Leverkusen make a change up front as Victor Boniface replaces Patrik Schick.

Diogo Jota is brought down just outside the box with his first touch. There's strong appeals for a penalty but it is just outside.

Matteo Ruggeri gets a yellow card and Jota's name is chanted around Anfield.

Immediate impact.

Good save from Villa keeper Emiliano Martinez to keep out Gabriel Gudmundsson's diving header.

Another Martinez stop from the resulting corner, this one to stop Hakon Arnar Haraldsson's flicked shot on the line.

Diogo Jota is back from injury and this is a big boost for Liverpool. Can he give them what they need tonight? He replaces Wataru Endo.

Image source, PA Media

Another massive chance for Atalanta with a three-on-two break after Liverpool lose possession near the halfway line.

Gianluca Scamacca can't get past Wataru Endo though, and it's deflected comfortably to Caoimhin Kelleher.

Leverkusen midfielder Granit Xhaka drills in a shot from 20 yards out but it's wide of the goal. Lukasz Fabianski had it covered anyway.

West Ham striker Michail Antonio runs into the box but his cut-back is behind a team-mate.

Image source, Getty Images

Brilliant save from West Ham keeper Lukasz Fabianski to claw Patrik Schick's close-range header over the bar.

The first shot for either side in the second half. There were 19 in the first half (18 to Leverkusen).

Stephen Warnock
Former England and Liverpool defender on BBC Radio 5 Live

They need to do something, Liverpool. They need to get a moment of magic from somewhere. Individually or collectively.

It looks like it might have to be individually.

This is arguably the worst performance I have seen under Jurgen Klopp. That is how bad it is tonight.

Bayer Leverkusen bring on England-born Nigeria international Nathan Tella for England-raised Netherlands international Jeremie Frimpong at right wing-back.

Joe Gomez fizzes an effort just wide of the right post from long range. Not a bad strike in the end.

Nicolo Zaniolo replaces Morgan Rogers for Villa. They made that sub while they were waiting for the VAR decision.

Just two shots on target for Liverpool, five for Atalanta. Another Reds' attack breaks down and Atalanta have the ball on their right-hand side.

Image source, PA Media

A big boost for Aston Villa as Lille have their goal disallowed for offside.

Paul: Liverpool are flat. Anfield is flat. It’s been poor from the first whistle. Need to buck up here or they’re being dumped out of the tournament on a whimper.

Andrew: Atalanta cutting the Liverpool defense open tonight, like a hot knife through butter.

Ali: Liverpool lack cutting edge to their game. It's been poor from them for a while now. Salah has been desperately poor since coming back from injury. Nunez and Diaz are always missing chances. You don't win anything like this.

Mohamed Salah is offside as he's slipped in by Dominik Szoboszlai. Atalanta are defending well at the moment and Liverpool have no answers.

West Ham are 27 minutes away from becoming the sixth team not to lose to Bayer Leverkusen all season.

Atalanta are running the show!

Teun Koopmeiners should make it 3-0 but he drags the shot wide from the left side of the box.

Again, he was unmarked. This is unbelievable at Anfield.

Image source, Getty Images

Anon: The arrogance of this Liverpool side tonight. Both players and fans haven’t turned up tonight and we deserve to be 2-0 at this point.

Conor: Pathetic from Liverpool. Absolutely Pathetic.

Mark: This is embarrassing from Liverpool.