United have had two penalties shootouts previously in the FA Cup.

They lost on both occasions.

All over.

A heroic performance from Middlesbrough sees them hold out and take the game to penalties.

Bruno Fernandes' corner is helped back towards his by Harry Maguire.

The Portuguese smashes it back in but Phil Jones cannot divert his header on target.

Corner for United in the final minute.

Fred cross but Cristiano Ronaldo cannot control.

United are being forced backwards.

Two minutes added on in extra-time.

One more chance for Manchester United?

Ralf Rangnick's side come once more...

Good save from Joe Lumley, staying alert to tip Scott McTominay's header over the bar.

A change for Boro as Sol Bamba replaces Isaiah Jones.

Alex Bruce
Former Hull defender on BBC Radio Manchester

Middlesbrough can be proud of their performance. They have defended well and attacked when they needed to.

Boro continue to hold out and are taking their time over every goal kick, free-kick and throw-in.

"Attack, attack, attack attack attack," is what the United fans are baying for.

Four minutes to find a winner.

WHAT A CHANCE!

Boro can win it when Aaron Connolly sneaks in, stretching out a divert a shot on goal, but Dean Henderson makes himself big ala Peter Schmeichel to keep the ball out.

Big save from United's number two.

The heavens have opened and it is lashing it down at Old Trafford.

Fred booked for a foul on Aaron Connolly.

Penalties looming large.

Brilliant delivery from Marcus Tavernier and a vital header at the back post from Harry Maguire.

Marcus Tavernier's deep cross is headed across goal by Dael Fry and out of play for a corner off Phil Jones' head.

Now then.

Middlesbrough have a free-kick deep in the United half, can they make it count?

Peter Humfrey: Everyone talking about the handball but with a lineup containing Ronaldo, Pogba, Sancho, Bruno Fernandes, Rashford and Varane really should be out of sight by now. Blame the ref but why aren't United putting 3 or 4 past them?

Imagine if Cristiano Ronaldo steps up in the shootout and misses again.

Wave after wave of Manchester United attack, they are battering at the door but cannot break it down.