Watch: Parsons and Considine star in Ireland winpublished at 19:26 British Summer Time 10 April 2021
Women's Six Nations: Parsons and Considine score brace as Ireland beat Wales
Ireland beat Wales in Pool B at Cardiff Arms Park
Wales lost 53-0 against France in opening game
Ireland didn't play in first round of fixtures
Women's Six Nations: Parsons and Considine score brace as Ireland beat Wales
Wall charges over to add to Ireland lead over Wales
Parsons scores Ireland's second try with solo run
Wales full-back Robyn Wilkins will win her 50th cap as Warren Abrahams' side host Ireland.
Abrahams makes four changes from the heavy France defeat, including a start for Courtney Keight in place of Jasmine Joyce.
Wales: Robyn Wilkins; Lisa Neumann, Hannah Jones, Kerin Lake, Courtney Keight; Elinor Snowsill, Jess Roberts; Cara Hope, Kelsey Jones, Cerys Hale, Natalia John, Gwen Crabb, Georgia Evans, Manon Johnes, Siwan Lillicrap (capt)
Replacements: Molly Kelly, Caryl Thomas, Donna Rose, Teleri Wyn Davies, Bethan Dainton, Megan Davies, Niamh Terry, Caitlin Lewis
Ireland Sevens back Eve Higgins will make her Six Nations debut at centre in Saturday's opener against Wales in Cardiff.
Head coach Adam Griggs has also included uncapped backs Emily Lane and Stacey Flood in his 23-player squad.
Eimear Considine returns at full-back with Beibhinn Parsons lining out on the left in the other two changes from Ireland's win over Italy in October.
Ireland: Eimear Considine, Lauren Delany, Eve Higgins, Sene Naoupu, Beibhinn Parsons, Hannah Tyrrell, Kathryn Dane; Lindsay Peat, Cliodhna Moloney, Linda Djougang, Aoife McDermott, Nichola Fryday, Dorothy Wall, Claire Molloy, Ciara Griffin.
Replacements: Neve Jones, Katie O'Dwyer, Laura Feely, Brittany Hogan, Hannah O'Connor, Emily Lane, Stacey Flood, Enya Breen.
Back-to-back Grand Slam winners England dominated their Women's Six Nations opener against Scotland, securing an eight-try victory to win 52-10.
Women's Six Nations: 'Brilliant' Breach's solo try as England thrash Scotland
France kicked off their 2021 campaign with a statement as they also ran eight tries to see off Wales 53-0 in Vannes. It took winger Caroline Boujard less than 15 minutes to score a hat-trick.
Women's Six Nations 2021: Boujard scores first half hat-trick for France against Wales
Here's how things stand after round one - England are top of Pool A while France sit top of Pool B. Scotland have a rest weekend before facing Italy in round three.
BBC iPlayer
The Women's Six Nations is being completed in a new format this year because of the coronavirus pandemic. The six teams have been separated into two groups with each playing two pool games before a final weekend of fixtures to decide placings.
All of the games will be available to watch live, and to catch-up on for 30 days, on BBC iPlayer and the BBC Sport website and app. Wales' game on Saturday, 10 April against Ireland will be available on BBC Two Wales, while England's final game two weeks later will be available on BBC Two.
Saturday, 10 April
Round two
Italy v England (14:00 BST) - BBC iPlayer and the BBC Sport website & app
Wales v Ireland (17:00 BST) - BBC Two Wales, BBC iPlayer and the BBC Sport website & app
Saturday, 17 April
Round three
Ireland v France (14:15 BST) - BBC iPlayer and the BBC Sport website & app
Scotland v Italy (17:00 BST) BBC iPlayer and the BBC Sport website & app
Finals will take place on Saturday, 24 April.