Andrew Hughes clears one off the line as Armando Broja rounds the keeper and tries to place it in from a tight angle.

Raheem Sterling's shot is then deflected into the side-netting.

Those four that have come on for Aston Villa have scored a combined 28 goals this season.

Villa have got 20 minutes to try and get at least one that could ensure this doesn't go to a replay.

Image source, Reuters

Danny Gabbidon
Former Wales defender on BBC

That is top, top quality from Raheem Sterling. It's always difficult to get it up and over the wall from there.

Neil Lennon
Former Celtic manager on BBC Radio 5 Live

I understand why Unai Emery wants to make the changes because Middlesbrough are the better team at the minute.

Image source, Getty Images

Unai Emery makes a quadruple change.

Moussa Diaby, Ollie Watkins, Douglas Luiz and Nicolò Zaniolo are all on for Leon Bailey, John McGinn, Leander Dendoncker and Jhon Durán.

Not a bad bunch of players to be able to call upon...

Benjamin Whiteman brings down Cole Palmer on the edge of the box now. Preston are starting to tire.

There was a very brief check for offside by a team-mate in the goalkeeper's line of sight but there's no way you can rule that goal out and the VAR review is over in a matter of seconds.

Neil Lennon
Former Celtic manager on BBC Radio 5 Live

Excellent pressure from Middlesbrough, the crowd are really getting up for this, they're enjoying what they're seeing.

Dion Dublin
Former England striker on BBC One

Middlesbrough feel they have a chance now, this is their window of opportunity.

Middlesbrough have their second corner of the game but Daniel Barlaser's delivery is powerfully headed away.

The hosts, roared on by the home crowd, come forward again soon after, winning another corner, but this one is also dealt with.

Oooh, Noni Madueke almost beats Benjamin Whiteman but the Preston defender recovers after losing his balance to poke it out for a corner.

Raheem Sterling is slipped in by Enzo Fernandez after Alan Browne gives it away in midfield.

Sterling dances past a few challenges but is stopped by Benjamin Whiteman before he can get a shot off.

Alfie Gilchrist and Mykhailo Mudryk are off. On comes Noni Madueke and Thiago Silva.

Middlesbrough made a couple of changes a few minutes ago with Hayden Hackney and Josh Coburn making way for Emmanuel Latte Lath and Jonny Howson.

Mykhailo Mudryk curls it in from the left and Armando Broja should have his second of the match.

He gets in front of the keeper and flicks it onto the crossbar.

Leander Dendoncker tries his luck from distance, it is a decent hit but the goalkeeper is right behind it.

A goal does not feel far off, however.

Alex Moreno goes down inside the box, he appears to get caught by Isaiah Jones but the referee waves away penalty appeals.

There's no VAR in this game with the hosts being in the Championship but looking at the replays I think Villa might have got one if there was VAR.