The tragic tour bus crash in upstate new work has killed multiple people, but authorities have not yet confirmed how many. Here is what we know:

• Several people were killed when a tour bus lost control and crashed into a ditch on New York's I-90 freeway
• Police had initially reported that a child had died, but have since said that no children are among the fatalities
• The bus was carrying 52 people, most of them not wearing seatbelts

• After an hours-long rescue effort, survivors were taken to three hospitals.
• Staff at one local hospital said it received 24 adults patients, all expected to make a full recovery. Children were taken to a different hospital
• Passengers were mostly tourists from India, China and the Philippines driving from Niagara Falls to New York City
• Several witnesses say the bus slammed into the highway median, overcorrected and crashed into a ditch, rolling and landing upside down
• Roads in the area are just beginning to reopen, and authorities are requesting drivers with dashcam footage to aid in their investigation

We are now pausing our live coverage. You can stay up to date with any major police updates in this article.

Local journalists are sharing photos and videos of the bus being put back on its wheels.

Footage from the scene shows cranes, attached to the bus with metal chains, lifting the vehicle up and righting it.

Westbound lanes on New York's I-90 have re-opened to traffic after several hours of closure around the crash site in Pembroke.

Eastbound lanes remain closed, and drivers are advised to seek alternate routes because of delays.

New York State Patrol have asked witnesses who may have dashboard camera video of today's crash to immediately contact authorities.

According to witnesses, the bus lost control and crossed the highway median before over-correcting and crashing into the shoulder of the roadway and "overturning", police say in a new statement.

A family assistance centre has been created at a senior community centre in Buffalo, the statement adds.

Victims and their families are able to meet there for reunification.

The statement adds that medical personnel and investigators remain at the crash site.

"Emergency personnel, including State Police, local first responders, and multiple medical helicopters, are on scene providing aid and transporting victims to area hospitals."

Mercy Flight, an organisation providing helicopter and ground rescues for medical emergencies, has detailed its response to the crash.

So far, the organisation has provided eight helicopter flights, the group told BBC News in an email, transporting a total of five patients to hospital.

In addition, Mercy Flight sent 17 ambulances and "Paramedic Fly Cars" - vehicles that deliver medical personnel but do not transport patients.

Six patients were transported to hospital by ambulance, while another nine were "transported by other means with our EMTs".

"From our perspective this was an extremely well-coordinated effort on the part of Genesee County Incident Command," the organisation said, adding that other patients were also treated by agencies other than their own.

New York representative Elise Stefanik says she's praying for "the victims, the injured, and the families of those involved in the fatal bus crash".

She thanked first responders on the scene and referred locals to the New York State Thruway Authority for updates on road closures.

State Senator Patrick Gallivan also posted on X, saying, "my thoughts are with the victims & families impacted by the devastating bus accident".

We just heard from doctors at Erie County Medical Center, who received 24 patients from the crash. Child patients were taken to a different hospital.

The Erie County doctors gave us more insight into what happened after the crash.

Four medical helicopters airlifted critical victims from the crash site to receive emergency treatment, doctors say.

As the only level one trauma centre in the area, the team had to clear their emergency department for large volume of patients, who had injuries ranging from "severe" fractures to head and blunt trauma.

Some of the patients were bilingual and spoke English, but many did not, so translators and translation devices were also used.

The passengers on the tour bus were mainly visitors from India, China and the Philippines.

Speaking to the press now, Erie County Medical Center says they received a total of 24 patients, 20 of whom are still actively receiving care.

Two went to the operating room and others were moved to the intensive care unit, the medical team said.

The injuries range from head trauma to extremity fractures, and the hospital's chief of surgery expects them all to recover.

Child patients were taken to a different hospital.

Two cranes have been brought to the scene to help with the rescue, witnesses have told CBS News, the BBC's US partner.

According to reports, multiple victims remain trapped, and officials are urgently attempting to extract them from the wreckage.

CBS also reports that doctors are still rushing to the crash site.

Video from the scene shows a massive sea of emergency vehicles.

Erie County Executive Mark Poloncarz has confirmed that rescue crews have been travelling into neighbouring Genesee County, where the crash occurred, and are assisting.

In a post on X, Poloncarz confirmed that there are "multiple fatalities" due to the crash.

"There are many serious injuries, and as was just announced by New York State Police, there are multiple fatalities," he wrote.

He urged people to avoid the area, including "all local roads near the scene" as officials work to divert the major traffic jam that has formed behind the crash site.

Sakshi Venkatraman
US reporter

A local hospital says 21 of the crash victims are at their trauma centre.

All the patients received at Erie County Medical Center are adults, spokesperson Peter Cutler told me, and patients under the age of 16 are going to another children's hospital in the area.

Translators are at the hospital helping victims, the majority of whom were tourists from India, China and the Philippines, authorities said.

There's no update on the condition of the patients at this time, but we will bring you more after a hospital press conference in around half an hour.

The bus crash occurred near the New York state town of Pembroke.

The small town is about 30 miles (48km) north-east of Buffalo.

We know the bus was coming from Niagara Falls and was full of tourists.

The organisation that provides blood to hospitals in the region has issued an emergency appeal for blood donations following this deadly crash in western New York.

"Our community is facing a crisis,” said Sarah Diina, from the group ConnectLife.

"We are urging all eligible donors to act now. Blood is needed immediately to treat patients who are fighting for their lives."

The statement from the group, external urges anybody nearby to call in to make an appointment to donate as soon as possible.

"This is one of those moments when your action can directly save lives,” said Diina. “Please donate. If you can’t, help us by spreading the word."

Police say several witnesses saw the bus crash, losing control before flipping over.

Powell Stephens, a resident of Medina, New York, saw the incident.

“There was glass all over the road and people’s stuff all over the road,” he told The Buffalo News after he drove by the crash. “Windows were all shattered.”

This is a developing situation. So far we know:

• Multiple people have been killed, including one child, after a tourist bus crashed in New York state, near the town of Pembroke
• A total of 52 people, including the driver, were on board
• Authorities say it was heading towards New York City from Niagara Falls, when it lost control and ended up in a ditch
• Seven people have been taken to a trauma centre, and at least four have been airlifted to hospital
• Several children were on the bus, where many people remain trapped, according to a state trooper
• A section of the I-90 interstate remains closed while rescue efforts continue

We don't know:

• The cause of the crash
• The time of the crash
• The condition of those injured

We are working to bring you more details.

A passenger manifest form provided by the bus company confirms there were 52 people, including the driver, on board, New York police say.

Police say several witnesses saw the bus lose control before crossing to the other shoulder and overturning.

The Erie County Medical Center, a level 1 adult trauma facility, says it had received seven patients as of about 14:00 local time (19:00 BST), according to the BBC's US news partner CBS.

At least one child is among the fatalities of the bus crash, state trooper public information officer James O'Callaghan told media.

"As we're progressing through this, we're losing more people unfortunately," he says.

"Most people on the bus did not have a seatbelt on."

There were multiple children on board, and some could still be entrapped in the wreckage, he says.

Mercy Flight, a non-profit emergency air medical transport provider, says it has taken four people via helicopter to hospitals, according to the BBC's US news partner CBS.

It adds that they will be transporting at least two more.

The passengers on the bus were mostly tourists from India, China and the Philippines, state trooper public information officer James O'Callaghan told press on the scene.

He said translators are coming to help speak with the victims.