Were you at the game or following from elsewhere?
Have your say on Southampton's performance
What did you make of Bournemouth's display?
Come back to this page on Monday to find a selection of your replies
Seven matches make up Saturday's Premier League action and BBC Sport will bring you every kick.
Leicester City v Arsenal (12:30)
Aston Villa v Ipswich Town
Fulham v Nottingham Forest
Man City v Newcastle - BBC Radio 5 Live commentary
Southampton v Bournemouth
West Ham v Brentford
Crystal Palace v Everton (17:30) - BBC Radio 5 Live commentary
All kick-off times 15:00 GMT unless stated
I'd be shocked if Bournemouth don't win this.
Even in the FA Cup against Burnley, Southampton could not give their home fans anything to cheer about. Dear me, what a depressing season this has been for them.
Saints would be better off finishing the campaign now - just packing up, shutting the ground down and looking forward to next season, or looking ahead to it, anyway - why would you be looking forward to it after such a dismal few months?
Bournemouth are well organised, have a good balance to their team and Justin Kluivert is on fire. They have quite a few injuries but you don't hear them complain do you? They just get on with it.
Sutton's prediction: 1-3
Millie Sian
BBC Sport journalist
Bournemouth boss Andoni Iraola has been speaking to the media before Saturday's Premier League game at Southampton (kick-off 15:00 GMT).
Here are the key lines from his news conference:
Alex Scott and Luis Sinisterra could return from injury this weekend. Both players are "expected to train in the final session" but it is not yet known if they will be named in the squad. He added: "I expect at least one of them to make the trip with us."
He praised his players for "performing very well and giving the level we thought they had" over the past two months, which he believes contributed to their 11-game unbeaten run.
Bournemouth are expecting "a very different game" to when they played Southampton at Vitality Stadium earlier this season: "The way they played under Russell Martin was a completely different approach. You can see what the new manager wants to do. He has this kind of system that a lot of Italian teams play, and it isn't easy to play against."
On the changes that Ivan Juric has made at Saints, Iraola added: "They press a lot off the ball. They go to man-mark and I don't expect us to be comfortable on the ball. We will do the same, so I think it's going to be a big fight in the middle. Their approach on the ball is much more direct now, especially to Paul Onuachu and other players up front."
More on the match against the fellow south coast side, who are battling relegation as the Cherries push for Europe: "It's a game our supporters want to win, for sure. It must be the same for them. The most important thing is the points, especially considering the standings."
When asked about being in a good position to secure European football for next season, Iraola replied: "We are not there yet. We would like to be there, not today but in two months when you are literally playing for the final standings. For now, we are just trying to add points."
He feels the Cherries have not had to "depend on one player or one striker" this season, despite Justin Kluivert scoring six goals in six games.
On the Dutch forward regularly being compared with his father, Patrick, he added: "He uses it in a positive way. It helps that his father is a coach and he understands the other side of the job. He uses his father's advice very well and he is very proud of him. I think he enjoys when we compare them. He doesn't see it in a way of adding more pressure, he focuses it in a proper way."
Follow all Friday's Premier League news conferences and the rest of the day's football news
Bournemouth, Newcastle United and Tottenham are all interested in signing 24-year-old Brazilian winger Igor Paixao from Feyenoord. (Sun), external
The Cherries are yet to open negotiations with manager Andoni Iraola, with the 42-year-old Spaniard set to enter the final year of his contract after the end of the current season. (Mail - subscription required), external
Image source, Getty ImagesWe asked for your views on what's the one thing no-one is talking about at Bournemouth.
Here are some of your comments:
Mark: The fact that, given this season's league results and our current form, we could make a strong argument for being third favourites to win the FA Cup!
Ken: It's got to be the FA Cup. There has never been a better chance. If Andoni Iraola takes it seriously, it can happen.
John: It has been a really good season to date. They are doing exactly what I have been saying for a couple of seasons now, upping their all-round fitness levels so they can press and retreat without getting too tired and not playing Philip Billing regularly who was the weak link. Even selling Dom Solanke hasn't changed the resolve Iraola has instilled into the squad. If they get into Europe, they will need to strengthen the squad as playing midweek abroad and league matches at the weekend will take its toll. Hopefully, they can keep players and add quality.
Bernard: A great time for us supporters as the players are doing us proud. However, what is not talked about is the great work being done by the backroom staff and scouts who continue to find little gems and bring them to the academy, thus assuring a healthy future - not just immediate but also for the long term.
Clive: The success of the women's team reflects the feel-good factor generated by the men's team. Bournemouth is a good place for players to learn and grow.
Image source, Getty ImagesBBC Sport pundit and former Manchester City defender Nedum Onuoha has been answering your questions on your club.
Abbass asked: Do you think Bournemouth will make European football at the end of season?
Nedum replied: That is a cracking question. I think because of the injuries they have, it feels like they are stretched to the point of having no significant cover. Yet the results are still falling their way.
It is the same for any team around them, in the sense that if they can carry on picking up points in this stage of the season where there is a sense of desperation with any team you meet, then they are in with a very good chance.
They have the ability to win games at home and on the road, while making teams feel really uncomfortable. It is tough to say.
It will also depend on the permutations of who wins competitions this season and whether extra European places will be available.
They could win the FA Cup, for example, and then they wouldn't need to depend on the Premier League or the winners of other European spots. Bournemouth should have the belief that they can go on and win that this season.
It is a credit to them, their club and the way it is run if they can book a place in a European competition because if you didn't have true stability or a desire to improve then they would never have given themselves this opportunity.
The season Liverpool won the Premier League was the year Bournemouth got relegated, and now here they are going toe to toe with some of the best teams in world football.
For a club their size, and because of the way they have progressed through the divisions over the years, it would be huge if they could do it. But if they don't then what an incredible season it has been so far for them.
Nedum Onuoha was speaking to BBC Sport's Katie Stafford
Image source, Getty ImagesBournemouth "need to develop" Vitality Stadium but any project must have the supporters in mind, says former Cherries defender Joe Partington.
Owner Bill Foley has spoken about his hopes of remaining on the Dean Court site, external rather than build an entirely new ground. The current stadium has a capacity of 11,307 - the smallest in the Premier League.
"I'm on the fence about it really," Partington told BBC Radio Solent's Cherries: Unpicked podcast. "It seems as if there will be progression in terms of the stadium but I would be inclined to stay at the current location.
"I've grown up with it - I think it's a wonderful location. It's easy to get to for supporters, there's a lot of history at that stadium and a lot of people who have supported the club for a long time will hold going there very close to their heart.
"Many clubs do it very well where they develop the existing stadiums they have. I wish I knew the ins and outs of construction but I just don't really understand how they are going to 'dig down'. I'm not sure what they'll do in the meantime about where they play.
"Developing the stadium would be amazing. The club has moved forward past the realms where the stadium is possible to sustain. The club does need to develop further to continue to push forward. But, how will that have a benefit on the matchday experience for the fans? If people have been waiting years to get a ticket will they be able to with new seats going to hospitality.
"The club is run by good people it seems and they have the supporters in their mind so hopefully there is an agreement everyone is happy with and fans can continue to come and support their team in more numbers than they are now."
Mark Mitchener
BBC Sport senior journalist
Image source, Getty ImagesHaving notched up their third victory over Everton this season in Saturday's FA Cup fourth-round tie, the draw has handed Bournemouth the chance for another 'three-peat' in the next month.
A quirk of the fixtures means Wolves will visit Vitality Stadium on two successive weekends - 22 February and sometime during the weekend of 1 March - though both teams do have league fixtures in the intervening midweek, with Bournemouth going to Brighton and Wolves hosting Fulham.
So there will be plenty of familiarity by the time that fifth-round tie comes around, but former Cherries player Joe Partington explained on BBC Radio Solent's latest Cherries: Unpicked podcast: "I can guarantee that both teams will make changes, although Bournemouth only made a couple of changes at Everton.
"No two games are the same. You think you learn something from the first game, but the second can be completely different.
"But I wouldn't underestimate Wolves. They are full of really good players who can hurt you, and they are capable of beating anyone.
"It's an exciting time. People are almost falling back in love with the FA Cup because of the upsets, like Plymouth beating Liverpool."
Before then, Bournemouth make the short trip to Southampton on Saturday for the derby that isn't a derby.
While the rail networks have perversely chosen this particular weekend to close the lines through the New Forest, Andoni Iraola's squad - and their supporters - will hit the roads in a reasonably confident manner, as they look to extend a sequence which has included only one defeat in their past 14 games.
Local pride (and rail replacement buses) aside, Iraola will be hoping for another professional performance to help them keep pace with the top six.
A 5-0 drubbing of European football chasing rivals Nottingham Forest, through to the fifth round of the FA Cup, sitting three points off the top four in the Premier League - despite a recent blip against league leaders Liverpool, there is a lot to be happy about for Bournemouth and their supporters right now.
But Cherries fans, you know your club best - so we need you to tell us the one thing that no-one is talking about at Bournemouth but really should be?
Image source, Getty ImagesFormer Bournemouth defender Joe Partington says Daniel Jebbison "learned things about himself" during his loan at Watford that he can take into his Cherries career.
Striker Jebbison spent the first half of the season at the Hornets but struggled to make an impact in the Championship and was recalled in January, after injuries to Evanilson and Enes Unal, having not scored a goal.
However, he has now scored in the third and fourth rounds of the FA Cup and impressed in Sunday's win over Everton.
"Loans are so important for young players both positively and negatively," Partington told BBC Radio Solent's Cherries: Unpicked podcast.
"He went to Watford and for whatever reason didn't do very well. But, he learned things about himself, his game and his mentality that will help him in the long run for Bournemouth.
"Jebbison didn't set the world alight at Watford but that doesn't mean he won't be a good player for Bournemouth. It doesn't define your game or career. A negative loan can help strengthen your game.
"As a young player you're not given many opportunities, so when you get them you need to take them. There is a lot of pressure making appearances - because they might be your last if they don't go very well.
"What is nice is the manager has trusted him enough to give him an opportunity and he's performed well and scored. Does the manager trust him now a little bit more if he needs someone to come off the bench in the Premier League? Absolutely yes."
Image source, Getty ImagesFollowing their 3-1 win at Vitality Stadium in September, Bournemouth are looking to complete the league double over Southampton for the first time, in what is the 15th different campaign in which they have met.
Meanwhile, the Cherries have won possession in the final third more often than any other Premier League side this season (146), while Saints have lost the ball more often in their defensive third than any other team (154).
Image source, Getty ImagesThe latest episode of Cherries: Unpicked has landed.
Former Bournemouth defender Joe Partington joins BBC Radio Solent's Jordan Clark to analyse the FA Cup win against Everton.
The pair also discussed Bill Foley's plans to "dig down" on the existing footprint of Dean Court and "double-deck" the temporary south stand to increase the stadium's capacity.
Listen to the full episode on BBC Sounds
Arsenal, Chelsea and Liverpool are interested in 19-year-old Bournemouth defender Dean Huijsen, who has a £55m release clause in his contract. (TBR Football), external
Want more transfer news? Read Wednesday's full gossip column
Tom Jordan
Fan writer
Image source, Getty ImagesA break from the league campaign didn't stop Bournemouth's impressive run of form, with a comfortable victory and clean sheet on what was our final trip to Goodison Park.
A lot has been made of gaffer Andoni Iraola's aggressive and offensive approach, and rightly so, however it's equally pertinent to discuss the club's improvement in defence. While pundits openly laud the Cherries' tendency to play on the front foot, where we can be seen creating a host of chances in all but every fixture, this often overshadows our prowess at the other end of the pitch, where there has been a clear improvement in defence.
Despite key injuries to the backline, Bournemouth look just as hard to score against as they do hard to prevent scoring. Having lost their longest servant and skipper Adam Smith, as well as central defender Marcos Senesi for large parts of the campaign, it was a fear that the club would give up too many chances and goals, particularly with their brave and attacking approach to all games.
However, Lewis Cook has filled in at an unfamiliar full back position admirably, plus, young defender Dean Huijsen has been nothing short of a revelation.
In keeping with that, the loan signing of Kepa Arrizabalaga from Chelsea between the sticks has seemingly increased confidence and has calmed those in front of him.
As a defensive unit, the lads have been exceptional, and it certainly helps that those higher up the pitch are constantly breaking up the play and relieving pressure with their remarkable press and energy.
In all, both aspects of Bournemouth's game are at a high level at present. It could well mean a special season for the Cherries.
Find more from Tom Jordan at Back of the Net, external
Bournemouth defender Dean Huijsen is being monitored by Premier League rivals Chelsea. (Teamtalk), external
Want more transfer stories? Read Tuesday's full gossip column
The draw for the FA Cup fifth round has been made. Here is a list of all the ties involving Premier League teams in the order they were drawn.
Games will be played over the first weekend of March.
Aston Villa v Cardiff City
Crystal Palace/Doncaster v Millwall
Man Utd v Fulham
Newcastle v Brighton
Bournemouth v Wolves
Man City v Plymouth
Exeter/Nottingham Forest v Ipswich
Is there something you want to ask about a Premier League club?
Former Premier League defender Nedum Onuoha is ready to answer your burning questions and give his thoughts on some of the biggest talking points for a special Q&A.
Submit your questions here and come back on Thursday for his answers
We asked for your views on Eveton's match against Bournemouth in the FA Cup.
Here are some of your comments:
Everton fans
Greg: We were very poor in the first half though improved after the break. Tarkowski had a game to forget and cost us the two goals. Alcaraz looks like he may have something. I like the way he's positive in the way he plays. He should start on Wednesday instead of Doucoure who is fast going downhill.
Graham: Two bad mistakes from a usually reliable defender. We did everything but score in the second half. If they play like that for the rest of the Premier League games we will be OK.
Barry: Dreadful first half performance; much better second-half. Second goal gave us a mountain to climb against a well organised Bournemouth, who have become a real bogey team for us. Let's hope the second-half performance is taken into the derby on Wednesday, as Liverpool will make hay if we perform like we did in the first half. Will happily take the cup exit for a final Goodison derby win!
Bournemouth fans
Charl: Bournemouth deserve a lot of credit for this result. A competent defensive display, an assured midfield performance and two goals against an in-form team. Very well done Andoni and the squad.
Paul: A classic game of two halves. Totally dominant in the first half but couldn't control midfield the same way in the second. Solid defensive effort throughout though, and, unlike the Liverpool game, the woodwork helped us out this time. Onto the next round!
Sean: That was some penalty from Semenyo! First half Everton let us play our game and we took our chances. Everton had a second half purple patch but were wasteful. A deserved win and hoping for a favourable tie in the next round.
Image source, Getty ImagesBournemouth have gone seven consecutive away games without defeat in all competitions for the first time since January-March 2016 (also seven). The Cherries have also reached the fifth round of the FA Cup in consecutive seasons for the first time in their history.
