Adam and Simon Yates now crests the Col de Marie-Blanque along with David Gaudu.

Tadej Pogacar is 40 seconds behind Jonas Vingegaard. The reigning champion looks in great form.

Tadej Pogacar has nobody to help him and is being distanced by Jonas Vingegaard.

Meanwhile, Jai Hindley is about 60 seconds ahead of the second group on the road led by Giulio Ciccone.

Jonas Vingegaard attacks.

Tadej Pogacar has not gone with him.

Adam Yates and his brother Simon both crack.

So does Ineos Grenadiers Carlos RodrIguez.

Sepp Kuss leads Jonas Vingegaard and Tadej Pogacar up the Col de Marie-Blanque. The peloton has been blown apart.

Jai Hindley is on the attack.

Back in the main peloton the UAE Team Emirates and Jumbo-Visma trains are somewhat depleted.

Jonas Vingegaard has Sepp Kuss for company with Adam Yates sat alongside Tadej Pogacar.

Egan Bernal slips out of the back.

Jai Hindley's team-mate Emanuel Buchmann is in the next pairing on the road with Giulio Ciccone. They are about 15 seconds down on the leading duo.

Jai Hindley and Felix Gall attack with around four kilometres of climbing left. That has blown the leading group apart.

Here comes the Col de Marie-Blanque. This should be a cracking finish.

Omar Fraille now putting in an exceptional turn on the chasing group to bring the three leaders back into view.

The Spanish climber is working for his Ineos Grenadiers teammate Daniel Martinez here but it's also good news for Jai Hindley, who has not really had to do the hard yards yet.

Marc Soler, who is back in the yellow jersey group looks like he is coming to the end of a huge turn having reduced the arrears of the yellow jersey group to under three minutes.

Krists Neilands is reeled in by Julian Alaphilippe and Wout van Aert. They have an 18-second lead over the chasing group which contains Jai Hindley, who won last year’s Giro d'Italia.

Meanwhile, back down the road Neilson Powless is distanced by the main peloton.

The American has not enjoyed the best of days after missing the breakaway and almost certainly now losing the polka-dot jersey.

Julian Alaphilippe is out of his saddle. Wout van Aert ominously looks like this category three climb is barely troubling him.

Wout van Aert and Julian Alaphilippe have Krists Neilands in their sights. This is could be some finale.

Scratch that. Jullian Alaphilippe and Wout van Aert get away after all. They looked like they were being reeled in but have pushed on and opened up a 20-second gap of their own.

Jullian Alaphilippe and Wout van Aert's attempt to bridge the gap from the Jai Hindley group to leader Krists Neilands comes to nothing.

The Latvian has about 20 seconds, which of course can disappear in no time at all.

Not long until Krists Neilands hits the slopes of the Category 3 Col d’Ichere, which is 4.2km in length and has an average gradient of 7%.

The Latvian may just have thought he needed a little cushion heading into this one as Julian Alaphilippe tries to nip off in pursuit.

Krists Neilands has 25-second advantage over his chasers.