More from Israeli Prime Minister Benjamin Netanyahu, who says Israel will "remove" the nuclear threat from Iran.

"By the end of this operation, there will be no nuclear threat to Israel, nor will there be a ballistic missile threat," he tells reporters at Soroka Hospital.

Netanyahu adds that Israel has already harmed Iran's nuclear program "very strongly".

Asked whether Iran's Supreme Leader Ayatollah Khamenei was a potential target, Netanyahu says "no one is immune".

Israeli Prime Minister Benjamin Netanyahu has spoken to reporters from the site of the damaged hospital in the south of the country.

He praises Israel's partnership with Donald Trump, which he calls "incredible", adding that he speaks to the US president "almost every day".

"I think his resolve, his determination, and his clarity, when he says Iran cannot have a nuclear weapon, and for that to take place Iran cannot enrich uranium," he says.

"He gave them the chance to do it through negotiations, they strung him along. You don't string along Donald Trump."

Asked about potential US involvement in the conflict, Netanyahu says: "It's a decision for the president to make but they're already helping a lot".

Image source, EPA

Iran’s foreign minister is set to meet his UK, French and German counterparts, along with the EU’s foreign policy chief Kaja Kallas, in Geneva on Friday, according to Iranian state news agency IRNA.

Abbas Araghchi confirmed the talks in an interview with the agency, following speculation on social media about meetings between Iranian delegations and European foreign ministers.

Araghchi will discuss Iran's nuclear programme at the meeting, AFP reports.

• We're still bringing you lines from our interview with Iran's deputy foreign minister

Responding to Trump’s repeated comments that the conflict could have been avoided if Iran accepted the nuclear deal, Khatibzadeh says they were still negotiating, until Israel “sabotaged” this with its bombardment.

The Iranian deputy foreign minister has also been asked whether Iran is developing nuclear weapons.

Earlier, the UN nuclear watchdog, the International Atomic Energy Agency (IAEA), said Iran had amassed enough uranium enriched up to 60% purity—a short technical step away from weapons grade, or 90%—to potentially make nuclear bombs.

"This is nonsense," Khatibzadeh says. "You cannot start a war based on speculation or intention." Instead, he blames Israel - saying it has nuclear warheads - for attacking Iran's nuclear sites. He calls it a "very, very bad move".

More now from Iran's deputy foreign minister, who has been speaking to the BBC's chief international correspondent Lyse Doucet.

Asked what Iran means when it says all options are on the table if Trump brings the US into the war, Khatibzadeh repeats that Iran wants diplomacy - but while the bombardment against his country continues, "no-one can go for negotiation".

"The moment that this aggression stops, of course diplomacy is the first option," he says. He adds that this is "not America's war", and if Trump does get involved, he will always be remembered as a president who entered a war he doesn't belong in.

"We think that this war is not American war," he says.

"But if they would like to get into this war, President Trump will be remembered forever for a war that it was not his war, but dragged him.

"And this will be a quagmire and this will be hell for the whole region."

As mentioned, Iran’s deputy foreign minister Saeed Khatibzadeh has just spoken to the BBC.

Asked about reports that Donald Trump approved a military plan, and what Tehran expects, he says Iran was “on the verge of reaching an agreement” in nuclear talks with the US before Israel launched its offensive to “sabotage the whole process”.

Iran cancelled talks with the US last Sunday, saying they needed to respond to Israel’s attack on Friday.

Khatibzadeh adds they are getting “backdoor messages” from the US saying Washington is not involved and won’t get involved, but Trump’s public messages are “confusing and contradictory” and suggest US involvement.

Khatibzadeh also says Iran has not contacted the Trump administration - Trump said yesterday that Iranian negotiators want to visit the White House.

Asked if there’s a way to end the war, he says Iran is defending itself after being attacked first, with hundreds of Iranian civilians killed.

Israel killed Iran’s top commanders during diplomacy, he adds.

“We are on self defence... and we are going to continue this self defence until the aggressor takes the lesson that it cannot just attack another country.”

Image source, Reuters

Iran’s Supreme Leader Ali Khamenei has told the Iranian people that “if the enemy senses that you fear them, they won’t let go of you”.

In a post on X, he says: “Continue the very behavior that you have had up to this day; continue this behavior with strength.”

On 17 June, Israeli aircraft struck the headquarters of Iran's state broadcaster in Tehran.

A live broadcast on Islamic Republic of Iran Broadcasting's TV channel was briefly interrupted after blasts were heard and the studio lights went out.

Iranian media reported that at least one staff member was killed.

We've just received some images showing the extent of the impact the strike had on the headquarters:

Image source, EPA

Image source, EPA

Image source, EPA

Iran's deputy foreign minister is now speaking to the BBC's chief international correspondent Lyse Doucet.

We'll bring you the key lines from Saeed Khatibzadeh's interview, which you can also watch live at the top of the page.

Ghoncheh Habibiazad
BBC Persian, World Service reporter

Internet in Iran has been very unstable since yesterday, leading to fewer videos and photos coming out of the country.

Iran’s Ministry of Communications confirmed earlier reports of internet restrictions.

In a statement, the Ministry accused Israel of “misusing the national communications network for military purposes”.

It’s not just about getting videos and photos. Contacting friends and family has also been very difficult today.

The BBC is not allowed to report from inside Iran, so I speak with people there using secure, encrypted messaging apps.

Accessing these apps in Iran is tough because the government has banned them.

Many people use VPNs to get around the restrictions, but even VPN access has recently become difficult.

Among the Iranian diaspora, anxiety is rising.

“I wish I had never left my family in Iran. I can’t stop thinking about their safety,” says one person.

“First day in more than a year that I can't call or text my mum in the morning,” says another.

We’re now hearing from Iranians living abroad who are desperately trying to reach friends and family in Iran.

Sepideh, who lives in Germany, tells the BBC she hasn’t heard from his family since yesterday afternoon.

“The internet is down, and I can’t make calls through WhatsApp either. There is no way to contact them directly or indirectly, and right now, I am extremely worried because I don’t know what condition my family is in,” she says.

Amin, who lives in the UK, is in a similar situation. He hasn’t heard from his family for several days and doesn’t know if they are safe.

“Even when I make direct calls, no one answers,” Armin says. “I can’t even work anymore.”

The Iran-Israel conflict has now been going on for almost a week. It started when Israel struck targets in Iran last Friday, and there’s been daily exchanges of fire since then.

According to the Washington DC-based group Human Rights Activists, around 585 people have been killed in Iran by Israel’s attacks.

The Israeli military says Iran has launched 450 ballistic missiles and hundreds of drones since Friday, killing 24 people in Israel.

The maps below show where strikes have landed in both Israel and Iran, as well as a closer look at Tehran, which has been targeted more than 100 times.

In Israel

• Soroka hospital in Beersheba, southern Israel, has been damaged by a missile strike
• The attack prompted Israel's defence minister to say Iran's leader "should no longer exist"
• Iran says it was aiming for a military site near the hospital
• Several areas in Israel were also hit overnight, with dozens of people injured

In Iran

• Israeli forces say they have attacked Iran’s nuclear sites, including the Arak heavy water reactor and the Natanz uranium enrichment plant
• Iran has filed a complaint with the International Atomic Energy Agency
• "We will get through these difficult days," says Iranian President Masoud Pezeshkian

What happens next?

• Donald Trump has approved plans to attack Iran, but hasn't made a final decision, according to the BBC's US partner CBS
• The BBC's Lyse Doucet looks at whether diplomacy is still possible

Stay with us for the latest developments.

Image source, Reuters

The director-general of Soroka Medical Centre says several wards at the hospital were "completely demolished" after it was hit by an Iranian missile this morning.

"There is extensive damage across the entire hospital, with damage to buildings, structures, windows, ceilings, across the medical centre," Shlomi Kodesh says.

He says patients had been evacuated from the northern surgical building before the strikes. "This specific building, because it's an older building, was evacuated by us in the past few days," he says, adding that the department "was empty at the time it was hit".

But other departments that still had patients in them were also affected, Kodesh says.

"We have 40 injured people from people who were in the hospital at the time. The vast majority of these staff and patients are likely wounded from broken glass, falling ceilings, and other effects."

The hospital will transfer over 200 patients to other medical centres while teams assess the damage, he adds.

Vitaly Shevchenko
BBC Monitoring's Russia editor

Image source, AFP

America’s intervention in the conflict between Israel and Iran would lead to “another terrible spiral of escalation”, Kremlin spokesman Dmitry Peskov has told Russian state news agency TASS.

The US and Russia are supporting different sides in the conflict.

While Donald Trump is demanding an “unconditional surrender” from Iran and is reportedly considering strikes against it, Moscow sees Tehran as a key ally.

Earlier this year, Vladimir Putin signed a comprehensive strategic partnership treaty with his Iranian counterpart, Masoud Pezeshkian, Article One of which says they are keen to develop defence and security cooperation.

Iran has also supplied Moscow with Shahed drones that have played a key part in Russia’s war against Ukraine.

The Russian foreign ministry has condemned Israel’s strikes as “cynical” and “unprovoked”, and just yesterday Russian deputy foreign minister Sergei Ryabkov warned the US not to provide military assistance to Israel.

“This would dramatically destabilise the whole situation,” he said.

All this sets Moscow and Washington on a collision course over the Israel-Iran crisis, and could prove to be a major hurdle in the Russia-US relationship that has been improving since Donald Trump’s re-election.

Image source, EPA

Israel's defence minister says Iran's supreme leader, Ali Khamenei, "can no longer be allowed to exist" after the Soroka hospital was hit during an Iranian missile attack, according to local media and the AFP news agency.

Speaking to journalists in Holon, near Tel Aviv, Israel Katz reportedly said: "Khamenei openly declares that he wants Israel destroyed, he personally gives the order to fire on hospitals.

"He considers the destruction of the state of Israel to be a goal...Such a man can no longer be allowed to exist."

Earlier, Iranian state media said the main target of this morning’s missile strike was a military site next to Soroka Hospital, not the hospital itself.

The US has a strong military presence in the Middle East, with plenty of bases scattered across the region, including near Iran.

Iran has warned it would hit back if the US launched an attack. The country’s Supreme Leader said yesterday that “any form of US military intervention will undoubtedly be met with irreparable harm”.

US President Donald Trump has not given a clear answer on whether the US would attack Iran, only saying, "I may do it, I may not do it" when asked about it.

Image source, Getty Images

US diplomat David Satterfield says disagreements in Washington over a possible US strike on Iran are "not over the effect" of a strike on the Fordo nuclear facility.

"It's rather whether such an action would in fact put a decisive end to the Iranian nuclear programme," he tells BBC Radio 5 Live.

"It's one thing for the US to robustly support Israel. It is another thing for the US itself, its aircraft, its weapons, to strike on Iranian soil," he adds.

Iran has repeatedly denied it is making nuclear weapons. National Intelligence Director Tulsi Gabbard has also said Iran is not building a nuclear bomb, but Trump has dismissed her comments.

Our North America correspondent Anthony Zurcher says the divide mirrors the 2003 rift over the Iraq war.

Could there still be a diplomatic breakthrough?published at 11:09 British Summer Time 19 June

11:09 BST 19 June

Lyse Doucet
Chief international correspondent

Will the next 24 hours bring the moment President Trump gives the green light to a US military plan or a breakthrough in diplomacy?

Trump is boasting he “likes to decide at the last second”.

Is this part of psychological warfare, or his belief it’s the best way to do a deal?

Iran’s foreign minister Abbas Araghchi is expected to attend talks in Geneva tomorrow with his British, German and French counterparts and the UN Security Council will convene in New York.

Other countries with close ties to Trump including Saudi Arabia, Qatar and the UAE had made it clear to him on his recent foreign tour that they don't want a war in their neighbourhood.

Trump is still hinting a negotiated agreement is possible.

Just days before Israel launched its strikes I saw Iran’s foreign minister and Oman’s top diplomat Al Busaidi, the mediator, and they were focused on talks which had been set to take place last Sunday.

There was a sense, shared by western diplomats too, a deal could be done.

But one of the main issues was whether the US would drop its demand for Iran to reduce nuclear enrichment to zero – a red line for Iran.

So Tehran and Washington are talking tough, attacks by Iran and Israel intensify, and, behind the scenes, telephone lines are burning.

Image source, NurPhoto/Getty Images

Tom Bennett
Reporting from Ramat Gan

Image source, EPA

About five hours ago, an Iranian ballistic missile struck the business district of Ramat Gan, just east of Tel Aviv, where there are several glass-panelled skyscrapers.

Just now, a large sheet of glass from a balcony dropped out of its frame and fell several floors onto a roof. A few seconds later a warped metal rod from an electrical pylon fell out of the sky.

Authorities are clearly worried about the risk of falling objects and have cordoned off most of the pavement.

About 20 people are believed to have been injured by the blast here, authorities say, and there are large rescue crews sorting through the wreckage.