Serena Williams retires injured at 3-3 in first set against Aliaksandra Sasnovich
Williams appeared to be hurt when losing her footing in fifth game of match on Centre Court
Roger Federer into second round after Adrian Mannarino retires one point into final set
Mannarino could not continue after slipping on court late in fourth set - also on Centre Court
Nick Kyrgios v Ugo Humbert 3-3 in final set when 23:00 BST curfew ends play on day two
Coco Gauff beats GB's Francesca Jones 7-5 6-4
Top seed Ashleigh Barty overcomes Carla Suarez Navarro 6-1 6-7 (1-7) 6-1
Dan Evans defeats Feliciano Lopez 7-6 (7-4) 6-2 7-5
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Tim Henman
Former British number one on BBC Two
Mannarino really put in a fantastic performance and then so unfortunate to see that slip and the knee injury.
We thought it was going to be an amazing birthday present to come out on top of Federer at Wimbledon.
It's really not the finish we hoped for.
Image source, Getty Images
*Federer 6-4 6-7 (3-7) 3-6 6-2 Mannarino
Adrian Mannarino cannot continue, you have to feel for him, the Frenchman retires after that knee injury in the fourth set and Roger Federer is through.
Federer goes through after Mannarino retires
Jo Durie
Former British number one on BBC TV
Gauff looks so at home on a big court. Two years ago she just coped with everything.
Maybe the lockdown etc has taken the pressure off and she's had time to develop and mature, because it was all coming at her in a rush.
So skillful, so good... and so young.
Federer 6-4 6-7 (3-7) 3-6 6-2 Mannarino
Corrr. For a man struggling that's a sensational backhand winner. Two set points to go. And Federer takes it on the next. It's two sets a piece.
Federer 6-4 6-7 (3-7) 3-6 5-2 Mannarino*
Mannarino probably just wants to get to the end of this set - Federer has three set points.
*Jones 5-7 Gauff
Katie Falkingham
BBC Sport at Wimbledon
It's advantage Coco Gauff in the first set. She finally breaks Fran Jones' serve after four failed attempts.
It's easy hold next and that's the first set to the American.
Image source, Getty Images
Jonathan Jurejko
BBC Sport at Wimbledon
Poor Adrian Mannarino. He looks close to tears. The Wimbledon crowd try to gee him up after the first double fault, somehow he manages a smile after the second.
Only the stone hearted can't feel for the guy.
Federer 6-4 6-7 (3-7) 3-6 5-2 Mannarino*
Adrian Mannarino isn't happy, he's still trying to walk off that knee injury, but looks to be struggling. The Frenchman thinks he's served double fault but hasn't and has to wander back to the other side of the baseline. He then does knock down a double, he's trying to laugh but obviously hurting.
*Struff 4-6 6-1 2-3 Medvedev
John McEnroe
Three-time Wimbledon singles champion on BBC TV
This crowd must be loving this. Medvedev has hit a few shots you don't expect to see players hitting.
Federer 6-4 6-7 (3-7) 3-6 5-2 Mannarino*
Lovely sweeping forehand winner from Roger Federer with Adrian Mannarino still a little tentative at the other end, understandably. The Swiss holds.
Jonathan Jurejko
BBC Sport at Wimbledon
Huge roar of support as Adrian Mannarino jogs back to the baseline to resume. The Frenchman doesn't look entirely comfortable to me, but let's hope he can get through to the end and do no further damage.
*Federer 6-4 6-7 (3-7) 3-6 4-2 Mannarino
Adrian Mannarino is back to his feet and wandering over to the baseline, to plenty of applause from the Centre Court crowd.
Shapovalov 6-4 4-6 6-3 5-7 6-4 Kohlschreiber
After five sets in over three and a half hours, 10th seed Denis Shapovalov has secured his place in the second round.
The Canadian serves out the match to beat German Philipp Kohlschreiber 6-4 4-6 6-3 5-7 6-4.
He'll meet Frenchman Pierre-Hugues Herbert or Spain's Pablo Andujar next, before potentially facing Britain's Andy Murray in round three.
*Federer 6-4 6-7 (3-7) 3-6 4-2 Mannarino
Well, Adrian Mannarino walks to his chair to be assessed, which is a good sign.
Chris Bradnam
BBC Sport commentator at Wimbledon
Really nasty - his knee just buckled inwards. The way he stayed down and the way he's been grimacing - physio coming
Image source, Getty ImagesJonathan Jurejko
BBC Sport at Wimbledon
Oh no, awful to see this. Adrian Mannarino looks in big trouble after going down and holding his knee. A hush on Centre Court, with Federer going over to see how his opponent is. Fingers crossed he can continue.
*Federer 6-4 6-7 (3-7) 3-6 4-2 Mannarino
Ah, that didn't look too good, Adrian Mannarino slips while trying to change direction and goes down on the Centre Court turf. Let's hope the Frenchman is OK. He's called for the physio.
*Federer 6-4 6-7 (3-7) 3-6 4-2 Mannarino
And Mannarino holds to stay within touching distance.
Federer 6-4 6-7 (3-7) 3-6 4-1 Mannarino*
Snappy ace from Adrian Mannarino and fends off the break to move to deuce.
Federer 6-4 6-7 (3-7) 3-6 4-1 Mannarino*
We're talking millimetres now. Adrian Mannarino cups a backhand into the tramlines and Roger Federer has break point.