South African variant causes concern over vaccine efficacypublished at 17:45 Greenwich Mean Time 4 January 2021
Andrew Harding
BBC News, Johannesburg
For weeks now, South Africa has been wrestling with an aggressive new wave of Covid-19.
The virus here has mutated to make it much more transmissible – very much like the British variant.
So far there’s no evidence that the virus has become deadlier. But scientists in South Africa are now racing to establish whether the mutations may have affected the virus’s ability to resist current vaccines.
There’s no hard evidence either way yet. But the concern arises from the fact that the virus here has mutated more than the one in Britain, and one of those mutations is linked to its ability to connect to antibodies.
Vaccines teach the body to mount an immune response - which includes creating antibodies - to fight the coronavirus, should it ever encounter it.
Antibodies are small proteins made by the immune system that stick to the surface of viruses, effectively disabling them.
If that ability to connect is weakened, then the antibodies created following the introduction of a vaccine might not be as effective.
Experts here are carrying out urgent tests and say they should know if that’s an issue within a matter of weeks.
But they also point out that it should be relatively quick and easy to adjust the vaccines. What’s more, they say, the current vaccines would still have some effect in neutralising South Africa’s variant of Covid-19.