A day of calls from many Conservatives for Theresa May to quit as PM ends with a cabinet departure
Commons leader Andrea Leadsom quits her post, saying she no longer believes the government's approach will deliver Brexit
The prime minister tells Mrs Leadsom she is sorry to lose someone of her "passion, drive and sincerity in this way"
Mrs May had earlier set out her plan for a "new Brexit deal" designed to unite MPs
But it has been met with criticism from all sides
Labour, the SNP, DUP and Lib Dems have all said they won't back it
Tory Brexiteers are particularly angry at the offer of another referendum contained in the bill
Former Welsh Secretary Stephen Crabb says a new prime minister needs to take over within weeks.
Mr Crabb - previously loyal to Mrs May - told BBC Wales his party had "come to the end of the road with this prime minister".
"We are at a moment where we do need to turn a page and look at a new prime minister coming in the next few weeks." he said.
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A bit more from Brexiteer Steve Baker.
"It's all highly, highly undesirable," he admits, "but people shouldn't be under any illusions - this isn't personal. It's about the future of the country."
He says his party "needs to reassemble a governing coalition willing to take us out of the EU", under a new leader.
If that can't be done, there will be a general election and the Conservative Party "will be obliterated", he says.
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Conservative MP and leading Brexiteer Steve Baker reacts to the latest developments.
He says "the prime minister will be campaigning for the European elections and on Friday she will meet Sir Graham [Brady].
"Obviously, they will discuss matters of interest.
"It's very much going to depend on the result of the elections and I'm sure (the media) will be able to give us a flavour.
"People are rather impatient, but equally most colleagues do appreciate this is a very difficult time for everyone."
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Laura Kuenssberg
BBC political editor
More and more Conservatives are saying publicly the prime minister will have to quit.
No. 10 is adamant nothing has changed - she will press on and try to get her Brexit deal through, but it feels like this government is almost in breakdown.
It is not clear at this moment that they will be able to hang on.
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"At the moment, I'm minded to support Michael Gove," says Conservative backbencher Tom Tugendhat.
"This is a hugely demanding task," but he says "we started this the wrong way round" as the UK has been trying to "build a bridge to the future without knowing what the future is".
"Sadly, the time has come," he states.
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