Thank you for following all the reaction to the UK's historic Brexit vote here in Oxfordshire. 

We're taking the weekend off now, but will be back from 08:00 on Monday to bring you all the news, sport, travel and weather from around Oxfordshire.

The Berks, Bucks & Oxon Wildlife Trust has called for wildlife protection to be strengthened following the vote for Brexit.

It believes EU legislation has been "crucial" in "limiting the damage to the natural environment of projects such as HS2" and protecting habitats.  

Image source, Wendy Tobitt

Chief executive Estelle Bailey (pictured second from right with Remain campaigners including Caroline Lucas) said: "Throughout the referendum campaign politicians who were advocating leaving the EU promised that wildlife protection would be strengthened and funding for wildlife-friendly farming would not be cut.

"The Berks, Bucks & Oxon Wildlife Trust will work with the government to enable those commitments to be fulfilled."

Jack Suddaby
Visual broadcast assistant

David Cameron's constituency of Witney voted to remain in the EU referendum, but the UK voted overall to leave. 

The BBC asked residents what they thought of the historic decision.

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Catherine Bearder, MEP for the South East, has told the BBC she is "very, very sad, not just for the UK but the whole of Europe" because of the referendum result.

She said the ramifications of Brexit would be "enormous" for the universities and science sector in Oxfordshire, but added: "I think we’ll muddle through, but we won’t be that voice on the world stage that we expect ourselves to be.

"Tomorrow’s another day, the sun is shining, the birds are singing, we have to move on with what we’ve got."

As for David Cameron, she said history will look on him as "foolish".

Ian Hudspeth said David Cameron made the right decision to step down as prime minister, saying a "new face" was needed to lead the party in a "new direction".

But he called the Witney MP an "honourable man". 

"I wish him, Samantha, and their family all the best for the future, and we will of course continue to work with him as the local constituency MP."

The two men have not always seen eye to eye of course - they recently argued over cuts to Oxfordshire services.

Oxfordshire County Council's leader Ian Hudspeth has said the result of the referendum should be used to "drive, not delay, the process of devolving power from Westminster and Whitehall to England's cities and counties".

"The priorities of the county council will remain the same - to support economic growth, to protect the most vulnerable, and to drive efficiency in public services," he continued. 

"To support these priorities, our work on stripping out another level of bureaucratic decision making by developing proposals for a new council for the whole of Oxfordshire will continue."

Oxford-based writer Philip Pullman, author of the acclaimed His Dark Materials trilogy, has weighed in - vividly - on the referendum result.

Victoria Prentis, MP for Banbury and one of the Conservatives in the Remain camp, has called the prime minister’s decision to stand down as "extremely sad, particularly for us in Oxfordshire". 

She added: "[David Cameron] has been a fantastic constituency neighbour, friend to Banbury and a tireless supporter of everything in Oxfordshire including the Horton General Hospital. 

"He will go down in history as a great reforming prime minister. His statement this morning was dignified, and reminded us of the vision he had for Britain. 

"We must all now work together to make it a reality."

David Williams, leader of the Green Group, Oxfordshire County Council, says Brexit poses a "serious challenge to economic, social and environmental progress of the UK".

He says the council has the "unenviable task of trying to make something positive out of the transition period after which the UK leaves the EU".

Oxford Mail reporter Georgina Campbell has tweeted this picture of St Giles' Cafe in Oxford, which appears to have closed in protest at the referendum result.

They do reopen tomorrow though.

Ginette Camps-Walsh, from the Oxfordshire branch of the European Movement which has been campaigning to remain in the EU, said she was "appalled" by the national decision to leave.

"This is the result I absolutely dreaded," she said.

Of the voters who opted for Brexit, she said: "I think they've actually voted about migration and they haven't realised the economic consequences.

"You can see what's happened to the pound and the stock markets this morning - all our worst fears are coming to fruition."

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Greg Wiggall says: "Oxford voted to stay in cos that's where the people with plenty of dosh live."  

But Deborah Axtell says: "Today is a dark day for the country."

Christine Watkins says: "Disastrous."  

Oxford had one of the lowest Leave votes in the country, as this simple but fascinating (and very green) bar chart shows.

Mark Charter, head of estate agents Carter Jonas' Oxford office had a positive message in the wake of the leave vote.

Image source, Carter Jonas

"Looking forward, we firmly believe that fundamentals will continue to drive the UK property market. 

"The UK has one of the largest and most sophisticated property markets in the world and because of this it should remain a magnet for global occupiers and investors.” 

Professor Alistair Fitt, vice-chancellor at Oxford Brookes University, says the government's priority for universities should be ensuring staff and students from EU countries can continue to work and study at British universities.

Bethan Phillips
Political reporter, BBC Radio Oxford

David Cameron has a lot of loyal supporters in Witney. 

He isn't a distant figure in Westminster - he is someone that campaigns here, gets involved in local issues, and during election time, goes door-to-door to gain support. 

I was with one local Conservative activist as the news broke - he was visibly shaking with shock. 

The big question now for Witney - will David Cameron stay on as MP, after he steps down as prime minister?

Image source, Getty Images

The UK has voted to leave the EU - a process that has come to be known as Brexit. Here is what is likely to happen next.    

Nicola Blackwood said she was "very sad" to watch David Cameron announce his upcoming resignation.

She said: "As fellow Oxfordshire MPs we haven’t always seen eye to eye but he has always had my support as leader of our party because I know him to be a man who loves this country deeply and who is willing to fight for what he believes even if it is politically inconvenient. 

"He is a true statesman and we will miss him."