby son for about the first nine months, something I thought would be impossible.

I knew this might happen, but I didn't know why. And I didn't know it happened across a wide range of medical conditions until I began working on a BBC Radio Scotland investigation.

I've been trying to find out just what it is about pregnancy that causes all these symptoms to disappear and whether this quirk of nature could really be turned into the reality of a treatment.

Walking with stick

During pregnancy oestrogen and progesterone levels rise to support the growing baby and to prevent a women's body from rejecting it. More than one hundred "autoimmune" diseases.

• Autoimmune diseases occur when the immune system wrongly attacks some of its own cells.

• Doctors say women suffering with at least one autoimmune disease, Lupus, can see their symptoms deteriorate in pregnancy.

The hormones suppress the immune system and also produce natural steroids to help support the baby.

It is not known exactly which of these factors is responsible for the dramatic improvement in the mothers' symptoms.

However for many women, after the birth, their symptoms deteriorate rapidly, which often causes an episode of deterioration known as a "relapse" in women with MS.

Two clinical trials - in France and the US - are looking at whether mothers given oestrogen or progesterone in the months immediately after childbirth can avoid these relapses.

Another study, run by the Belgium MS Society, found that women who were pregnant at least twice, experienced a slower rate of disability than those who were pregnant only once or had never been pregnant.

The society asked 973 women their experiences of disability with MS and whether they had been pregnant.

They looked at how long it took the women to reach a recognised "milestone" of MS - of walking with a stick - and found that those who had been pregnant at least twice were less likely to have reached this milestone.

However, the medical experts co-ordinating the study pointed out that it was difficult to tell whether the women felt better in the first place, and so became pregnant more than once, or whether the pregnancies themselves had this effect.

The lifting of symptoms definitely does not happen to all women with these health conditions who become pregnant but it does happen to some.

Unfortunately the downside of this temporary relief is that the health condition does return - and can often return with a vengeance.

But my discoveries certainly showed it was not just me and it was not just women with MS.

This strange quirk of nature seems to me to be a fruitful area for more investigation.

BBC Radio Scotland Investigates The Miracle of Pregnancy? will be broadcast on Sunday May 27, at 16:30.

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