Lions head coach Ivan van Rooyen said: “Ospreys have been going really well. Their attack is very good and their defence is probably the most improved in the competition.
“We really want to put in a big performance especially here at home. Looking at our roster in the next few weeks and the number of tough games coming up, it’s important for us to put up a good performance this week heading into a packed schedule of local URC derbies.”
Ospreys head coach Toby Booth said: "The Lions play a slightly different game when they're at home.
"They have a stronger understanding of the conditions which they'll use to their advantage, especially in the kicking game.
"Often games like this one are about whether you can deal with the environment and whether you can adapt quickly, that will be the challenge."
Ospreys have made four personnel changes from the win against Perpignan.
Rhys Henry comes in at loose-head prop, Reuben Morgan-Williams returns at scrum-half with Will Hickey and Harri Deaves coming into the back row.
James Ratti switches from flanker to lock.
Wales' Six Nations squad members Adam Beard, George North and Owen Watkin are included, while Gareth Thomas missed out with a minor leg injury.
Springbok Ruan Dreyer returns to the Lions squad after recovering from a wrist injury, while Kade Wolhuter is in line for his debut from the bench.
Also returning to the squad is scrum-half Morne van den after completing his concussion protocol.
The teams in full:
Lions: Quan Horn; Richard Kriel, Henco van Wyk, Marius Louw (capt) Edwill van der Merwe; Gianni Lombard, Sanele Nohamba; JP Smith, PJ Botha, Asenathi Ntlabakanye, Ruben Schoeman, Reinhard Nothnagel, JC Pretorius, Emmanuel Tshituka, Francke Horn.
Replacements: Jaco Visagie, Morgan Naude, Ruan Dreyer, Darrien Landsberg, Hanru Sirgel, Morne van den Berg, Kade Wolhuter, Erich Cronje.
Ospreys: Iestyn Hopkins; Mat Protheroe, George North, Owen Watkin, Keelan Giles; Dan Edwards, Reuben Morgan-Williams; Rhys Henry, Sam Parry, Tom Botha, James Ratti, Adam Beard (capt), Will Hickey, Harri Deaves, Morgan Morse.
Replacements: Ethan Lewis, Cam Jones, Ben Warren, Lewis Jones, Tristan Davies, Cameron Jones, Jack Walsh, Keiran Williams.
Hello and welcome!
Lions v Ospreys KO 13:00 GMT
Getty ImagesCopyright: Getty Images
Good afternoon and welcome to our live text coverage of Ospreys' Challenge Cup trip to Johannesburg where they take on Lions.
Both sides go into this final Pool 2 match knowing they have qualified for the knockout stages.
Lions are currently third place with Ospreys in fourth - but victory at Ellis Park would boost Ospreys' hopes of a home tie in the last 16.
Kick off is on the way, so first let's take a look at the teams.
Live Reporting
Ceri Coleman-Phillips and Gareth Griffiths
All times stated are UK
Post update
Lions 3-0 Ospreys
George North took a big hit to the shoulder there, Ospreys and Warren Gatland will be keeping everything crossed it's just a stinger!
What do Ospreys need?
Lions v Ospreys KO 13:00 GMT
So to hopefully save you all the head scratching, here's what Ospreys need to secure a home tie in the next round.
A bonus-point win by 43 points or more puts them as 5th seeds and a home tie.
Victory (without a bonus point) would make them seventh seeds and a home tie against stronger opposition.
Anything less than a win and they're hitting the road for the last 16.
Simple.
Penalty: Lions 3-0 Ospreys
Sanele Nohamba
Lions score the first points of the afternoon, Sanele Nohamba is on target from the tee after Ospreys were off feet.
Missed penalty
Lions 0-0 Ospreys
Dan Edwards misses the opportunity to put Ospreys ahead after Lions were penalised for slowing the ball down.
Sin-bin - PJ Botha
Lions 0-0 Ospreys
It's an early yellow card for Lions.
PJ Botha has been sent to the sin bin for leading with the elbow when going into contact with Harri Deaves.
Can Ospreys take advantage?
Post update
Ellis Park is a 60,000 plus capacity stadium and it looks double that when it's empty - as it is today.
Post update
Lions 0-0 Ospreys
It's an early driving maul for Lions, the forwards make good ground before the ball is released and knocked on by JP Smith.
Kick-off
Lions 0-0 Ospreys
Jeremy Rozier blows his whistle and Gianni Lombard gets us under way at Ellis Park.
How the other regions fared
Lions v Ospreys KO 13:00 GMT
Scarlets and Cardiff have both bowed out of Europe.
Scarlets were beaten 31-19 by Edinburgh on Friday night, meaning Dwayne Peel's side finished pointless and bottom of Pool 3 in the Challenge Cup.
They also became the first Welsh region to not earn a single pool point.
Cardiff also suffered a heavy defeat in their final Champions Cup pool game.
They were beaten 48-26 at Racing 92, meaning Matt Sherratt's side finished bottom of Pool 2.
It was a seventh successive defeat in the Champions Cup for Cardiff on the pitch and the first time Cardiff suffered that record in 20 years.
Dragons host Sharks in the second of our live text coverage games this afternoon.
They still have hopes of making the Challenge Cup last-16.
They know victory at Rodney Parade will guarantee their place, possibly with a home tie if other results go their way.
Views from the camps
Lions v Ospreys KO 13:00 GMT
Lions head coach Ivan van Rooyen said: “Ospreys have been going really well. Their attack is very good and their defence is probably the most improved in the competition.
“We really want to put in a big performance especially here at home. Looking at our roster in the next few weeks and the number of tough games coming up, it’s important for us to put up a good performance this week heading into a packed schedule of local URC derbies.”
Ospreys head coach Toby Booth said: "The Lions play a slightly different game when they're at home.
"They have a stronger understanding of the conditions which they'll use to their advantage, especially in the kicking game.
"Often games like this one are about whether you can deal with the environment and whether you can adapt quickly, that will be the challenge."
Ospreys make four changes
Lions v Ospreys KO 13:00 GMT
Ospreys have made four personnel changes from the win against Perpignan.
Rhys Henry comes in at loose-head prop, Reuben Morgan-Williams returns at scrum-half with Will Hickey and Harri Deaves coming into the back row.
James Ratti switches from flanker to lock.
Wales' Six Nations squad members Adam Beard, George North and Owen Watkin are included, while Gareth Thomas missed out with a minor leg injury.
Springbok Ruan Dreyer returns to the Lions squad after recovering from a wrist injury, while Kade Wolhuter is in line for his debut from the bench.
Also returning to the squad is scrum-half Morne van den after completing his concussion protocol.
The teams in full:
Lions: Quan Horn; Richard Kriel, Henco van Wyk, Marius Louw (capt) Edwill van der Merwe; Gianni Lombard, Sanele Nohamba; JP Smith, PJ Botha, Asenathi Ntlabakanye, Ruben Schoeman, Reinhard Nothnagel, JC Pretorius, Emmanuel Tshituka, Francke Horn.
Replacements: Jaco Visagie, Morgan Naude, Ruan Dreyer, Darrien Landsberg, Hanru Sirgel, Morne van den Berg, Kade Wolhuter, Erich Cronje.
Ospreys: Iestyn Hopkins; Mat Protheroe, George North, Owen Watkin, Keelan Giles; Dan Edwards, Reuben Morgan-Williams; Rhys Henry, Sam Parry, Tom Botha, James Ratti, Adam Beard (capt), Will Hickey, Harri Deaves, Morgan Morse.
Replacements: Ethan Lewis, Cam Jones, Ben Warren, Lewis Jones, Tristan Davies, Cameron Jones, Jack Walsh, Keiran Williams.
Hello and welcome!
Lions v Ospreys KO 13:00 GMT
Good afternoon and welcome to our live text coverage of Ospreys' Challenge Cup trip to Johannesburg where they take on Lions.
Both sides go into this final Pool 2 match knowing they have qualified for the knockout stages.
Lions are currently third place with Ospreys in fourth - but victory at Ellis Park would boost Ospreys' hopes of a home tie in the last 16.
Kick off is on the way, so first let's take a look at the teams.