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Conservative MP Claire Perry says Brexit will be a monumental process and, in an unusual analogy, likens it to studying for A-levels.

She tells the BBC "thank God we have a woman in charge" at this time. 

But UKIP's Douglas Carswell says the country has become "ossified" as part of the EU and while stepping into the light, as he puts it, might feel intimidating, he says it will be a refreshing challenge and Remainers need to play "catch-up".

The former Conservative, who says he has been campaigning to leave Europe his entire 4,327 days in Parliament, says he supports Theresa May 100%. 

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Labour's Daniel Zeichner says his views align with the majority of voters in his Cambridge constituency.

He says he will continue to support the EU because of "the part it has played in keeping a fractious continent from falling out" and will oppose the bill.

Tory MP Sir Gerald Howarth intervenes to suggest that the euro has divided the continent and impoverished some EU nations - but Mr Zeichner rejects this.

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Ulster Unionist Party MP Tom Elliott rejects suggestions that leaving the EU is "an act of madness by this House".

It was decided by a vote of the people, he says.

The MP for Fermanagh and South Tyrone says his constituency is "bordered by four counties of the Republic of Ireland" so there needs to be "flexibility".

He says the right course lies in backing the bill and then hoping that "negotiators will do their best for the United Kingdom" with Parliament keeping up "pressure" on them.

The UK's former ambassador to the EU tells MPs the negotiations will involve "difficult trade-offs".

Jeremy Corbyn attacks Theresa May over her response to the controversial US migration crackdown.

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Two MPs whose constituencies backed leaving the EU announce they will vote in opposite ways on the bill.

While a majority of voters in the Rhondda backed leave, the Labour MP for the area, Chris Bryant, says he cannot vote for the bill - and insists that he is acting with his constituents' best interests in mind.

"Not in my name," he says. "Never, never, never."

But Conservative MP Amanda Solloway tells the House that 57% of voters in Derby backing leaving the EU and she will vote in line with their wishes.

"Now is the time to come together and not be divided on this decision," she says.

Madeleine Moon and Kevin Brennan join the ranks of Labour MPs who will vote against the Brexit bill.

UK ministers want to devolve "as much as possible" when powers are handed back from the EU after Brexit, the Welsh secretary says.

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The guillotine comes down a little. Speakers in the debate now only have three minutes, as opposed to four, to make their points, John Bercow says.

That's going to be hard as plenty of members were already getting cut off in their stride. 

However, Cornwall MP Scott Mann shows how it is done by winding up his pro-Brexit contribution easily within the time limit.

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"My constituency voted to remain," says Chi Onwurah, the Labour MP for Newcastle Upon Tyne Central. "My country voted to leave."

For the second reason, she says she will vote in favour of the bill but argues that the government needs to accept amendments at later stages.

The leave vote was not a vote to leave the single market, Ms Onwurah claims and accuses Theresa May of "a constitutional land grab".

She continues: "When I talk to businesses they are incandescent that Tories are rejecting the greatest free trade alliance on the planet."

And the Labour MP adds that she has "zero confidence" in the government's ability to negotiate trade deals.

Labour's Kevin Brennan has just announced that he will vote against Article 50 - that's another MP defying Jeremy Corbyn. 

He is a shadow arts minister - a job he will, presumably, soon have to vacate. 

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"For centuries, Dover has had an important role as the gateway and the guardian to the kingdom," says the town's Conservative MP, Charlie Elphicke.

"People knew what they voted for and they made a clear decision," he says, indicating he will vote in favour of the bill.

He accuses Liberal Democrat leader Tim Farron of regarding the EU "like Hotel California: you can check out but you can never leave".

He adds: "The SNP seem to think that you should just have multiple referendums until you get the right result."

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The only ability we have to make these decisions in the House is that our constituents gave us this power at the election, says Labour's Tulip Siddiq, who resigned her shadow ministerial role in order to defy the Labour whip and vote against the bill.

The two main reasons Ms Siddiq is voting against the bill, she explains, is due to the lack of access to the single market, and for the future of the 17,000 EU nationals who live in her north London seat, noting that it isn't for electoral reasons, because they are not able to vote for her.

"The reason why I'm taking the stand I'm taking is because in Hampstead and Kilburn we do not wince when we hear people speaking different languages on public transport," she says.

"If I vote for this bill today, I am abandoning my responsibility to these EU nationals who live in my constituency."