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Labour MP Rosena Allin-Khan says that "just as the NHS is tasked with healing and prevention, so are we in this House".

The language around the deal and empty threats are doing nothing to rebuild Britain, she says, only addressing foodbank use and properly funding the NHS will do that.

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Plaid Cymru's Westminster Leader Liz Saville Roberts says the prime minister has reached "endgame".

Ms Saville-Roberts says it is "too little too late" for the prime minister to reach out to other parties, when for the last two years "the rest of us have been invisible".

Theresa May's deal has neither credibility or veracity, Ms Saville-Roberts says, noting the situation is now "desperate".

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Conservative Nigel Evans says people had a "final say" in 2016.

"I know democracy can be difficult at times, but that is no reason to deny the democracy" which voted to leave the EU, he says.

He says he looks forward to the ability to do trade deals around the world when the UK leaves.

"It is in both our interests to come to some form of trade deal," he says.

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Conservative Geoffrey Clifton-Brown says he is "a Brexiteer by DNA" and he will honour that by voting for the deal.

The deal will provide certainty for business, he says, but he wants more.

In return for this support, he expects the government to listen to his concerns and come back with better.

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Tory Craig Tracey says the agreement does not meet the requirements set by his constituents: to regain sovereignty and to establish the ability to trade freely.

Change is possible, he says, urging the PM to go back to the EU to achieve a deal "that we can get behind".

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Labour's Chris Bryant says that "this isn't a deal to be honest" and the words are so "woolly" that the words can mean whatever the reader wants them to mean.

He says the deal will leave the UK worse off and in a worse security situation.

"I'm angry that we've wasted so much money on Brexit," he says.

The UK has "utterly squandered two years on a massive distraction" on the issues facing the UK domestically.

"We have become an international laughing stock," he says.

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Tory MP Andrew Selous says 403 constituencies voted to leave and the people in those constituencies were promised their votes would be honoured.

"I don't think it would be right to say we are going to have a second vote when we haven't delivered what they voted for the first time," he adds.

Mr Selous says if there is a majority against no-deal and if May's deal is voted down, the alternatives left, such as the Norway plan are "so far away from what the British people voted for that we will have broken the promise".

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Labour MP Liz Kendall says the backstop has dominated the debate, but the fundamental question is whether the agreement is right for the country?

She says it isn't.

No free trade agreement will deliver the same benefits as membership of the EU, she says, whilst the agreement does not provide the answers for why people voted to leave in the first place.

She says she will support moves to build a consensus across the House and prevent no deal, but also backs another public vote.

Dominic Casciani
Home Affairs Correspondent

Outside Parliament, there are probably more Remain protesters than Leavers.

While the protests have stepped up this afternoon - the gatherings are not causing a public order situation for the many, many police who are here.

The traffic is moving and people are getting on with life. Here's a slice of what's been going on.

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Conservative MP Marcus Jones says he accepts concerns raised over the backstop, and hopes if the prime minister's deal is defeated tonight, a renegotiated deal with the EU considers a time frame for it.

He adds that the UK must leave the EU on 29 March, and an extension of Article 50 or a second referendum must not be considered.

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Labour's Richard Burden says he does not blame the job losses at Jaguar Land Rover on Brexit alone, but it is "part of that picture".

He says the decision has underlined to him the importance of ruling out "crashing out without a deal".

"We've got to buy ourselves some time" to decide what should happen next after the deal is defeated, he says.

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Conservative MP John Baron, whose amendment has been selected by the Speaker, explains that it "would give the UK government the unilateral right to exit the backstop at the time of its choosing".

He says there has to be elements of compromise in negotiations, but the backstop is unacceptable.

"If the amendment is not passed, I will unfortunately have to vote against the withdrawal agreement," he says.

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SNP MP Hannah Bardell says it is "a human tragedy" that opportunities are going to be denied to the next generation, once the UK leaves the EU.

She questions the protection of rights for members of the LGBT+ community "without the carrot and stick of EU institutions".

Ms Bardell says she worries that the Erasmus scheme, which benefits thousands of students, will end if the UK leaves the EU.

BBC Radio 5 live

Leader of the Liberal Democrats Vince Cable had his say ahead of tonight's meaningful vote on Theresa May's withdrawal deal, saying "it's a divorce agreement, it isn't a deal'.

Live coverage on BBC Sounds.

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Conservative Richard Bacon says that a constituent recently told him that he was "sick and tired" of being told that people didn't know what they were voting for.

He says that the reforms secured by David Cameron were voted against by the public in the EU referendum.

The question was "straightforward," he says, and reveals he will vote against the agreement.

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Labour MP Shabana Mahmood says she cannot support the withdrawal agreement as it ignores 80% of the economy and the service sector "on which so many jobs depend".

She adds that more discussions need to be had to work out a consensus, and that a no-deal Brexit must be ruled out.

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Conservative Robert Halfon says he voted remain but he felt that the EU was undemocratic.

He says it was clear that constituents had "had enough" of the EU.

He asks how he can go back to his constituency and say that £39bn has been paid to the EU, but there isn't enough money for local libraries.

He's never voted against the current prime minister, he says, but he will tonight.

Reality Check

Conservative MP John Baron warns that the backstop is "the very real problem" for many MPs.

How does the backstop work? Reality Check's Chris Morris explains