Thursday 27th February
3rd Round
- Internacional 1 , Deportes Tolima 0 at Full time , Internacional win 1 - 0 on aggregateInternacionalDeportes TolimaAggregate score Internacional 1 , Deportes Tolima 0Full time
- Club Guaraní 2 , Palestino 1 at Full time , Club Guaraní win 3 - 1 on aggregateClub GuaraníPalestinoAggregate score Club Guaraní 3 , Palestino 1Full time
Wednesday 26th February
3rd Round
- Atlético Tucumán 1 , Independiente Medellín 0 at Full time , Atlético Tucumán 1 , Independiente Medellín 1 on aggregate , Independiente Medellín win 4 - 2 on penalties , Independiente Medellín win 1 - 1 on aggregateAtlético TucumánIndependiente MedellínAggregate score Atlético Tucumán 1 , Independiente Medellín 1Full timeIndependiente Medellín win 4 - 2 on penalties
- Cerro Porteño 0 , Barcelona 4 at Full time , Barcelona win 5 - 0 on aggregateCerro PorteñoBarcelonaAggregate score Cerro Porteño 0 , Barcelona 5Full time
Thursday 20th February
3rd Round
- Barcelona 1 , Cerro Porteño 0 at Full time , Barcelona win 5 - 0 on aggregateBarcelonaCerro PorteñoFull time
- Deportes Tolima 0 , Internacional 0 at Full time , Internacional win 1 - 0 on aggregateDeportes TolimaInternacionalFull time
- Palestino 0 , Club Guaraní 1 at Full time , Club Guaraní win 3 - 1 on aggregatePalestinoClub GuaraníFull time
Wednesday 19th February
3rd Round
- Independiente Medellín 1 , Atlético Tucumán 0 at Full time , Independiente Medellín win 1 - 1 on aggregateIndependiente MedellínAtlético TucumánFull time
Friday 14th February
2nd Round
- Sporting Cristal 2 , Barcelona 1 at Full time , Barcelona win 5 - 2 on aggregateSporting CristalBarcelonaAggregate score Sporting Cristal 2 , Barcelona 5Full time
Thursday 13th February
2nd Round
- Atlético Tucumán 2 , The Strongest 0 at Full time , Atlético Tucumán 2 , The Strongest 2 on aggregate , Atlético Tucumán win 6 - 5 on penalties , Atlético Tucumán win 2 - 2 on aggregateAtlético TucumánThe StrongestAggregate score Atlético Tucumán 2 , The Strongest 2Full timeAtlético Tucumán win 6 - 5 on penalties
- Corinthians 2 , Club Guaraní 1 at Full time , Club Guaraní win 2 - 2 on aggregateCorinthiansClub GuaraníAggregate score Corinthians 2 , Club Guaraní 2Full time
Wednesday 12th February
2nd Round
- Deportes Tolima 1 , Macará 0 at Full time , Deportes Tolima win 2 - 0 on aggregateDeportes TolimaMacaráAggregate score Deportes Tolima 2 , Macará 0Full time
- Cerro Porteño 1 , Universitario 0 at Full time , Cerro Porteño win 2 - 1 on aggregateCerro PorteñoUniversitarioAggregate score Cerro Porteño 2 , Universitario 1Full time
- Palestino 5 , Cerro Largo 1 at Full time , Palestino win 6 - 2 on aggregatePalestinoCerro LargoAggregate score Palestino 6 , Cerro Largo 2Full time
Tuesday 11th February
2nd Round
- Deportivo Táchira 2 , Independiente Medellín 0 at Full time , Independiente Medellín win 4 - 2 on aggregateDeportivo TáchiraIndependiente MedellínAggregate score Deportivo Táchira 2 , Independiente Medellín 4Full time
- Internacional 2 , Universidad de Chile 0 at Full time , Internacional win 2 - 0 on aggregateInternacionalUniversidad de ChileAggregate score Internacional 2 , Universidad de Chile 0Full time
Friday 7th February
2nd Round
- Barcelona 4 , Sporting Cristal 0 at Full time , Barcelona win 5 - 2 on aggregateBarcelonaSporting CristalFull time
Thursday 6th February
2nd Round
- Club Guaraní 1 , Corinthians 0 at Full time , Club Guaraní win 2 - 2 on aggregateClub GuaraníCorinthiansFull time
- The Strongest 2 , Atlético Tucumán 0 at Full time , Atlético Tucumán win 2 - 2 on aggregateThe StrongestAtlético TucumánFull time
Wednesday 5th February
2nd Round
- Independiente Medellín 4 , Deportivo Táchira 0 at Full time , Independiente Medellín win 4 - 2 on aggregateIndependiente MedellínDeportivo TáchiraFull time
- Macará 0 , Deportes Tolima 1 at Full time , Deportes Tolima win 2 - 0 on aggregateMacaráDeportes TolimaFull time
- Cerro Largo 1 , Palestino 1 at Full time , Palestino win 6 - 2 on aggregateCerro LargoPalestinoFull time
- Universitario 1 , Cerro Porteño 1 at Full time , Cerro Porteño win 2 - 1 on aggregateUniversitarioCerro PorteñoFull time
Tuesday 4th February
2nd Round
- Universidad de Chile 0 , Internacional 0 at Full time , Internacional win 2 - 0 on aggregateUniversidad de ChileInternacionalFull time
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