AC Milan 0-1 Roma: Gianluca Mancini header gives visitors quarter-final advantage
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Gianluca Mancini also scored the winning header in Roma's derby victory over Lazio on Saturday
Gianluca Mancini's header sealed a 1-0 win for Roma over AC Milan in the Europa League quarter-final first leg at the San Siro.
The defender netted from Paulo Dybala's corner after 17 minutes, giving last year's runners-up an edge going into next week's second leg in Rome.
Olivier Giroud hit the woodwork late on but Milan could not find a way past Roma, whom they beat twice in Serie A.
Roma are bidding to reach a third successive European final.
Giallorossi boss Daniele de Rossi's reign began following a 3-1 loss at Milan in January, after which Jose Mourinho was dismissed - and Roma have lost only twice in all competitions since.
The winner of the all-Italian tie will face either West Ham or Bayer Leverkusen in the last four, with Xabi Alonso's side 2-0 up after the first leg.
Roma won the 2021-22 Europa Conference League and lost last year's Europa League final to Sevilla.