Three defeats in four games for City means their impressive start to the season is a distant memory.

Spurs are on the up, though. This was their third straight league win and they have not lost in the league since the opening day of the season.

For a developing match report go here.

And for the rest of the reaction from White Hart Lane, and the team news and build-up for all the 15:00 BST games, you can go here.

Daniel Tinkler: Lamela told to buckle up and prove his worth by Pochettino and in the last 2 games has been on fire. So that worked then.

Luke Parsons: I think what we've seen today shows why English clubs struggle in Europe, none of the big teams have the squad depth to compete

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Joshua Bolaji on Twitter: No excuse for Manchester City about missing players, their back-ups are £30m players...please!

Jack Matthews: Anything West Ham can do, Spurs can do better.

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City are still top - for now. Spurs are up to fifth, again for now, but I don't think they will care too much if they drop a couple of places after that performance.

A reminder that City did not concede a single goal in their first five league games - without Vincent Kompany they have conceded six in their last two league matches... there might be a connection there...

This was a woeful defensive display by City all round - especially by goalkeeper Willy Caballero, who was at fault for Tottenham's second goal.

Jermaine Jenas
Former England midfielder on Final Score

"He's on the bench today, and if he has got an injury why wouldn't you leave him at home and have Richard Wright on the bench? 

"We'll find out on Wednesday against Borussia Monchengladbach."

The Spurs players are celebrating on the pitch. City's team disappeared down the tunnel as quickly as they could.

Jermaine Jenas
Former England midfielder on Final Score

"Three of the goals have been blatantly offside, but it's just the way the game goes sometimes. Spurs showed real character today and they've all turned up, Harry Kane has got his goal and they've taken their chances. After the derby defeat midweek by Arsenal this is exactly what they needed."

Image source, Getty Images

Spurs fans are giving it the "ole" after every pass, as we go into injury time at White Hart Lane.

City's defending without Vincent Kompany has been poor, and Joe Hart was badly missed in goal - as was David Silva in attack. These are worrying times for City, especially with an important Champions League game against Borussia Monchengladbach in Germany on Wednesday.

Maggie in Lowestoft on text:  Im in dreamland. So pleased for Kane and Lamela. No one gave us a prayer today. This will be huge for Spurs confidence and belief.

Chris in Banbury: Is Nasri really good enough to be in a side going for the Title and Champions League, there's a reason why he's not selected for France.

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City fans should probably make the most of seeing their side at the top of the table - United host bottom-side Sunderland at 3pm and will go above their neighbours with any sort of win.

Dele Alli goes into Mark Clattenburg's book for fouling Kevin De Bruyne. City have a free-kick near the left-hand corner of the area, which De Bruyne takes... but sees his shot easily saved by Hugo Lloris. The Spurs keeper has not had a very busy afternoon.

Raj on Twitter: Is a hammering at White Hart Lane part of becoming champions? happened to Chelsea last year.

Ben Garrett: Erik Lamela's best game in a Spurs shirt by a country mile.

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Image source, AP

Yep, Sergio Aguero makes way for Patrick Roberts. He has not had a particularly productive afternoon for City.

Spurs are making a change too. The impressive Erik Lamela is replaced by Tom Carroll.

Michael Phillips on Twitter: Spurs got a lucky break before half time but have capitalised on it. Been far the better side second half.

James Watson: Like tissue paper in water today Manchester City - not good enough!

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City are bringing on young forward Patrick Roberts for the final few minutes - for the experience rather than to salvage the result, I would presume.

Paul Gibbons on Twitter: Same old city of last season one bad result and they seem to mentally crumble for a few games

Charlie Platt: Pellegrini has quite a poor record in stopping one poor result for City spiralling into several in quick succession.

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Image source, Getty Images

White Hart Lane is bouncing now... except from the corner of the ground housing the away fans. It gets worse for City too - I'm told there were loud cheers at Old Trafford when that fourth Spurs goal went in - if the score stays the same then Manchester United will go top later, if they beat Sunderland.