Image source, HoC

Keir Starmer says says there are more than 400,000 people in the top priority groups identified by the prime minister, meaning they won't all be vaccinated next week.

He asks when people in the top two priority groups will get the jab.

In reply, Boris Johnson says the UK will roll out the vaccine "as fast as we possibly can" when millions of doses are delivered.

But he says it is important people "don't get their hopes up too soon" about the speed it can be rolled out.

Image source, HoC

Labour leader Sir Keir Starmer begins by welcoming the "fantastic" vaccine news.

"We're a big step closer to the end of the tunnel," he says.

He asks the PM who will be the first to receive the vaccine.

Boris Johnson says residents in care home, all those 80 years of age and older, and front line health care and social care workers will be among the first to get the vaccine.

Despite the good news he emphasises that it is still important for the public to follow Covid restrictions.

Read our full report here on who will get the Covid vaccine first?

Image source, HoC

Boris Johnson starts by saying the UK will publish its new strategy for disabled people next year.

The PM then hails the "fantastic" news that the Pfizer-BioNTech Covid vaccine has been approved and will be rolled out.

He thanks all those involved saying safe vaccinations will allow people to "reclaim their lives and get our economy moving".

In response to the first question from Tory MP Chris Green, the PM says he would strongly urge people to get the jab but insists it will not be mandatory, saying that is "not part of our culture or ambition".

Image source, HoC

House of Commons Speaker Sir Lindsay Hoyle gets to his feet to announce the beginning of Prime Minister's Questions.

Stick with us for updates as Boris Johnson takes questions from MPs.

Helen Catt
Political correspondent

This could be a much less difficult PMQs for Boris Johnson than it might have been.

He comes to the dispatch box off the back of the biggest rebellion yet under his leadership but the speedy approval of the Pfizer vaccine for UK use is a big boost.

It allows him to fight off Labour claims that the government has been on the back foot throughout the pandemic and offers hope of a way out.

Expect him to poke at Labour over their decision to abstain on yesterday's vote on England's new three-tier system.

Sir Keir Starmer though is likely to push hard on the economic damage of the pandemic and how the government plans to fix that.

He's also likely to press for the publication of a government document which spells out which sectors are suffering the most.

Image source, Reuters

The prime minister left No 10 Downing Street a few moments ago to head over to parliament for this week's PMQs.... our cue to standby.

Laura Kuenssberg
Political editor

The most important impact of Tuesday's vote is, of course, in the real world, with England being carved up into three different tiers to try to manage coronavirus.

But it was a notable political moment too.

If the opposition parties had also voted against the government, the prime minister's plan - and his central mission right now in government - would have been sunk.

He'd have been defeated, the proposals kaput.

Read more from Laura on last night's vote.

Image source, PA Media

Another topic which is bound to come up later is the new stricter Covid tiers system for England, which came into force today.

MPs approved the new system yesterday following a six-hour debate in the House of Commons.

But Boris Johnson suffered the biggest rebellion of his premiership, with 55 Tories voting against and a further 16 abstaining.

Sir Keir Starmer also saw 15 Labour MPs defy his instructions to abstain in the vote by voting against too.

The tiers will be reviewed in two weeks' time, whilst MPs have been promised a vote on renewing the system in late January.

At Downing Street this morning, a media briefing was held with three prominent people involved in the approval of the Pfizer vaccine.

Here's the priority list they outlined in detail:

Image source, Downing Street

Image source, EPA

Today’s session comes hot on the heels of the big news this morning that the Pfizer/BioNTech vaccine has been approved by UK regulators.

Health Secretary Matt Hancock said earlier that the first 800,000 doses will be available in the UK from next week.

Elderly people in care homes and care home staff will be the first to get it, according to a priority list unveiled this morning.

Yesterday, Boris Johnson said ministers could not "move too quickly" to end restrictions before a working vaccine is available.

BBC Politics

Image source, PA Media

Hello.

Welcome to our live rolling coverage of this week's PMQs.

We'll bring you all the details, with analysis from our political correspondent Helen Catt, external.

Thanks for joining us.