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Labour MP Stephen Morgan says the deal will mean shortages in hospitals and it "threatens (the) prosperity needed to fund the NHS".

He adds that if a no-deal Brexit was imposed there would be a 29% increase in food import costs which would "greatly affect the poorest in our community".

Mr Morgan says he cannot jeopardise his constituency of Portsmouth's future by voting to make them poorer.

Laura Kuenssberg
BBC political editor

Playing the numbers game is dangerous - one seasoned politician who's been tracking every single move guessed at 90 against the deal this afternoon.

Other wilder claims of up to 200 against are doing the rounds too.

What you won't find today is anyone in Westminster who thinks the numbers are going to flip towards the government enough.

And that's why, although the speculation is enough to drive some people round the twist, much of the whispering today isn't about the vote itself, but about what happens next.

Read more

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DUP MP Gregory Campbell says the government "is not listening and paying attention to what the people say and want".

Mr Campbell calls for the prime minister to go back to Brussels when her deal is defeated and demand "an ultimate sense of freedom beyond the EU".

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Conservative MP Damian Collins says that he will be voting against the withdrawal agreement.

He says that it will leave the UK worse off and with "less control" over the laws that govern the country.

The deal has to be rejected, and any new deal must allow the UK to "choose our future direction", he says.

BBC Radio 5 live

Conservative MP Anne-Marie Trevelyan spoke to BBC Radio 5 Live's Anna Foster on why she she feels she has to vote against Theresa May's withdrawal deal.

Listen live on BBC Sounds.

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Conservative Mark Pritchard says that his constituency "overwhelmingly voted to leave the European Union".

He says his constituents support for Brexit is not "inconsistent" with a "fond affection for Europe".

His constituents support the rule of law, freedom of speech and democracy, he says, as well as the hard work EU citizens contribute to the UK.

The Brexit vote was not a vote against Europe, but a vote for Britain, he says.

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Labour MP David Hanson says nothing in the agreement gives any comfort on the issues of sharing information on criminals in Europe, or on trade.

Mr Hanson says he cannot support the deal, which will damage the economy by at least 2.5%, but he cannot support no-deal either as it will "destroy frictionless trade".

He says a way through the "mess" can be found.

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MPs should not be voting for a deal which will make the economy weaker, Conservative Heidi Allen says.

She says MPs are "elected to consider all options", and she warns that a future "hard no-deal Brexit" government might reverse the collaboration agreed upon by the EU and UK in this deal.

"For me the decision is clear as day, this is not good enough for my country," she says.

She calls for a second vote.

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Labour's Rachel Reeves says that her committee - Business, Energy and Industrial Strategy - has heard from business leaders who say leaving the EU is "ripping the wires out of the mainframe".

The deal will make constituents poorer and have national security implications, she says.

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The SNP's Angus MacNeil says "an Englishman would burn his own bed to catch a flea" and "that's exactly what Brexit is".

He says it is "very obvious" that the prime minister has "no plan".

The Falkland Islands and Gibraltar "don't want any of this nonsense", he states.

He says the Scottish want to get out of the UK in order to remain in Europe.

It's not just the MPs against Theresa May's deal that have their own ideas on what Brexit should look like - up and down the country, voters have very different visions of the UK's departure from the EU.

With the vote just hours away, the BBC has been canvassing their views.

Have a read here if you want to know more.

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Conservative MP Stephen Crabb says the defeat of the withdrawal agreement tonight is "a near certainty".

He says voting against the deal is the easier thing to do, but shouldn't be done if MPs believe in leaving the EU in an orderly manner.

"Voting for the deal is the right thing to do," he adds.

Mr Crabb says he is voting for the deal as he took seriously the promises he made to his constituents.

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Labour's Derek Twigg says that people in his constituency voted to end free movement and they believe that leaving the EU is the best course of action.

There is not a majority in the UK for leaving the EU without a deal, he adds.

The UK will end up being "rule takers" and won't be able to shape rules which will apply to the country, he says.

Both leavers and remainers reject the deal, he states.

Adam Fleming, the BBC's Brussels reporter, explains six actions the European Union could take if the vote in Westminster is lost tonight.

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Sir Edward Leigh says he may vote against tonight's motion if the government won't back his amendment.

His "amendment B", makes clear the Northern Ireland backstop is temporary and should remain temporary and calls for assurance that, if the backstop doesn't end by the close of 2021, this will be treated as a fundamental change of circumstances and would terminate the Withdrawal Treaty on 1 January 2022.

The amendment is backed by 15 other Tory Brexiteers and has been selected by the Speaker to be voted on tonight.

Sir Edward says the fundamental concern with the withdrawal agreement is the "fear that the Northern Ireland backstop will become permanent".

He asks for the government to seek movement on the issue if the deal fails tonight, and says the withdrawal agreement does not need to be "de-picked" to do this.

BBC News

Lib Dem leader Vince Cable says he expects a heavy defeat for Theresa May's deal this evening.

He says the government would "have champagne corks popping if [the defeat] was anything under 100 (votes), it could be much worse than that."

No amendments could persuade him to back Mrs May's deal, he says.

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Labour's Frank Field says it has become "clearer and clearer" how the "political traffic was moving".

He confirms he will now vote for the deal that has been put forward.

He says that the idea the UK needs another referendum is wrong, and he refers to referendums as "poison".

"For all of its failings, I believe we now risk losing Brexit," he says, adding that this does not "excuse the government".

He says the deal fulfills the promise of being able to control borders and stop paying cash to the EU.