We're hearing reports from Iranian state TV saying that 100 missiles have been launched in the second wave of their operation "True Promise 3".

The Israel Defense Forces say its Air Force is currently attacking military targets in Tehran, in parallel with the activity of intercepting missiles launched from Iran.

Sophie Williams
Reporting from Jerusalem

We have now had a new update from the Home Front Command telling us that missiles have been launched from Iran.

The IDF says defensive systems are operating to intercept the threat.

People have been told to enter a protected space if they hear an alarm and remain there until further notice.

The Israeli military has just sent a new update:

"The IDF (Israel Defense Forces) has identified that missiles were recently launched from Iran towards the territory of the State of Israel.

"Defense systems are working to intercept the threat. You must enter the protected areas upon receiving the alert, and remain there until further notice.

"Exiting the protected area will be permitted only after receiving explicit instructions; you must continue to act according to the Home Front Command's instructions.

Iran’s Nuclear Regulatory Authority has told the International Atomic Energy Agency (IAEA) that radiation levels outside the Isfahan nuclear site in central Iran have not changed.

This follows confirmation from IAEA that "four critical buildings" at the site were damaged following repeated Israeli strikes.

Image source, Reuters

Sophie Williams
Reporting in Jerusalem

Here in Israel, the Home Front Command has now instructed residents across the country to stay close to protected spaces.

A further strike from Iran is anticipated this evening.

We can now bring you fresh reactions from Iran as our colleagues at BBC Persian have been speaking to Tehran residents about the impact of the Israeli strikes.

One woman says she has considered leaving the capital to escape the attacks.

"We’ve all wanted to go to smaller cities or villages, anywhere we can go, but each of us has loved ones who can’t leave, and we’re thinking of them," she says. "What we’re experiencing is not fair to any of us, the people of Iran."

She also says it seems like Iranians are "paralysed", which she finds very annoying.

"We are sorry that the leaders of our country don’t care about any of us and our lives, and we’re all trying to get through these days in fear, exhaustion, and a lot of stress, this is extremely hard and painful."

Another woman tells us she hasn’t been able to sleep for two nights: "I’ve gone through really tough situations."

She says the current situation reminds her of bombings and going to shelters during the Iran-Iraq war, when she was a child.

Image source, EPA

French President Emmanuel Macron has spoken with Iranian counterpart Masoud Pezeshkian.

Macron says he’s urged “the utmost restraint to avoid escalation” and calls on Iran to return to the nuclear negotiation table as soon as possible.

But Pezeshkian tells Macron that Iran will not sit at the negotiating table while Israel’s attacks continue.

This comes after a US-Iran nuclear talk, which was scheduled for Sunday, was announced as cancelled.

Image source, Getty Images

Israeli Prime Minister Benjamin Netanyahu has released another video, this time speaking in English and seemingly addressing an American audience.

He starts by wishing Donald Trump a happy birthday, then pays tribute to US servicemen and women who have "protected freedom" for 250 years.

Netanyahu says the Israeli army is also "defending freedom" in the Middle East against what he calls a "tyrannical" Iranian regime.

"Our enemy is your enemy. And by doing what we're doing, we're dealing with something that will threaten all of us sooner or later," he says.

He also says, without providing evidence, that if Israel hadn't acted, Iran would have armed its proxies – such as Hezbollah and Hamas – with nuclear weapons.

"This is what Israel is doing with the clear support of the President of the United States, Donald Trump, and the American people and many others in the world," he adds.

The White House at first tried to distance itself from Israel's attack on Iran, but later openly supported it, with Trump calling it "excellent".

Iran's defence network has started operating in Tehran, Hormozgan, Kermanshah, West Azerbaijan, Lorestan, and Khuzestan, according to the country's Tasnim news agency.

The agency also reports that a large number of drones were identified and destroyed during the day in the western provinces and Qom.

Footage shared by the agency, which the BBC has not verified, appears to show flashes and explosions in the sky.

Ghoncheh Habibiazad
BBC Persian

The governor of Iran’s north-western East Azerbaijan province says 31 people have died there, including 30 military personnel and one member of the Iranian Red Crescent.

Bahram Sarmast also says that 55 people have been injured so far.

Iran’s state television has been reporting that 60 people, including 20 children, were killed in an Israeli strike on a building in Tehran.

Iran has not yet released an official total number of casualties.

The Iranian Red Crescent says two people were killed in an attack on an ambulance in the north-western West Azerbaijan province.

Iran’s envoy to the United Nations said yesterday that Israeli strikes have killed 78 people and injured more than 320.

The BBC cannot independently confirm these claims.

We're getting an update from the Israel Defense Forces (IDF) chief spokesperson, Effie Defrin, who says, "even at this hour, the Air Force pilots continue to attack and carry out extensive strikes in various areas of Iran".

"A series of attacks that has not stopped for nearly 40 hours and includes more than 150 targets. The focus of the attacks in the past 24 hours, Tehran," he adds.

In a televised briefing, Defrin says Israel targeted an underground site in western Iran "used for storing and launching surface-to-surface missiles and cruise missiles".

"This site was attacked and the senior figures who visited it in the past were also eliminated," he says.

Defrin adds that the missiles stored there were supposed to be launched "against Israeli citizens or even against forces of other Western countries in the Middle East".

Ghoncheh Habibiazad
BBC Persian

Iran’s Ministry of Oil says in a statement that two major gas fields in Iran’s southern Bushehr province have been attacked by Israel.

Quoting eyewitnesses, Iranian outlets say the Phase 14 of South Pars Gas field was carried out by miniature UAVs. Another gas company, Fajr Jam Gas Refining Company, has also been targeted in the same province.

This is the first time we are seeing reports of Israel attacking gas fields in Iran.

BBC Verify is currently verifying footage from that area.

Steve Rosenberg
Russia editor

Image source, Getty Images

According to his foreign policy advisor Yuri Ushakov, in the fifty-minute conversation with Donald Trump, President Putin “condemned the Israeli operation against Iran".

No surprise here. Yesterday a Kremlin spokesman had "condemned the sharp escalation in tensions” in the Middle East.

But it’s clear that Moscow wants to avoid the situation in the Middle East scuppering Russia’s efforts to improve relations with Washington.

Despite Donald Trump’s suggestion yesterday that he and his team had known the Israeli attacks were coming, the Kremlin has voiced no public criticism of Washington.

Instead, Ushakov noted that in their telephone call Putin had wished Trump a happy birthday and had spoken about American Flag Day.

What’s more, according to the Kremlin, the two leaders expressed “satisfaction” with their personal relationship.

That will be music to the Kremlin’s ears.

Russia may well have concluded that good working relations with the Trump administration – plus Moscow’s offer to mediate in the Middle East – will make it increasingly unlikely that President Trump will exert pressure on Russia over the war in Ukraine.

US President Donald Trump and Russian President Vladimir Putin have discussed current tensions between Iran and Israel in a phone call this morning, the White House says.

"President Putin called this morning to very nicely wish me a Happy Birthday, but to more importantly, talk about Iran, a country he knows very well. We talked at length," the statement says, adding:

The global nuclear watchdog has just shared an update on the status of the Isfahan nuclear site in central Iran after it was repeatedly targeted by Israeli strikes yesterday.

The International Atomic Energy Agency (IAEA) writes on X that "four critical buildings" at the site were damaged "including the Uranium Conversion Facility and the Fuel Plate Fabrication Plant".

Several Iranian nuclear facilities are based in Isfahan, which Iran say are used for purely peaceful purposes, though Israel and Western powers have long suspected Tehran of secretly developing nuclear weapons.

The IAEA adds that there was no increase of off-site radiation at the Natanz plant, which was also targeted yesterday.

Image source, Getty Images

The conflict between Israel and Iran is a "powder keg [that] has already blown up", according to Robert Malley, the lead negotiator of the Iran nuclear deal during the Obama era.

Speaking to the BBC World Service’s Weekend, Malley says the current hostilities "may well last, and it may well head in a more dangerous direction".

He adds that he struggles to see how planned nuclear talks between Iran and the Trump administration could "resume any time soon".

The next round of negotiations was due to take place in Oman on Sunday - but the talks have been cancelled, according to mediator Oman.

"The Iranians… seem convinced that this was a ploy that Israel and the US put together to trick the Iranians into believing that a strike wouldn’t occur."

On the impact of Israel’s strikes, he says they have "accomplished a pretty extraordinary military and intelligence feat", but Iran still retains significant nuclear knowledge and capability.

• You can listen to the full interview with Robert Malley on BBC Sounds from tomorrow

Chris Mason and Isabella Allen
Political editor and senior political producer, travelling with the prime minister

Image source, Getty Images

The UK is sending more jets to the Middle East amid intense fighting between Israel and Iran.

The prime minister says military aircraft are being sent "for contingency support across the region".

The UK already has RAF jets in the region as part of Operation Shader.

On his way to the G7 Summit beginning in Canada tomorrow, Keir Starmer tells reporters the situation is fast moving and there are intense discussions with allies at every level.

"The constant message is de-escalate", he says.

Discussions will continue today and over the coming days.

The prime minister will not be drawn on whether the UK will be involved in defending Israel.

"I had a good and constructive discussion with Prime Minister Netanyahu yesterday, and that included discussions about the safety and security of Israel, as you would expect, between two allies."

He reiterates that the UK has "long-standing concerns" about Iran's nuclear programme and recognises Israel's right to self-defence.

"I am absolutely clear that this needs to de-escalate", he says.

Tom Bateman
US State Department correspondent

Regarding the talks that had been planned between the US and Iran on Sunday in Oman, a US senior administration official told the BBC: “While there will be no meeting Sunday, we remain committed to talks and hope the Iranians will come to the table soon.”

• What are the US-Iran talks about? Find out more here

Image source, Reuters

Tension has ramped up between Israel and Iran since Israel launched its attack on Friday.

Here’s the latest update from today:

• Israeli Prime Minister Benjamin Netanyahu has released a video message, threatening that warplanes will be seen over Tehran
• Israel says it has killed 20 Iranian military commanders since the operation began

• The Israel Defense Forces (IDF) is continuing to bomb targets in Iran - Iran's president Pezeshkian is threatening a "more severe" response if Israel doesn't stand down
• Planned nuclear talks between the US and Iran for Sunday have been cancelled, according to Oman, after Iran called them “unjustifiable” after the Israeli attacks
• Israeli families are returning to collect belongings from the remains of their homes destroyed by an Iranian strike in Rishon LeZion, near Tel Aviv, our correspondent reports

We’ll keep bringing you updates as we get them. Stay with us.