Liverpool failed to win each of their first four UEFA Champions League games against Atlético Madrid between 2008 and 2020 (D2 L2), but won home and away against them in the last campaign when they faced (2021-22 in the group stage).

Since eliminating Liverpool from the 2019-20 UEFA Champions League with wins home and away in the last 16 (4-2 on aggregate), Atlético Madrid have only won one of their last eight matches against English sides in the competition (D2 L5), winning 1-0 at Manchester United in March 2022.

Liverpool boss Arne Slot has faced Diego Simeone’s Atlético Madrid on two previous occasions in Europe, losing home (1-3) and away (2-3) against them in the 2023-24 UEFA Champions League group stage. Despite conceding six goals and scoring just three, Slot’s Feyenoord had a higher xG (3.6 – 2.1) and more shots (29 – 16) across the two meetings combined.

Atlético Madrid have only lost one of their last 10 opening games of a UEFA Champions League campaign (W5 D4), with that lone defeat coming away to Bayern Munich in October 2020 (4-0 to the German side).

Atlético Madrid have kept a clean sheet in 42% of their UEFA Champions League matches under Diego Simeone (48/115); the highest percentage for any Spanish team to play 50+ games under a specific manager, ahead of Pep Guardiola’s Barcelona (40% - 20/50).

Liverpool finished top of the league phase in the 2024-25 edition, winning the most games and most points of any side (P8 W7 D0 L1 – 21 points). They won all four of their league phase matches at Anfield by an aggregate score of 10-1, including a win over then reigning champions Real Madrid (2-0).

Mohamed Salah has scored more goals (44) and made more assists (17) than any other Liverpool player in the UEFA Champions League. If he features here, he will also move into outright second for most appearances for the Reds in the competition, overtaking Steven Gerrard (73), and trailing only Jamie Carragher (80).

Antoine Griezmann has either scored or assisted 26% of Atlético Madrid’s goals in the UEFA Champions League (51/197); the highest percentage by any player for a team who have scored 100+ goals in the competition’s history, ahead of Lionel Messi with Barcelona (25% - 155/612).

Of centre back duos or trios with 5+ starts in the UEFA Champions League last season, Liverpool duo Virgil Van Dijk and Ibrahima Konaté had the highest clean sheet percentage of any partnership (71% - 5/7).

Atlético Madrid’s Koke is one of only four players in UEFA Champions League history to make 100+ appearances under one manager (102 for Diego Simeone), along with Ryan Giggs (134), Paul Scholes (124) and Gary Neville (109), all for Manchester United under Alex Ferguson.