Joao Felix, centre, has started in Europe for Chelsea but not in the Premier League
Enzo Maresca insists Chelsea are "one team, one squad" despite effectively naming two different sides for games in Europe and the Premier League.
Last month, Blues boss Maresca made 11 changes for the Uefa Conference League game with Panathinaikos, a fixture Chelsea won 4-1 to go top of the standings after two games.
They then made 10 changes for the visit of Newcastle three days later and won that game 2-1.
Chelsea host Armenians FC Noah on Thursday and Maresca is once again expected to make wholesale changes.
"We make changes because we have 24, 25 players, all fit, all good enough to play different competitions," Maresca said.
"The season is so long, we have so many games," he added. "And for sure, all of them, they are going to play Conference League and Premier League games or FA Cup, the next one.
"I can understand that from outside, you can see two teams, but we have just one team, one squad, 24, 25 players, all fit, fortunately.
"And we're going to try to use all of them."
Chelsea top scorer Cole Palmer has not been registered for the Conference League but is currently an injury concern anyway after picking up a knock against Manchester United on Sunday.
However, forward Jadon Sancho is ruled out of the game because of illness.
