Tuesday 28th February
2nd Round
- Cerro Porteño 1 , Curicó Unido 0 at Full time , Cerro Porteño win 2 - 0 on aggregateCerro PorteñoCuricó UnidoAggregate score Cerro Porteño 2 , Curicó Unido 0Full time
Friday 24th February
2nd Round
- Deportivo Maldonado 0 , Fortaleza 0 at Full time , Fortaleza win 4 - 0 on aggregateDeportivo MaldonadoFortalezaFull time
- Universidad Católica 0 , Millonarios 0 at Full time , Millonarios win 2 - 1 on aggregateUniversidad CatólicaMillonariosFull time
Thursday 23rd February
2nd Round
- Boston River 0 , Huracán 0 at Full time , Huracán win 1 - 0 on aggregateBoston RiverHuracánFull time
- Carabobo 0 , Atlético Mineiro 0 at Full time , Atlético Mineiro win 3 - 1 on aggregateCaraboboAtlético MineiroFull time
- Magallanes 3 , Always Ready 0 at Full time , Magallanes win 6 - 1 on aggregateMagallanesAlways ReadyFull time
Wednesday 22nd February
2nd Round
- Curicó Unido 0 , Cerro Porteño 1 at Full time , Cerro Porteño win 2 - 0 on aggregateCuricó UnidoCerro PorteñoFull time
- El Nacional 2 , Independiente Medellín 2 at Full time , Independiente Medellín win 4 - 3 on aggregateEl NacionalIndependiente MedellínFull time
Tuesday 21st February
2nd Round
- Nacional Asunción 2 , Sporting Cristal 0 at Full time , Sporting Cristal win 5 - 3 on aggregateNacional AsunciónSporting CristalFull time
Friday 17th February
1st Round
- Zamora 0 , Boston River 1 at Full time , Boston River win 4 - 1 on aggregateZamoraBoston RiverAggregate score Zamora 1 , Boston River 4Full time
Thursday 16th February
1st Round
- El Nacional 3 , Nacional Potosí 1 at Full time , El Nacional win 9 - 2 on aggregateEl NacionalNacional PotosíAggregate score El Nacional 9 , Nacional Potosí 2Full time
Wednesday 15th February
1st Round
- Nacional Asunción 3 , Sport Huancayo 1 at Full time , Nacional Asunción win 4 - 3 on aggregateNacional AsunciónSport HuancayoAggregate score Nacional Asunción 4 , Sport Huancayo 3Full time
Friday 10th February
1st Round
- Boston River 3 , Zamora 1 at Full time , Boston River win 4 - 1 on aggregateBoston RiverZamoraFull time
Thursday 9th February
1st Round
- Nacional Potosí 1 , El Nacional 6 at Full time , El Nacional win 9 - 2 on aggregateNacional PotosíEl NacionalFull time
Wednesday 8th February
1st Round
- Sport Huancayo 2 , Nacional Asunción 1 at Full time , Nacional Asunción win 4 - 3 on aggregateSport HuancayoNacional AsunciónFull time
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