Andre-Frank Zambo Anguissa celebrates scoring
Napoli moved three points clear at the top of Serie A with a narrow victory at Lecce.
David Neres' free-kick into the box was headed home by Andre-Frank Zambo Anguissa from close range in the 69th minute as Antonio Conte's side took the lead.
Leece had a chance to open the scoring after 57 minutes when Francesco Camarda stepped up from the spot but his penalty was well saved by Napoli goalkeeper Vanja Milinkovic-Savic.
The Serb has saved five of the past nine penalties he has faced in Serie A.
The result means Napoli move three points ahead of second-placed AC Milan.
It was Napoli's first game since Kevin de Bruyne suffered a significant thigh injury which will rule him out for a lengthy period.
The league headers host Como in their next league fixture on Saturday (17:00 GMT).
Later on Tuesday, AC Milan played out a 1-1 draw with Atalanta as they moved third, level on points with second-placed Roma.
Samuele Ricci's deflected strike from outside the box in the fourth minute put Milan in front.
However, their lead was cancelled out by Ademola Lookman who fired into the roof of the net in the 35th minute as the home side drew for the seventh time in nine league matches.
