The big news from the Manchester City camp is that Pep Guardiola has insisted with James Trafford in the goal with Ederson's future at the club uncertain.
They make four changes from the 2-0 defeat by Tottenham last week, including a first start for Rodri since a 2-2 draw with Arsenal in September 2024. Matheus Nunes, Abdukodir Khusanov and Bernardo Silva also come in.
Manchester City XI: Trafford, Reijnders, Stones, Marmoush, Rodri, Silva, Ait-Nouri, Nunes, Khusanov, Bobb, Haaland.
Sutton's predictions: Brighton v Man Citypublished at 11:00 BST 31 August
11:00 BST 31 August
Which Manchester City side will we see? I said last week on Football Focus and Final Score that the goalkeepeing situation with James Trafford worries the life out of me. I don't think he should be playing ahead of Ederson, even if there is talk of Ederson leaving.
Brighton should've won their first game against Fulham - they didn't and then they lost to Everton despite having a fair few chances.
This match could be anything. I think we'll find out a lot about Manchester City and whether they can be challengers because Brighton away is a difficult fixture.
Last season I backed City on so many occasions saying they'd bounce back. I got so many of the predictions wrong after they did the exact opposite and stayed on their bad run.
There's a strong chance I'll be wrong again, wouldn't be the first time, but I'm going to revert back to last season's technique and say City will pinch this.
Brighton v Man City: Key stats and talking pointspublished at 12:07 BST 30 August
12:07 BST 30 August
Tom White BBC Sport
Brighton host Manchester City on the south coast this Sunday. BBC Sport takes a look at some of the fixture's key themes.
Brighton made 11 changes for their Carabao Cup match against Oxford United in midweek, prompting an instant change in fortune in front of goal. The Seagulls, who had managed just one goal from their opening two games of the Premier League campaign despite an xG of 3.91, put six past the Championship side, including debut goals for trio Olivier Boscagli, Stefanos Tzimas and Tom Watson.
Fabian Hurzeler's side host Manchester City hoping to avoid failing to win their opening three games of a league season for the first time since their debut Premier League campaign in 2017-18. Hurzeler will take encouragement from his side's record against City in 2024-25, winning this fixture 2-1 in November before a 2-2 draw in Manchester last March.
The German is looking to become just the second manager, after Ronald Koeman, to be undefeated against Pep Guardiola in three top-flight matches.
City's 2-0 home defeat by Tottenham last weekend was a stark reminder that Guardiola still has a team in transition. He stated afterwards that his side needed "more composure with the ball" to keep improving.
One problem he doesn't have is in the striker department. Erling Haaland is due to make his 100th Premier League appearance this weekend and has been more prolific than any other player to reach that milestone. His tally of 87 goals is one more than West Bromwich Albion managed in their first 100 Premier League games.
Manchester City's recent away league form is strong – they are unbeaten in their past five on the road, without conceding a goal. On Sunday, they can set a club record of six consecutive away clean sheets in the league.
The Whites, and other clubs including Lyon, had been pushing to bring in the two-cap Argentina international.
And the Elland Road side had looked favourites to sign the 20-year-old because of Brighton's preference for a loan within the Premier League, with world governing body Fifa limiting all clubs to six overseas temporary moves.
Buonanotte is capable of playing as a number 10 or on the right wing and spent last season with Leicester City.
Sima completes move to Lenspublished at 17:13 BST 29 August
17:13 BST 29 August
Image source, Getty Images
Brighton striker Abdallah Sima has joined Ligue 1 side Lens for an undisclosed fee.
The Senegalese striker failed to make an appearance for the Seagulls after signing from Slavia Prague in August 2021.
During his four-year stay at the club, the 24-year-old completed loan spells at Stoke City, Angers, Rangers and most recently Brest, where he scored 10 goals in 39 appearances last season.
Albion technical director David Weir said: "This move suits all parties and gives Abdallah the opportunity to get regular game time in an environment he is familiar with and has thrived in.
"We wish him all the best for the next chapter in his career."