New surroundingspublished at 16:27 Greenwich Mean Time 10 February
England v Wales (16:45 GMT)
Will Immanuel Fey-Waboso and Chandler Cunningham-South get their chance to play on the hallowed Twickenham turf?
England fight back to beat Wales and go top of Six Nations with two wins from two
Wales put in another huge effort but suffer second narrow defeat
George Ford penalty gave England lead in final 10 minutes at Twickenham
Fraser Dingwall try cut Wales' lead to 14-13 in second half
Penalty try and Alex Mann try gave Wales 14-5 half-time lead
Ben Earl powered over for England but George Ford conversion charged down
Alastair Telfer
England v Wales (16:45 GMT)
Will Immanuel Fey-Waboso and Chandler Cunningham-South get their chance to play on the hallowed Twickenham turf?
England v Wales (16:45 GMT)
England have named an unchanged starting XV for the game against Wales.
It is the first time England have fielded an unchanged starting team since the World Cup final in 2019.
In the one change to the squad from the win in Italy, vice-captain Ellis Genge returns from injury to make the bench.
"We're delighted to be back playing in front of a sold-out Twickenham Stadium this Saturday," said head coach Steve Borthwick.
England: Steward; Freeman, Slade, Dingwall, Daly; Ford, Mitchell; Marler, George (capt), Stuart, Itoje, Chessum, Roots, Underhill, Earl.
Replacements: Dan, Genge, Cole, Coles, Cunningham-South, Care, F Smith, Feyi-Waboso.
England v Wales (16:45 GMT)
Mantej Mann
BBC Sport at Twickenham
Jamie George spoke about the emotion he will feel at leading England out for the first time at Twickenham as captain.
The hooker, whose reign as skipper began in Rome, looked focused as he marched his team deep inside the bowels of Twickenham.
His team's arrival was met by a large crowd of passionate supporters - a sign of what is to come inside the ground, perhaps?
England v Wales (16:45 GMT)
England captain Jamie George wants to make Twickenham "great again" as he leads out the team for the first time in a Six Nations match at Twickenham.
Steve Borthwick’s side have won two out of their last six games at home - the last being a World Cup warm-up defeat by Fiji.
"Our recent record at Twickenham has been poor and we have been very outspoken about how we want Twickenham to be great again," George told Rugby Union Daily.
"We have extended the walk [to the stadium] from the bus and there have been changes in the changing room, which will hopefully make a difference to the team.
"That especially for young fans is what they want and there has been changes in the changing room which are in-house.
"There will also be a few bits with breaks in play for the music that is played."
England v Wales (16:45 GMT)
England v Wales (16:45 GMT)
Mantej Mann
BBC Sport at Twickenham
It may be a fierce rivalry on the pitch but England fans Brenda and Lauren were full of praise for the friendly atmosphere before kick-off.
Lauren said: "The atmosphere here today has been electric since the gates opened at 13:15 (GMT) this afternoon. We're getting ready to shout for the team. It is also so wonderful to see a nice mix of Wales and England fans and the good feeling between them."
Brenda added: "We just spent an hour in the company of a Welsh fan and we all hugged. It was fantastic."
England v Wales (16:45 GMT)
Former Wales captain. Wales legend.
Has predicted ENGLAND to win!
England v Wales (16:45 GMT)
Philippa Tuttiett
Former Wales international on BBC Radio 5 Live
George North has pretty much seen and done everything. His physical stature will be a massive aid.
If you look across the backline it is not the biggest. Nick Tompkins manages to get gainline with his feet rather than his physical presence.
Having an option of a crashball with North gives another dynamic to their attack, but also to be that chat into Ioan Llyod, as if you think Sam Costelow was fresh-faced Lloyd looks about 10 years younger again, in his first Six Nations start at Twickenham.
Having the bookends of Tomos Williams - incredibly experienced scrum-half - and having that chat from the outside with George North is huge.
That centre partnership of Tompkins and North out of the whole Welsh team is the pairing we are hinging on the most. The most consistent pairing.
England v Wales (16:45 GMT)
Sam Harris
BBC Newsbeat sports reporter
Wales captain Dafyyd Jenkins combines life with the Exeter Chiefs with that of being a student at the University of Exeter, where he is studying Sports Science.
"Daf is intense, but he's a real character in the changing room," Kofi Barton-Byfield, who played with Jenkins for the university side, said.
"He sets the standards wherever he goes and wherever he plays."
Jared Williams, who's also Welsh and plays for the side, added: "I remember in a BUCS game against Bath where we were losing, he went and disturbed their team, grabbing all their water bottles.
"It disrupted them and we ended up going on to win, it spurred the boys on."
England v Wales (16:45 GMT)
George North returns from injury to play for Wales as one of seven changes to the team beaten by Scotland.
The fit-again centre will be making his 50th Six Nations appearance.
Ioan Lloyd and Tomos Williams, who helped spark last weekend's comeback in the 27-26 defeat by Scotland, are rewarded with starts.
The entire starting front-row changes with Gareth Thomas, Elliot Dee and Keiron Assiratti all selected.
Flanker Alex Mann, who scored a try against Scotland, gets his first Test start.
Wales: Winnett; Dyer, North, Tompkins, Adams; Lloyd, Williams; G Thomas, Dee, Assiratti, Jenkins (capt), Beard, Mann, Reffell, Wainwright.
Replacements: Elias, Domachowski, Griffin, Rowlands, Basham, Hardy, Evans, Grady.
England v Wales (16:45 GMT)
New Wales captain Dafydd Jenkins might still be an international rugby novice but he knows what is at stake against England.
Jenkins, 21, became Wales' second-youngest captain after Sir Gareth Edwards last weekend, leading Wales in the narrow 27-26 defeat by Scotland.
"I wouldn't say it's like any other game because England and Wales is special," said Jenkins.
"There's massive history behind the game. It's a must-win game for us because of the place we are in the tournament.
"It'll be the best place to win. For a Welshman there's no better place especially playing over there, if you win over there you gain a lot of respect from them. It's huge for us.
"It was a dream last week to lead Wales but it will be a lot better if we win."
England v Wales (16:45 GMT)
Matt Dawson
2003 World Cup winner on BBC Radio 5 Live
The system has to be practical and doable. We could all say get off the line faster, faster, faster and press harder.
But if you are losing the control of your body and your movement towards what the opposition are doing in attack, then you could get off the line as fast as you like, but you are not going to be able to make those decisions.
Unfortunately, the margin for error and the way England are trying to defend is going to be huge. If they are going to run up that quickly your instinct and reaction is never going to be good enough to change, as you would if you were at 70% with that split second to think.
Practically it has to work as well as emotionally with the idea of a hard press.
England v Wales (16:45 GMT)
South Africa's World Cup-winning coach Jacques Nienaber said it took 14 games for the Springboks to adjust to their new defensive system.
In that time they lost 50% of their games. But South Africa only lost once in 2019 and won the World Cup.
Felix Jones, who was part of two successful World Cup campaigns with South Africa, was in charge of fine-tuning their successful blitz defence for their World Cup victory in 2023.
Now in charge of England's defence, it was clear from the opening weekend he wants to employ a similar system.
After Italy opened up the system on multiple occasions for tries, will there be holes for the dangerous Wales backline to exploit?
England v Wales (16:45 GMT)
Scotland survived a stunning comeback from Wales to hang on for a nail-biting first victory in Cardiff for 22 years.
Wales started their campaign with one of their poorest 40 minutes in recent memory, but showed heart in the second period to show their young talent has potential.
England v Wales (16:45 GMT)
England edged out a 27-24 victory against an impressive Italy to open their Six Nations campaign in Rome.
It was Steve Borthwick's side's first opening win of the Six Nations since against Ireland in 2019.
England v Wales (16:45 GMT)
While France and Scotland are finishing up at Murrayfield.
Next up is one of the oldest rivalries in the game as England host Wales at Twickenham.
It was far from perfect from both sides during the opening weekend of the championship, but form and history does not matter in this one.
England v Wales is usually one to remember! Kick-off is at 16:45 GMT.