Image source, Getty Images

Donald Trump's doctor says the president has had no Covid-19 symptoms for 24 hours and has been fever-free for more than four days.

Sean Conley said Trump also had "detectable levels of Covid antibodies" and had not needed any supplemental oxygen since he was taken to hospital on Friday.

"His physical exam and vital signs, including oxygen saturation and respiratory rate, all remain stable and in normal range," a statement from Dr Conley said.

President Trump was discharged from hospital on Monday.

Read our full report here

Image source, Reuters

Alongside tonight's debate, the US headlines are still dominated by the White House coronavirus outbreak, which is continuing to spread around those in regular contact with President Trump.

White House adviser Stephen Miller and Coast Guard official Admiral Charles Ray are the latest to announce they are infected. Nearly all members of the Joint Chiefs of Staff are in quarantine after attending meetings with Adm Ray last week, the BBC's US partner CBS News reports.

In other news:

• Two alleged Islamic State suspects - dubbed "the Beatles" because of their British accents - have been charged in the US with terrorism offences over the killing of four US hostages

• President Trump has said he is ending negotiations over a Covid-19 relief bill and will only resume talks after the election. The move would have pumped stimulus into the economy as unemployment continues to rise because of the pandemic.

Anthony Zurcher
BBC North America reporter

Covid-19, and the Trump administration's handling of it, will clearly be the dominant topic of discussion. Mike Pence is in charge of the presidential task force on the pandemic, and he will be pressed to defend the administration's response.

Kamala Harris will probably be asked about her record on criminal justice as attorney general of California, as well as her shifting positions on healthcare reform. She ran to the left of Joe Biden during the race for the presidential nomination, so Pence's debate success may hinge on how well he is able to pin her more liberal views to Biden.

Finally, four years from now, Pence and Harris could be leading their party's tickets in the general election, so consider this debate a possible sneak preview of political battles to come.

Biden's pick breaks barriers as she's the first black and Asian-American woman on a presidential ticket. But Harris is a force in her own right. A senator since 2017, she's a former prosecutor and state attorney general - well known for her aggressive questioning style.

Image source, Getty Images

Measures have been stepped up since the presidential debate and plexiglass dividers will be in place between the two candidates. They will also be 12ft (3.6m) apart and they will be distanced from the moderator.

Pence’s chief-of-staff, Marc Short, had questioned the need for plexiglass, given the other measures in place, but Ms Harris’s team welcomed it.

Guests and candidates will all undergo testing beforehand and anyone who does not wear a mask will be "escorted out", according to the organisers, the Commission on Presidential Debates.

This follows concern after the first presidential debate when several members of Mr Trump's family sat in the audience without wearing masks.

Image source, Getty Images

The venue for Wednesday's 90-minute debate is Kingsbury Hall, at the University of Utah in Salt Lake City, and the moderator will be Susan Page, Washington bureau chief of USA Today.

Ms Page's question topics will not be announced ahead of time - unlike in the presidential debate. There will be nine segments of about 10 minutes each and both candidates will have two minutes to respond.

The rest of the time will be used by the moderator to coax a deeper discussion on the issue.

No opening or closing statements will be allowed.

It's being billed as the "most important vice-presidential debate in history, external". A few hours from now, the Democratic senator for California Kamala Harris will take to the stage with Vice-President Mike Pence with the country in the grip of a coronavirus pandemic that has reached all the way to the White House.

That President Trump himself has Covid-19 has reminded Americans that the vice-president is just a heartbeat away from the presidency, next in line to the most powerful political office in the world.

So while we don't know what will happen on stage tonight, it's a fair bet that voters will be looking for signs that Pence and Harris have the right stuff to take over if needed - and can be more presidential than the would-be presidents were at their debate last week.

Stay with us for all the build-up, and watch the debate live on this page. We'll bring you breaking news as it happens, views from ordinary Americans and all the context and analysis you need from the BBC's expert correspondents in the US and around the world.