Rehman Chishti, the MP for Gillingham and Rainham, has announced his resignation as vice-chairman of the Conservative Party and also trade envoy to Pakistan.

Mr Chishti cites both the draft withdrawal agreement and the "lack of leadership" shown by the government in the Asia Bibi case.

MSPs at Holyrood will vote on the Brexit deal before the UK Parliament does, Scottish Constitutional Relations Secretary Mike Russell has said.

He said that while the withdrawal agreement was "essentially dead", the Scottish Parliament would have a symbolic vote on it.

In a statement to Holyrood, Mr Russell said: "The Scottish Government will bring the deal, if agreed at the Brussels Summit on November 25, to this chamber for a vote, before a vote takes place in the House of Commons."

But, he added: "Brexit isn't a better future - it is a backward step into an imagined past.

"We must acknowledge that this deal is unacceptable to Scotland and her citizens. It therefore cannot be supported by this Government.

"This deal is the inevitable result of a series of self-imposed draconian red lines. It is now essentially dead.

"We must find a way to work together and ensure that our country is not failed by a disastrous Brexit, but enabled to flourish by choosing a different way forward."

Frances O'Grady, general secretary of the Trades Union Congress (TUC), says the proposed deal should be put to the public, either via a new referendum or a general election.

"I would always say, as a negotiator, that a deal has to go back to our members.

"I think people should have the final say, whether that's through a general election or a popular vote, people's vote.

"One way or another people deserve the final say because it's their livelihoods and their rights at work that are on the line."

BBC News Channel

Labour MP David Lammy says a second referendum now looks like the best option.

Speaking to the BBC News Channel, he said: "I think we're heading towards a constitutional crisis.

"We've got 10 days until the EU ratify this deal on the 25th.

"There'll be a leadership challenge, I suspect, against Theresa May in that period, so whether she remains prime minister we're not clear.

"What's absolutely clear is that she can't get this deal through Parliament, so my view is politics is stuck, it's going to remain stuck here in Westminster for some time.

"The only way out of this is to somehow go back to the people."

The deputy political editor at Sky News and a BBC political reporter look ahead to a possible vote of confidence in Theresa May, should the 1922 committee receive the requisite 48 letters from MPs.

BBC News Channel

The UK's biggest banks have been summoned for a call with City regulators over market turbulence, according to a report from Reuters.

Bank of England governor Mark Carney personally ordered the call to be held between regulators and lenders, said the report.

A spokesman for the Financial Conduct Authority said: "As you would expect, in this type of situation, we have regular contact with firms and will continue to engage with them."

The pound fell sharply against most major currencies today, falling 1.5% to 1.28 US dollars and was also 1.5% down at 1.13 euros.

Image source, EPA

Poland’s Prime Minister Mateusz Morawiecki said protecting the rights of Polish citizens in the UK was the most important priority for his government.

Speaking for the first time about the Brexit withdrawal agreement, he said: “I am pleased that we will meet on 25 November and confirm the package of agreements between Great Britain and the EU.

"For us, the most important thing is to preserve the rights of Poles living in the UK.

“The agreement is very important for our citizens. For our entrepreneurs it is key and the stability of relations with Great Britain depend on it.”

As speculation continues over Conservative MPs submitting letters of no confidence in the PM to the 1922 Committee, who do the bookmakers think might succeed Theresa May if a vacancy arises?

Dominic Raab - 5/1

Sajid Javid - 11/2

Boris Johnson - 6/1

Michael Gove - 17/2

Jeremy Hunt - 17/2

Jacob Rees-Mogg - 17/2

David Davis - 17/2

*Odds worked out taking the average from six bookmakers.

BBC News Channel

Image source, EPA

The Scottish Secretary, David Mundell, said he had concerns about Theresa May's deal but he would not be stepping down from the Cabinet.

He criticised those who had, telling BBC News: "I'm disappointed that colleagues have resigned.

"We had a full and frank discussion inside the cabinet yesterday.

"I thought we abided by collective responsibility.

"People maybe had reservations about the deal but they signed up for it on that collective basis and I would have hoped that they would have stood with the prime minister."

Steve Baker, a fellow European Research Group member who stood next to Mr Rees-Mogg as he gave his statement, tweets a picture of his letter of no confidence in Theresa May, sent last month to the chairman of the 1922 Committee.

Image source, Houses of Parliament

The Liberal Democrats' Brexit spokesman Tom Brake says ministerial resignations and "Brexit chaos" are hitting UK businesses hard, as reports circulate that a number of firms are seeing their share prices fall.

"But the short-term damage caused by a rudderless government will be nothing compared to the permanent harm the PM’s bad deal or catastrophic No Deal would inflict on UK Plc," he adds. "That is why we need a People’s Vote to get us out of this mess and secure an exit from Brexit.”

BBC News Channel

Foreign Office Minister Sir Alan Duncan said Jacob Rees-Mogg's press conference was "absurd" and "deeply destructive... without any kind of constructive purpose".

The Tory MP told BBC News: "If he thinks that anyone can do better, he has yet to outline how.

"If he thinks there could be a better deal, he is yet to outline how.

"And if, in fact, what he wants is no deal, then he should have the honesty to say so, so we know then quite what we are dealing with with him and those he is dealing with in the party."

There's a suggestion from the Sky News presenter that if Graham Brady gets the 48 letters needed to trigger a confidence vote in Mrs May today, then that vote will take place in five days.

Sophie Pierce
BBC Radio Devon

The Conservative MP for Newton Abbot, Anne Marie Morris,said it was "time for Mrs May to consider her position".

Her views come as the prime minister faces a grilling from MPs in the Commons over her draft Brexit agreement deal.

Four members of Theresa May's cabinet have resigned but Mrs May insists the agreement would deliver the Brexit people voted for and allow the UK to take back control of its "money, laws and borders".

So what do people in Anne Marie Morris' constituency of Newton Abbot think?

Do they agree with their MP and think Theresa May should step down?

BBC Radio 5 live