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Isco scored twice as a scintillating Spain beat Italy at the Bernabeu to take a huge step towards qualifying for the World Cup from Group G.

The hosts started without a striker, but did not need one with the Real Madrid playmaker curling home a free-kick and then smashing in a second.

Alvaro Morata came on to add a third from Sergio Ramos' cross.

Italy, who trail Spain by three points with a much worse goal difference, are likely to be in the play-offs.

Thanks for joining us today, we will leave you with the story of the game...

It's all over. The Azzurri suffer a first qualifying defeat in over a decade. Spain are surely going to qualify for the World Cup now.

The Bernabeu is bouncing. Party time for Spain, who look back to their best.

Two minutes added on.

A very popular substitute both ways. Two-goal Isco comes off - at his club's home ground, and David Villa comes on for his 98th cap - his first since 2013-14 when he left for New York City.

Spain think they've got a fourth goal but Alvaro Morata was well offside from David Silva's pass.

David de Gea is able to hold onto a Lorenzo Insigne shot from distance as Italy have a rare effort on target.

Spain are just seeing this one out now. Five minutes to go.

Sergio Ramos, now out on the left for some reason, volleys a shot wide after it lands to him in the box. Both he and Gerard Pique were up in the Italy box. Mavericks.

Italy make a change now as Manolo Gabbiadini replaces Ciro Immobile.

David Villa gets a fantastic reception as he warms up for Spain. Not sure if he's coming on though.

Spain make a change, with the game already won. Marco Asensio - who was actually pretty quiet - is replaced by Saul Niguez.

This game has made up for that Georgia v Republic of Ireland dross I had to watch earlier. If more qualifiers were like this, people would object to international breaks less.

Ciro Immobile runs back from an offside position - ie miles offside - the ball lands to him and he thinks 'better kick the ball into the empty net just in case it counts'. It didn't.

Federico Bernardeschi crosses but Spain clear. The hosts break and Alvaro Morata is only denied a run in goal by a good Andrea Barzagli tackle - his former Juventus team-mate.

Sho Rahman: Remember a couple of years ago when Isco could barely get on the Madrid bench. The turnaround is sensational.

Dave Wood: Wonder if PSG will meet Iscos €700m buyout clause in January?

Spain scored twice with no proper striker. Well they have one now. Chelsea's Alvaro Morata replaces Andres Iniesta. Iniesta gets a fantastic reception as he comes off. In contract to Barcelona team-mate Gerard Pique every time he gets the ball. I guess scoring a winner in a World Cup final will do that.

On comes 40m euros winger Federico Bernardeschi, who has yet to make his Serie A debut for Juventus following his summer move from Fiorentina. He replaces Andrea Belotti, who only had nine touches of the ball.

It's a double change, as Eder replaces Antonio Candreva.

Brilliant from Spain, who almost put this game to bed. Isco, in sensational form tonight, nutmegs an Italian midfielder and plays an excellent ball through to Dani Carvajal. Only a good stop by Italy legend Gianluigi Buffon denies him a goal.