The Terminally Ill Adults (End of Life) Bill lets terminally ill adults end their life if they:

• Are over 18, live in England or Wales, and have been registered with a GP for at least 12 months
• Have the mental capacity to make the choice and be deemed to have expressed a clear, settled and informed wish, free from coercion or pressure
• Are expected to die within six months
• Make two separate declarations, witnessed and signed, about their wish to die
• Satisfy two independent doctors that they are eligible - with at least seven days between each assessment

Once an application has been approved, the patient would have to wait 14 days before proceeding.

A doctor would prepare the substance being used to end the patient's life, but the person would take it themselves.

The bill defines the co-ordinating doctor as a registered medical practitioner with "training, qualifications and experience" at a level to be specified by the health secretary. It does not say which drug would be used.

It would be illegal to coerce someone into declaring they want to end their life, with a possible 14-year prison sentence.

• Read more about the bill in our digital health editor's explainer

Just after the result was read out, some MPs appeared visibly emotional as they left the Commons chamber.

Others lined up to shake hands with Labour's Kim Leadbeater, who brought the bill, and Home Office Minister Jess Phillips gave the Spen Valley MP a hug.

Majority more than halved since last votepublished at 14:35 British Summer Time 20 June

14:35 BST 20 June

Helen Catt
Political correspondent

The expectation had been that this vote would be tighter than last time, when it passed by 55.

That was largely based on a number of MPs having already publicly switched away from supporting it.

It is quite a sizeable drop, though; the majority has more than halved.

That might be something the bill’s supporters will take on board as they now prepare to take it through the House of Lords

Here's the breakdown of the vote - we'll find out shortly how each MP voted.

Chris Mason
Political editor

Take a step back, and it has been quite a few days.

This has been a week at Westminster that has seen two decisions that point to a profound, socially liberal shift.

Just a few days ago, MPs voted to change abortion legislation to stop women in England and Wales being prosecuted for ending their pregnancy.

And now, the Commons has backed a change in the law in England and Wales to allow assisted dying, or, as some opponents call it, assisted suicide.

This vote doesn’t guarantee this will happen - it will head next to the House of Lords - but it is now likely, even highly likely.

It is a colossal social change, compared by many to the Abortion Act of 1967, the abolition of capital punishment, the decriminalisation of homosexuality and the introduction of gay marriage.

MPs had a free vote in both of this week’s votes.

But it is also true that the change in the composition of the Commons at the general election – and, in particular, the arrival of hundreds of new Labour MPs – has created the climate and the mood in Parliament that has allowed both these votes to pass.

MPs in the House of Commons have voted in favour of the Terminally Ill Adults (End of Life) Bill, with 314 votes in favour and 291 against.

The bill will need to pass through the House of Lords next before it becomes law.

Brian Wheeler
Political reporter

Downing Street has been very tight lipped today about whether Keir Starmer would be casting a vote on assisted dying.

But the PM was in the chamber to watch the closing speeches and is now taking part in the vote.

He has always been scrupulous in stressing that it is a free vote, but equally clear that he is in favour of the bill - he voted for it last time and it looks like he will be doing so again.

After about three hours, the debate on the Terminally Ill Adults (End of Life) Bill has come to an end in the Commons.

MPs are now casting their votes.

We'll bring you the results as soon as we have them - we expect them within the next 15 minutes.

Conservative MP Dr Neil Hudson stands to speak to the House.

He says that the bill leaves him with many concerns.

Hudson says he's worried that vulnerable people will feel a pressure to proceed down the assisted dying path.

He also highlights his concerns about the pressure it puts on medical practitioners.

Much of the palliative care sector is being left to charity in terms of funding, Hudson says.

The Tory MP adds that he thinks it is not right that the state funds how we come in to this life but not how we leave it.

We're now hearing from Labour MP Lewis Atkinson in the Commons, who dismisses concerns about the National Health Service being unable to deliver on assisted dying services.

He argues that the NHS has shown over the decades it can safely implement change.

Atkinson says terminally-ill people can say "doctor, I want to die, turn off this machine" - saying measures under the Mental Care Act allow for this decision to be carried out.

He says the bill introduces further safeguards, adding that "this is not about the state killing people".

Image source, UK Parliament

Edinburgh West Liberal Democrat MP Christine Jardine says she "firmly believes" the bill will provide choice to those who are "suffering at the end of life".

She says the committee has gone to "extreme lengths" to put safeguards in place in the bill, ending her speech by offering her support for the bill.

Labour MP Matthew Patrick is up next.

He says that opponents of the bill have worked tirelessly to voice their concerns.

Patrick says the vote before them is on a system and the consequences of getting this wrong are severe.

If the NHS is not able to provide the highest-quality palliative care currently, would assisted dying approve that or create a one-sided choice for people, he asks.

Patrick says that he does not believe the NHS is ready to bear the weight of the system we are voting for now.

He says he's also not convinced on the issue of coercion. Patrick adds that he is worried about the 'quiet, imperceptible' kind of coercion that could emerge if the bill was to go ahead.

Image source, UK Parliament

Speaking now is Conservative MP Dr Ben Spencer, who calls the bill's safeguards "inadequate".

He agrees that some terminally-ill patients will benefit from the measures included in the bill but argues there are others "who will be harmed".

These include people in care homes, those who are feeling like, or made to feel like, a burden and people who are abused, Spencer says.

"The question before us today is do we believe this harm for the vulnerable is worth it?" he says. "I say not. I say vote down this bill."

"The status quo is failing people each and every day," says MP Paula Barker as members continue to debate the assisted dying bill in the Commons.

She says that all sides of the debate have "accepted" that "we can and must do better" for dying people and their loved ones.

The Liverpool Wavertree MP says that until the law changes, dying people are "suffering unbearably" at the end of their lives.

Barker says she's pleased the bill has brought about a "long overdue discussion" on palliative care, adding that she hopes MPs will continue to discuss how to improve it.

Image source, UK Parliament

Liberal Democrat MP Sarah Green is up next.

Green says she voted for the bill at the second reading.

She says it was because a constituent told her the current system is cruel and she faced the uncertainty of a police investigation for taking her husband to Dignitas.

Green says the inclusion of social workers in the bill has made the bill stronger.

We're now hearing from Labour MP Jess Asato, who says that if the bill advances today "there will be unintended and undesirable consequences".

The Lowestoft MP says she's concerned about coercion being used in assisted dying, adding that she believes the bill will "create harm".

She adds that even if this bill "implemented gold standard training", health professionals would not be able to identify everyone.

"There can be no room for human error or doubt."

Liberal Democrat MP Munira Wilson says she recently watched a close friend become "unable to perform the most basic of human functions", describing the experience as "utterly devastating".

Wilson says several MPs want to ensure terminally-ill people have the chance to "manage how they leave this world".

But she says the NHS is "nowhere near giving people that choice; it is absolutely creaking at the seams".

Labour MP John McDonnell is up next, he says there will never be unanimity on this issue.

He adds that including the disability advisory group was a huge breakthrough for the House and that the four year implementation schedule is important.

McDonnell tells the House that this is not a choice between palliative care and assisted dying.

Image source, UK Parliament

We're now hearing from Conservative MP Wendy Morton, who says she fears the bill would be "extended and extended" because of what she's seen happen to other countries that have legalised assisted dying.

She adds that we have to "come to terms" with debating death. She says she doesn't believe today is the "end" of the conversation.

Morton concludes that she doesn't believe the bill is in the "right place" to go forward to the House of Lords and adds that she will "vote against" it.

Image source, UK Parliament

"I believe in choice," Southend West and Leigh MP David Burton-Sampson tells the Commons.

He says he launched a local survey asking his constituents' opinions, and notes they appear to be split on the issue.

"While at this stage of my life I believe assisted dying is not for me, there are many who feel otherwise," he says, adding his concerns have been addressed and he will be supporting the bill.