Latest scores and resultspublished at 19:05 British Summer Time 14 October 2014
So Spain's era of dominance in world football is completely over now. The national team could not get out of their World Cup group in Brazil in the summer, and now their Under-21 team have failed to qualify for the European Championship in 2015.
They drew the first leg 0-0 in Serbia, but slumped to a 2-1 home defeat in the second leg.
The Spanish line-up included Liverpool full-back Javier Manquillo, Stoke midfielder Marc Muniesa, winger Gerard Deulofeu, who enjoyed a successful loan spell at Everton last year, and Real Madrid attacking midfielder Isco (pictured).
Elsewhere, Portugal won a thrilling second leg 5-4 to defeat Netherlands 7-4 on aggregate. Germany beat Ukraine 3-0 in the second leg, to seal a convincing 5-0 aggregate success. Iceland and Denmark are currently goalless, and could be heading into extra-time.