Barcelona remain unbeaten in their five meetings with Napoli in all competitions, alternating between a draw (3) and a win (2) each time.

Both teams have scored in all five of the previous meetings between Barcelona and Napoli in all competitions, with Barcelona winning 4-2 and 3-1, as well as three 1-1 draws.

When Barcelona have avoided defeat away from home in the first leg of a UEFA Champions League knockout stage tie, they’ve progressed to the next round on 20 out of 21 occasions. The only exception was in their first such instance, drawing 1-1 at Juventus in the 2002-03 quarter-final before losing 2-1 at home (in extra time).

Napoli have been eliminated on each of the previous 11 occasions they’ve failed to win the first leg of a major European competition knockout stage tie at home. The most recent such instance was against Barcelona in the 2019-20 UEFA Champions League, drawing 1-1 at home before losing 3-1 away.

Barcelona have failed to win any of their last four UEFA Champions League knockout stage matches (D2 L2), since beating Napoli 3-1 in the second leg of the 2019-20 round of 16. They’ve never gone five without a win in the knockout rounds of the competition before.

Napoli have won five of their eight UEFA Champions League away games since the start of last season (L3), as many as they had in their previous 21 on the road in the competition (D6 L10).

Barcelona’s Robert Lewandowski has been involved in 18 goals in his last 12 appearances in the knockout rounds of the UEFA Champions League, scoring 12 and assisting six. He’s also had a hand in 11 goals in his last 10 games against Italian sides in the competition (7 goals, 4 assists).

Victor Osimhen’s equaliser for Napoli in the first leg against Barcelona was his ninth UEFA Champions League goal, the joint-most by a Nigerian player in the history of the competition (level with Obafemi Martins).

In the first leg against Napoli, Barcelona’s Lamine Yamal became the youngest ever player to appear in a knockout stage game in the UEFA Champions League (16y 223d). Should he appear in this match, he could also become the first ever 16-year-old to score a goal in the competition.

Khvicha Kvaratskhelia has completed 61 dribbles in 16 appearances for Napoli in the UEFA Champions League, already the most by any player of the Italian side in their history in the competition. His per 90 average of 4.3 completed dribbles is more than twice as many as any other Napoli player to have played 900+ minutes in the competition (1.9 – Lorenzo Insigne).