Chris Sutton
Former Blackburn striker on BBC Radio 5 Live

The biggest thing for Liverpool is not to concede. This is going to be a tall order but there has to be an element of balance to the way Liverpool play because Real Madrid have players that can pick you off.

Image source, Getty Images

Real Madrid boss Carlo Ancelotti has told his side "not to assume" they are through and Liverpool will try to make it "an open match".

"We have to do both things, attacking and defending, properly. We will not just defend, we are thinking about the attack," he added.

"From a psychological level, the match is more complex for us than Liverpool.

"Liverpool come here to give it their all and do their best from minute one, whatever happens. We saw that from the first leg.

"We will try to do all we can from the beginning but we have more questions than the opponent."

Image source, Getty Images

Erling Haaland had a good night, didn't he?

He scored five goals in City's 7-0 thrashing of RB Leipzig on Tuesday, securing their place in the quarter-finals.

And Haaland says he was brought to Manchester City to help them win the Champions League.

"Of course the club want to win the Champions League," said Haaland.

"They've won four out of the last five Premier League titles. They didn't bring me in to win the Premier League because they already know how to win it.

"So, you can read between the lines. I'm here to try to help the club develop even more and to win the Champions League for the first time."

The Anfield Wrap's Josh Sexton says Liverpool's history in the Champions League means a comeback against Real Madrid is possible, although unlikely.

He told BBC Radio 5 Live's Football Daily: "At this stage it’s improbable, but I’d still say possible.

"You saw at Anfield in the first leg how composed Real Madrid are. Liverpool need to put in a near perfect performance over 90 minutes."

Luciano Spalletti makes two changes to the Napoli side that won the first leg 2-0 in Frankfurt.

Mario Rui and Matteo Politano come in for Mathias Olivera and Hirbving Lozano.

Napoli XI: Meret, Di Lorenzo, Rrahmani, Kim, Rui; Anguissa, Lobotka, Zielinski; Politano, Kvaratskhelia, Osimhen.

Subs: Idasiak, Gollini, Juan Jesus, Elmas, Lozano, Olivera, Simeone, Bereszynski, Ostigard, Gaetano, Ndombele.

Image source, BBC Sport

There are four changes to the Eintracht Frankfurt team from the first encounter.

Randal Kolo Muani is suspended after his red card in Frankfurt with Kristijan Jakic, Philipp Max and Jesper Lindstrom also dropping out.

In come Christopher Lenz, Sebastien Rode, Ansgar Knauff and Rafael Borre.

Eintracht Frankfurt XI:Trapp; Buta, Tuta, N'Dicka, Lenz; Rode, Sow; Knauff; Gotze, Kamada; Borre.

Subs: Ramaj, Horz, Smolcic, Jakic, Alidou, Toure, Hasebe, Alario, Chandler, Max.

Image source, BBC Sport

BBC Radio 5 Live

Mark Chapman is presenting build-up to tonight's game over on BBC Radio 5 Live now. There's full commentary from kick-off.

Chris Sutton
Former Blackburn striker on BBC Radio 5 Live

Liverpool have to believe they can do it. In many respects, they have to have a strong end to the season. In many ways the pressure is off.

I think the last couple of games have typified Liverpool's season. Once again I thought they turned a corner beating Manchester United by seven, then they go to Bournemouth and put in an inspid display.

Now they come to Madrid with a huge deficit. The first goal will be key. I think Liverpool will score on the evening, the question is can they keep this really talented Madrid team out?

The odds are stacked against them. Nobody expects Liverpool to get a result but they know it's within them. Everything has to go right on the night, so I am going to say it is possible.

It's a huge ask for Liverpool to overturn a 5-2 deficit at the Bernabeu but Jurgen Klopp still has hope.

He says that even "if there's only a 1% chance" of his side progressing they "would like to give it a try".

"I said three weeks ago, Madrid with their result, are through to the next round," said Klopp.

"Now we are here three weeks later and we know there's a game to play.

"We're here to play an extremely strong opponent and try to win the game. As difficult as it is, it's not likely, but possible."

Eintracht Frankfurt fans have clashed with police in Italy ahead of their Champions League tie against Napoli.

The Naples government had decided to ban residents of the German city from buying tickets for the match, after violence during the first leg in Frankfurt.

Read more here.

Lots of football going on tonight.

Napoli take on Eintracht Frankfurt with a 2-0 aggregate lead in the other Champions League last-16 tie.

In the Premier League, Southampton host Brentford and Brighton are at home to Crystal Palace - both matches kick-off at 19:30 GMT.

There's also a big game at the bottom of the Women's Super League at 19:00 GMT as managerless Tottenham host Leicester City.

Two changes for Liverpool from the team who lost to Bournemouth.

James Milner comes in for Stefan Bajcetic, who has a thigh injury. Jordan Henderson is ill.

Diogo Jota replaces Harvey Elliott in the other change - so four forwards starting.

Liverpool XI: Alisson, Alexander-Arnold, Konate, Van Dijk, Robertson, Fabinho, Milner, Jota, Salah, Gakpo, Nunez.

Subs: Adrian, Kelleher, Gomez, Keita, Firmino, Oxlade-Chamberlain, Jones, Elliott, Tsimikas, Carvalho, Matip, Williams.

Real Madrid make two changes from the side who beat Espanyol at the weekend.

Karim Benzema returns from an ankle problem to take the place of Rodrygo and Antonio Rudiger replaces Aurelin Tchouameni.

Real Madrid XI: Courtois, Carvajal, Militao, Rudiger, Nacho Camavinga, Modric, Kroos, Valverde, Vinicius, Benzema.

Subs: Lunin, Vallejo, Hazard, Asensio, Odriozola, Vazquez, Tchouameni, Ceballos, Rodrygo, Mendy, Mariano, Alvaro.

Image source, Getty Images

It won't be easy.

Liverpool, last year's finalists, are looking to reach the Champions League quarter-finals but they have some serious work to do.

Defending champions Real Madrid stand in their way with a 5-2 aggregate lead at the Bernabeu.

It looks like 'mission impossible' for the Reds - but can they make it possible?

If they do, it will be a historic night in Europe...