The trap door has already opened on Huddersfield and Fulham.

There is one place left.

Cardiff are the team in trouble, five points from safety, albeit with a game in hand.

They face Burnley today - a proper six-pointer.

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So Spurs could be without their talisman Harry Kane for the rest of the season.

And he could also miss England's Nations League finals in June.

How big a loss will he be for club and country? Who should lead the line for England and how should they set up in his absence?

What player could your team not do without?

Get involved with all your thoughts and tweet #bbcfootball or text 81111.

Stephen Brown: Nuno for me as manger of the season, not just because Wolves have got into a great position but because they play bloody good football against everyone. Rarely set up to defend and break.

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England captain Harry Kane suffered a serious ankle injury against Manchester City.

The medical term is "significant lateral ligament" damage.

Tottenham boss Mauricio Pochettino said it will be "difficult" for Kane to play again this season.

A huge blow for club and country.

To compound Tottenham's problems, Dele Alli fractured his left hand during the match and is a doubt to face Huddersfield today.

Image source, Getty Images

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Tottenham beat Manchester City 1-0 on Tuesday in the first-leg of their Champions League quarter-final.

A huge result for Mauricio Pochettino's side.

But it came at a cost...

The race for the top four is very much alive.

With Chelsea, Spurs, Arsenal and Manchester United all in contention.

Spurs got back to winning ways at their new home with a 2-0 win against Crystal Palace.

A win today is vital. There can be no slip-ups at this stage.

But will they have one eye on Wednesday's Champions League quarter-final second leg against Manchester City?

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I know Jurgen Klopp is going to be many people's favourite for manager of the year regardless of whether Liverpool win the title or not.

But you have to say that the likes of Rafael Benitez, Javi Gracia, Chris Hughton etc deserve plenty of plaudits for what they have achieved.

Newcastle took a huge stride towards safety with a 1-0 win at Leicester.

Ayoze Perez scored the winner, which leaves Rafael Benitez's side 10 points clear of the relegation zone.

You can read the match report here.

Image source, Reuters

Welcome to another weekend of Premier League football.

This is the business end of the season.

On Sunday leaders Liverpool host Chelsea and second-placed Manchester City are at Crystal Palace.

There is just a shade of 2014 about those fixture - more on that later.

But today the battle for a top-four spot and avoiding the final relegation place is at the top of our agenda.

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Six games left.

Everything to play for.

It's survival of the fittest.

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