Postpublished at 22:45 Greenwich Mean Time 3 February 2015
That's the end of the night's action here.
Check out our FA Cup index for all of the goals and highlights, and we'll see you for Bolton v Liverpool tomorrow.
Man Utd ease into fifth round
They will face Preston, who beat Sheff Utd
Sunderland win 3-1 at Fulham
Black Cats face Bradford next
Watch best moments via highlights tab
Tom Rostance
That's the end of the night's action here.
Check out our FA Cup index for all of the goals and highlights, and we'll see you for Bolton v Liverpool tomorrow.
The final word of the night from BBC Cambridge reporter Sam Edwards., external He travelled up to Manchester in a supporters' coach, only for it to break down around 18:00 GMT on the M6 motorway. He arrived at Old Trafford with only half an hour left, after a Warrington coach company heeded his panicked calls for help.
Now, with the game over and done with, Sam seem philosophical:
@edwardssport:, external Thanks for the messages. I'm lucky enough to be working and in a car on way home. Feel for fans who booked days off and on coach back.
So do we, Sam. So do we.
BBC Radio 5 live
Sunderland manager Gus Poyet on 5 live Sport: "We played well the the first half, really aggressive and high. We were in control and I was happy with our performance, and I'm happy with the final result. Today my players enjoyed playing their football. That was one of the first games this season that I've been really happy, watching my team play."
BBC Radio 5 live
Preston manager Simon Grayson on 5 live Sport: "It's been a disappointing few weeks for us but tonight is an excellent result. We've been lacking attacking options and confidence recently, but we're getting those players back now. But there was a massive incentive tonight to play Manchester United, and it brought out the best in us.
"We had to be focused tonight, because we know how good Sheffield United are. They have done fantastically well in the cups. We had to be at it, and from the first whistle we were really good and dominated, and they scored against the run of play. We kept our belief going.
"It's a massive result, and there was a massive carrot for us. Forget Manchester United, we just wanted to get back to winning ways. This result can hopefully now galvanise our league form.
"I'm sure it will be very difficult to get tickets for Deepdale, but I'll limit those I give out to people who came to places like Crawley and so on in January."
Apologies if I earlier said that Bradford will play Fulham in the next round - it is of course Sunderland! What a total idiot.
Manchester United boss Louis van Gaal talking to the BBC: "Cambridge have played very well, a very organised team and with the mentality that was superb. The fans were fantastic from Cambridge United. We have done what we had to.
"Every club in the FA Cup wants to win, we also. We have to beat Preston and that will not be easy, they won away against a cup fighter like Sheffield United, so it will be difficult for us to win in Preston North End.
"For the club, the fans and the coach and my staff, we want to win a title this year. The biggest chance is the FA Cup, but we still have to win four games to do that.
"Tonight, I don't think we played a very good match. But it is always difficult against a defensive team. We could have done better but I am pleased with the result."
Who are favourites to win the FA Cup now? Manchester United are the highest-ranked side still in the competition.
There is something magic about Louis van Gaal's pronunciation of 'Preston North End'. Wonderful.
Crystal Palace v Liverpool or Bolton Wanderers
Arsenal v Middlesbrough
Aston Villa v Leicester City
West Brom v West Ham
Bradford City v Sunderland
Blackburn Rovers v Stoke City
Derby County v Reading
Preston North End v Manchester Utd
The replay between Liverpool and Bolton is live on BBC One tomorrow night.
Cambridge manager Richard Money: "I was really pleased with them second half. To come in 2-0 down and play with purpose and control is not easy but we did that.
"We gave the ball away too cheaply in the first half. But I couldn't fault them for their organisation and work ethic.
"I said at half time what's the worst that can happen. You get battered? But so what. So go and show what you can do.
"I'm not sure how many clear chances they really created. They caught us on the counter-attack but we wanted to get bodies up the pitch.
"I just wanted to get a goal for the fans. And I thought we had at the end."
Manchester United midfielder Marouane Fellaini: "It's important to win a trophy so we will try, we work hard for that. We are winning at the moment but we continue to work hard. The manager is the boss and decides where I must play.
"We win 3-0 which is good for confidence. We played well."
Jean Pelletier: Man Utd look good for Wembley this year.
Sam Burnett: Bit of a cakewalk in the end really, for Manchester United. The gulf in class was evident. Fair play to Cambridge though, they worked their backsides off.
Luke: Cambridge should be proud. Louis van Gaal was forced to select the strongest United side to better them. 3-0 over two legs? Not many can top that.
Get in touch on Twitter using #bbcfacup,, external text us on 81111 (UK only), or leave a message on the BBC Sport Facebook, external or Google+ page., external
Manchester United midfielder Juan Mata has been involved in 15 goals in 15 FA Cup appearances (scoring six, assisting nine).
Can he nail down a place in the first team though?
Former Preston winger Kevin Kilbane on social media
"Outstanding win for Preston tonight!"
A reminder that you can watch the goals from Old Trafford and Craven Cottage via the highlights tab at the top of the page. We'll also have full highlights of both games later.
BBC Sport's Simon Stone at Old Trafford: "Manchester United's performance can be analysed in numerous ways.
"On the negative side, a bizarre formation, strange early reliance on long balls up to Marouane Fellaini and far too many misplaced passes.
"On the positive, reliance on Fellaini paid off, and 24 hours after the departure of Darren Fletcher after almost 20 years at the club, eye-catching performances from two more home-grown youngsters, Paddy McNair and goalscorer James Wilson.
"Ultimately though, this competition is about being in it - and they are, with a trip to League One Preston standing between them and a quarter-final berth.
"As for Cambridge, they will be talking about the one that hit the post from Tom Elliott for years."
Give us a chance. There's no way we'll get David Beckham...
Blackburn Lad: Moyes as pundit for the Man Utd v Preston match? Yes please! Surely the Beeb can make it happen, can't it?
Thomas Fiorilli: Yes, I can think of a good pundit. One who played for both clubs and is a United legend. He scored the odd amazing free kick...
Red Malazan: Beckham should pundit the Preston game!
Get in touch on Twitter using #bbcfacup,, external text us on 81111 (UK only), or leave a message on the BBC Sport Facebook, external or Google+ page., external
A few Cambridge players have shirts from the Manchester United lads, but none of the amber shirts have been swapped. I forgot that they have been outlawed from doing so. Richard Money calls his players into a congratulatory huddle in front of the 6,000 away fans.
"Let's take this memory into the league and kick on..." he'll be saying. Or similar.
There it is, it's all over. Cambridge boss Richard Money salutes the fans as his players battle it out for the shirt swap.