Sunday 7th September
Week 1
- San Francisco 49ers vs Seattle Seahawks, ScheduledSan Francisco 49ersRecord: 0 wins, 0 lossesSeattle SeahawksRecord: 0 wins, 0 lossesVenue: Lumen Field - Seattle, WA
Sunday 14th September
Week 2
- San Francisco 49ers vs New Orleans Saints, ScheduledSan Francisco 49ersRecord: 0 wins, 0 lossesNew Orleans SaintsRecord: 0 wins, 0 lossesVenue: Caesars Superdome
Sunday 21st September
Week 3
- Arizona Cardinals vs San Francisco 49ers, ScheduledArizona CardinalsRecord: 0 wins, 0 lossesSan Francisco 49ersRecord: 0 wins, 0 lossesVenue: Levi's Stadium - Santa Clara, CA
Sunday 28th September
Week 4
- Jacksonville Jaguars vs San Francisco 49ers, ScheduledJacksonville JaguarsRecord: 0 wins, 0 lossesSan Francisco 49ersRecord: 0 wins, 0 lossesVenue: Levi's Stadium - Santa Clara, CA
All times are UK and subject to change. BBC is not responsible for any changes.