Israel's defence minister warns that "Tehran will burn" if Iran keeps firing missiles, after both sides exchanged strikes overnight
Explosions were heard in Tel Aviv, Jerusalem and Tehran after Iran launched waves of missiles in retaliation for Israeli strikes which targeted Iran's nuclear programme on Friday
Iran warns the UK, US and France it will target their bases and ships in the region if they help stop the strikes on Israel, state media reports
Downing Street hasn't responded yet, but it's understood the UK has not taken part in any military action, including efforts to defend Israel against strikes, our political correspondent reports
In Israel, officials say three people have been killed and dozens injured, while Iranian state TV reports 60 people have been killed in a strike in Tehran
Israeli PM Netanyahu has opened another open-front war, and the Iranian regime is going to see this as a battle for survival, reports Lyse Doucet
'A long night of attacks, with fears of more to come'
Iranian state media says at least two Israeli fighter jets have been shot down over Iran - this has not been independently verified.
The situation is escalating and fast-moving.
"As of this moment, [ambulance] teams have gone out to search seven locations where reports [of strikes] were received in the Dan Bloc [Tel Aviv metropolitan area]", a spokesperson for Israel's Magen David Adom ambulance service says.
Israel's national ambulance service, Magen David Adom, says five people have been injured in the Tel Aviv metropolitan area, and are being taken to hospital.
One is in a "moderate condition" and the other four have been "lightly injured" by shrapnel, it says.
We've just had a statement from the Islamic Revolutionary Guard, saying it has carried out attacks against "dozens of targets, military centres and airbases" in Israel.
According to the translated statement, Iran calls the operation "True Promise 3".
It adds that details of this operation will be given in a later announcement.
Lucy Williamson
Middle East correspondent, reporting from Tel Aviv
Several loud explosions shook the building we’re sheltering in, and we could hear other impacts nearby.
The protected space here is filling up with residents looking for protection, with another wave of missiles expected shortly.
One is praying silently, others scanning news websites where videos are showing missiles and interceptions in the skies, and direct hits on Tel Aviv.
This is the response from Iran that Israel has been expecting - all across the country, people are listening to the sound of their country at war.
As we've just reported, we have seen huge explosions in the sky over central Israel.
In the latest update from the Israeli Defense Forces (IDF), it says "the shooting continues".
"Another barrage of dozens of rockets was launched" towards Israel, the statement adds.
The IDF says that the explosions people are hearing "originate from interceptions or impacts".
We've been hearing from Iran's Supreme Leader Ali Khamenei who says Iran “will inflict heavy blows” after Israel “launched war”.
We'll bring you more details on this statement shortly. Stick with us.
We can bring you these images now from the Reuters news agency, which show bright flashes in the skies over Jerusalem in the past few minutes.
Our team in Jerusalem have also just reported hearing loud booms in the city.
Image source, Reuters
Image source, Reuters
Tom Bennett
Reporting from Jerusalem
Our team has just heard several window-rattling booms in central Israel - while here in Jerusalem we've also heard what sounds like explosions.
It's unclear at this stage if they were impacts or interceptions.
Videos posted on social media show missiles streaking through the sky.
We're now seeing huge plumes of smoke rising over Tel Aviv in Israel, around skyscrapers in the city.
The smoke is dwarfing the tall buildings around it.
It's not clear if this is from the missiles, or the interceptions. We are working to bring you more.
Ione Wells
Reporting from Jerusalem
We were just reporting live from our hotel in Jerusalem for BBC News when we spotted two drones flying over our heads, and we heard an explosion. It’s not clear if this sound was a strike or an interception of one.
Moments before, sirens and emergency alerts had gone off signalling to people to stay near shelters.
An IDF briefing was cut short after Israeli officials said they were expecting an imminent Iranian attack.
The Israeli military says Iran launched missiles towards Israel a short while ago, and its defence systems are working to stop the threat.
The public have been told to enter shelters until further notice, the statement adds.
We can now bring you more on the latest Israeli attacks on Iran, which targeted Isfahan's nuclear facility.
Air Force jets attacked the nuclear site, which is where the process of reconversion of enriched uranium takes place, according to the Israeli Defence Forces (IDF).
In a statement, it adds that this is the next stage in the process of producing nuclear weapons.
The IDF says it has "destroyed a facility for producing metallic uranium, infrastructure for converting enriched uranium, laboratories, and additional infrastructure".
Image source, EPA-EFE/ShutterstockShortly before Israel said it had carried out strikes on the Isfahan nuclear site, Iran's Supreme Leader Ali Khamenei warned that Iranian forces will "act with strength" against Israel.
Writing on X, he warns they "will not escape unscathed from this crime".
"The Iranian nation can be assured that there will be no shortcomings in this regard."
Image source, ReutersIranian air defences have been activated in parts of Tehran, Iranian media is reporting.
Video footage shared by Iranian outlets shows bright flashes in the sky, reportedly in the capital.
As we've been reporting, the Israeli military says it is continuing to strike targets in Iran
Following reports of explosions in Iran, a spokesperson for the Israeli Defence Forces says they have carried out strikes against Iran's nuclear plant in Isfahan.
This is in addition to operations in Natanz, the statement adds.
Nomia Iqbal
Reporting from the White House
Image source, Getty ImagesLots of confusion and contradictions. President Trump may say he didn’t officially approve the missile attacks but he certainly approves of them calling them “excellent.”
Some experts are even speculating it was coordinated between Trump and Netanyahu who are very close.
Trump seems to believe that due to brute force Iran will now come to the negotiation table.
As far as he is concerned, talks will still go ahead on Sunday as planned, headed by his Middle East envoy.
But it’s all a huge gamble given Iran could now use this attack as reason to have nuclear weapons for self defence.
Anthony Zurcher
North America correspondent
Image source, ReutersAs the massive size and scope of Israel's overnight attacks on Iran have come into view on Friday, Donald Trump is presented with a major new foreign policy crisis - as well as a diplomatic dilemma.
How does the American president who promised to be a peacemaker handle a dramatic military escalation in the Middle East?
In the hours after the strike, Trump appears to be struggling to find a consistent message in the face of a grave blow to his diplomatic efforts.
Last night, US diplomats reacted coolly to the first reports of the Israeli strikes. While it was clear that American forces had advance notice of what was coming, a statement from Secretary of State Marco Rubio emphasised the US was not involved in the logistics or planning of the attack.
By Friday morning, the president himself was commenting on his Truth Social account, with a sombre message directed at the Iranian leadership - more "I told you so" than a clear plan to stop the warfare.
In comments to American media outlets, though, Trump's message was more muddled. "I think it's been excellent," he said of Israel's strikes in an ABC interview. He added that the US gave Iran a chance, but they didn't take it.
Trump's strategy, at the moment, appears to be hoping that the military action jolts Iran into making new concessions – a delicate dance of distancing the US from Israel's actions while still trying to use them to gain advantage at the negotiating table.
As we've just reported, sirens were heard in Jerusalem as the Israeli military said a rocket had been launched at the country from Yemen.
In a new update, the Israeli Defence Forces says residents across Israel are instructed to stay close to protected spaces and minimise movement in open areas.
Gatherings should also be avoided, it adds, and if an alert is issued, people should go to a protected space until an official update is provided.
Jerusalem's air raid alert system was triggered a short while ago, but it has since been turned off, according to the country's official red alert system.
It comes after the Israeli military reported that they had identified the launch of a rocket from Yemen towards Israel.
They are now "operating to intercept the threat", a statement from the IDF adds.
In a post on Telegram, Israeli police say: "Jerusalem District Police are prepared to conduct scans to locate areas where weapons have fallen."
