Exeter go top with 32-17 win over Newcastle
Wasps beat Leicester 36-24 to go third
Northampton go fourth with 26-11 win over Sale
Worcester beat Gloucester 28-20 for back-to-back wins
London Irish face Saracens in New Jersey later (20:00 GMT)
Leicester stall Christian Wade down the right on the back of a period of possession, a big tackle to make on the England winger.
10 to go here. It's been a cracking encounter but Wasps will go above their opponents as it stands.
Northampton 21-11 Sale
Excellent defence from 14-man Sale as they repel phase after phase of Saints attacks and win a turnover.
Worcester 25-20 Gloucester
Just five points in it now at Sixways as the artful James Hook twists and neatly jinks his way over, before adding his second conversion to take his individual haul for the day to 15 points. Just 13 minutes left.
The post-George Smith injury passage of play has been sloppy.
Kick-tennis forces a knock on by Dan Robson, but Leicester hand over possession having infringed at the scrum.
Wasps get field position from the penalty and will look for a catch and drive here...
Worcester 25-13 Gloucester
A second penalty for Tom Heathcote restores Warriors' 12-point advantage with just 15 minutes left..
Relief all round the Ricoh Arena as George Smith is helped off the field under his own steam.
Looked serious but he's walking and moving fine.
Big loss for the Wasps though that's the least of their concerns given the potential for injury just there.
Exeter have tried to get Henry Slade involved in this game and he's shown little flashes of brilliance.
Falcons currently holding on.
Wasps' afternoon might just have soured a bit here, with the clock stopped, George Smith is currently down after landing awkwardly.
The longer the break goes on, the more concerning the situation becomes.
It's a break that has stopped the flow of a really enjoyable and open game, despite the scoreline.
Worcester 22-13 Gloucester
Worcester are penalised for obstruction and James Hook immediately reduces the gap to nine points with his second successful penalty.
Northampton 21-11 Sale
Northampton's George Pisi is sin-binned for tripping a Sale runner as he was trying to get to the ball.
Wasps 36-17 Leicester Tigers
Image source, Getty ImagesGame over perhaps? Brilliant work by Wasps who shift the ball from right to left, Dan Robson finds Ashley Johnson, who drove forward.
Nathan Hughes finished it off with his bustle across - too much power - and Alex Lozowski might just have hammered the nail in the coffin with his conversion.
Worcester 22-10 Gloucester
Scrum-half Francois Hougaard is awarded a try at the base of the posts following consultation with the TMO. But much doubt exists over the scorer.It has also been credited to Niall Annett. The one sure thing is that Heathcote has added the extras.
Image source, Getty ImagesFirst points at the game, Nili Latu pulled for a deliberate knock-on and Gareth Steenson clips over the kick to put Rob Baxter's Premiership title chasers in front.
10 minutes into the second half and back to 15 men a side following the return of Gloucester loose forward Moriarty, but Worcester are still looking the more likely of the two sides to score again
Nathan Hughes has come on for Wasps, he could be a blockbusting addition to the side here this afternoon.
Raking kick from Dan Robson has bobbled into touch in the Tigers 22... Mathew Tait failed to cope with it and the visitors are penned back in their own end-zone.
Northampton 21-11 Sale
Tom Collins goes over for a second try in as many minutes after a wonderful offload from Lee Dickson after he had broken through the Sale line. Stephen Myler converts.
Newcastle Falcons will be pleased with their start at Sandy Park.
They've competed well at the breakdown in the first stages, and stemmed the Chiefs attack so far.
No score so far, with seven minutes on the board.
Northampton 14-11 Sale
Ken Pisi goes over down the left after a very patient build-up from Northampton. Saints, who for much of the first half were seocnd-best, have certainly shifted up a gear in the second period. Stephen Myler adds the extras.
Not great news for Wasps with Jimmy Gopperth off, having taken a poke in the eye.
Tigers send on Fraser Balmain for Logovi'i Vunipola, a well-earned break for him.
Exeter Chiefs 0-0 Newcastle Falcons
We're under way at Sandy Park. Important game for two very different reasons at separate ends of the table.