Caicedo and Lavia miss outpublished at 01:35 British Summer Time
Palmeiras v Chelsea (02:00 BST)
Nizaar Kinsella
BBC Sport football news reporter
Chelsea are without key defensive midfield duo Moises Caicedo and Romeo Lavia.
Manager Enzo Maresca has decided against drafting in young deputies Andrey Santos and Dario Essugo.
He has instead opted to move captain Reece James from defence into midfield and lining him up alongside Enzo Fernandez in a deeper role while bringing in Christopher Nkunku.
Meanwhile, Palmeiras are without three key defenders Joaquin Piquerez, Gustavo Gomez and Murilo.