Liverpool will be without captain Jordan Henderson, who is suspended after being sent off last weekend.

Boss Jurgen Klopp says a number of unnamed players are nursing knocks following the midweek defeat by Paris St-Germain.

Everton manager Marco Silva has no new injury worries ahead of his first Merseyside derby.

Ademola Lookman is in contention to make his first league start of the season.

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Jermaine Jenas
Former England midfielder on Radio 5 live

Anderson stood out like a sore thumb. He gave DeAndre Yedlin a torrid time. The quality he possesses is unbelievable. He’s not selfish as a player.

He is becoming one of those cult heroes that West Ham like in their ranks.

Sulaimon Adelekan: It's Derby day in the Premier league where form is out the window, emotions run high and all that matters is the result.

Danny Murphy
Former England midfielder on MOTD

It was an awful start, I’m not blaming tactics or Jose Mourinho, it was individual errors. Complacency, lack of concentration, call it what you want but you have a personal pride when you step onto the pitch.

As a professional playing for one of the biggest teams in the world you have to be ready. It's not acceptable, there were too many in the first half an hour, it was awful.

BBC Red Button

There isn't just one Merseyside derby taking place today.

Liverpool Women also take on Everton Ladies, while a huge clash between Manchester City and leaders Arsenal is going ahead.

You can listen to the derby on Radio 5 live sports extra from 11:55 GMT and watch Man City's match with Arsenal on the BBC Red Button, Connected TV and online from 12:20 GMT.

Danny Murphy
Former England midfielder on MOTD

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Palace’s season has been like that. They have played well, had lots of chances but not converted them. Again they didn’t, they had a lucky goal and a wonder goal.

Burnley gave nothing back, they were completely dominated. Andros Townsend’s goal was goal of the day.

Maurizio Sarri makes two changes to the side that were beaten by Tottenham last Saturday as Pedro and Olivier Giroud come in for Willian and Alvaro Morata drop to the bench.

It means there is a place for Eden Hazard in the starting XI, while Giroud will look to replicate his form from mid-week, when he struck twice in the win over PAOK Salonika.

Chelsea XI: Arrizabalaga; Azpilicueta, Rudiger, David Luiz, Alonso; Jorginho, Kante, Kovacic; Pedro, Hazard, Giroud.

Subs: Caballero, Christensen, Zappacosta, Fabregas, Loftus-Cheek, Willian, Morata.

Claudio Ranieri makes one change for his second match in charge at Fulham; as Stefan Johansen replaces Andre Schurrle, who does not make the matchday squad.

Aleksandar Mitrovic leads the line following his double in the defeat of Southampton last week, and midfielder Tom Cairney captains the side.

Fulham XI: Rico; Christie, Odoi, Mawson, Le Marchand; Seri, Chambers, Johansen, Cairney, Sessegnon; Mitrovic.

Subs: Bettinelli; Ream, Bryan, Kebano, Ayite, Cisse, Kamara.

Following yesterday's victory for Manchester City, anything other than a win for Liverpool will be disappointing given the five-point gap that will have been created.

Arsenal can also drop four points off the top four if Chelsea beat Fulham and they fail to avoid defeat against rivals Spurs.

Whatever happens, there's expected to be plenty of change at the top!

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Eden Hazard starts as Maurizio Sarri makes two changes to the Chelsea side which lost to Tottenham last weekend.

Fulham make just one change as Stefan Johansen comes in for Andre Schurrle, who doesn't even make the bench.

Full team news to come.

Manchester City moved five points clear at the top of the Premier League and Crystal Palace earned their first home win of the season.

But which English player created history and which strike ended a run of 981 minutes without a goal?

Here are the best of Saturday's Premier League stats...

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Jermaine Jenas
Former England midfielder on MOTD

There are some huge positives for Southampton. They started the game well. But you can’t help but feel they become very, very nervous. The start was brilliant. They were a lot stronger and resolute – even if they were doing it as individuals. The tails were up - there was confidence.

However, there was that feeling in the stadium… what happens if? That’s now 12 points they've lost from winning positions, and that must be frustrating for Mark Hughes.

Danny Murphy
Former England midfielder on MOTD

Sane was incredible to watch, maybe he’s had a point to prove, there have been question marks over his character and personality. What I saw is a player who is hungry, working hard both ways. He’s devastating. Running with pace and making the right decisions. He has the desire to work hard, that’s what Pep wants. Bournemouth couldn’t cope with him. He was too good for them. We have eulogised over so many City players but I had to pick him out. He’s so young there is more to come, it is incredible. He was fantastic

The Euro 2020 qualifying draw is currently taking place so head over to Pat Jennings' live text to find out who everyone's potential opponents are.

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Manchester City saw off Bournemouth to increase their lead at the top of the table to five points, as goals flew in across the Premier League on Saturday.

The champions were made to work as the Cherries levelled through Callum Wilson, before Raheem Sterling and Ilkay Gundogan wrapped up a 3-1 win.

Crystal Palace earned their first home win of the season as they saw off Burnley, while Brighton fought back to beat 10-man Huddersfield.

And there were four first-half goals in the evening game at St Mary's as Manchester United fought back from 2-0 down to earn a point at struggling Southampton.

Here's a round-up of yesterday's action.

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Super Sunday!

Image source, BBC Sport

DERBY DAY!

It's the day where families clash, neighbours don't speak and bragging rights are earned. Who will be covered in glory? And who will want to stay at home tomorrow morning?

Everything thing is at stake when Arsenal host Tottenham at 14:05 GMT.

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Then it's over to Merseyside as Liverpool hope to retain their impressive record against Everton at 16:15 GMT.

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But first up is another London clash between Chelsea and Fulham at 12:00 GMT.

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