All four of the previous meetings between Manchester City and Napoli in Europe have been in the group stage of the UEFA Champions League. The Citizens went winless in 2011-12 (D1 L1), before winning home and away against them in 2017-18.

Napoli have never won away to an English side in any European competition (P12 W0 D3 L9), losing at least once against six of the seven different teams they have faced (Arsenal, Burnley, Chelsea, Leeds United, Liverpool and Manchester City), with Leicester being the only exception (2-2 in UEFA Europa League in 2021-22).

Manchester City boss Pep Guardiola has faced Napoli counterpart Antonio Conte on seven occasions across all competitions, while he has lost (4) more than he has won (3). Of managers with at least two wins over Guardiola, Conte is one of only three individuals who has won more often than he has lost, along with Jürgen Klopp (11 wins, 10 defeats) and Luis Enrique (three wins, two defeats).

This will be the 17th UEFA Champions League campaign for Manchester City’s Pep Guardiola as a manager, taking him level with José Mourinho. Only three managers have been involved in more than 17 editions of the competition (since the 1992-93 rebrand): Carlo Ancelotti (22), Arsène Wenger (20) and Alex Ferguson (18).

Napoli will be the fifth different team Antonio Conte has managed in the UEFA Champions Legue (also Juventus, Chelsea, Internazionale and Tottenham), with Carlo Ancelotti (8) and Claudia Ranieri (6) the only Italians to take charge of as many clubs in the competition (since 1992/93).

Manchester City lost five of their final seven games in the 2024-25 UEFA Champions League campaign (W1 D1), as many defeats as they had suffered in their previous 61 games in the competition combined (W43 D13 L5).

Napoli and former Manchester City midfielder Kevin De Bruyne could face the Citizens for the first time since leaving the club; in the UEFA Champions League he recorded 25 assists for City, 10 more than any other player for the club in the competition.

Manchester City’s Erling Haaland is one goal away from reaching 50 in the UEFA Champions League (48 appearances), and looks all but assured to set a new record for fewest appearances to 50 UCL goals. The current best is 62 games, achieved by Ruud van Nistelrooij in 2007.

In the league phase of the UEFA Champions League last season, only two players - Vinícius Júnior (8.3) and Bradley Barcola (7.5) – averaged more carries ending in the penalty area per 90 than Napoli’s Noa Lang (7 – min. 300 minutes played).

Across all the major European competitions in 2024-25 (UEFA Champions, Europa & Conference League), Manchester City’s Rayan Cherki ranked first for chances created (46) and expected assists (5.85), while he was joint-first for total assists (8), along with Raphinha and Svit Seslar.