All Blacks star Jordie Barrett takes over from Robbie Henshaw at centre with Furlong drafted into a totally changed front row from last weekend's 62-0 win over Harlequins.

Barrett was a replacement in the thumping last-16 victory over the English club.

Henshaw will make his 100th Leinster appearance if he is introduced from the bench on Friday night while the other backs change has Timmy O'Brien handed his first European start as he takes over from Jamie Osborne.

Tadhg Furlong, who came on as a replacement against Harlequins in his first Leinster appearance since October following a lengthy injury spell, will start in the front row alongside Cian Healy and Ronan Kelleher with Andrew Porter, Dan Sheehan and Rabah Slimani dropping to the bench.

Max Deegan is named in the back row in place of Caelan Doris as Jack Conan skippers Leo Cullen's side.

Leinster's second row is unchanged with Joe McCarthy again partnered by South Africa World Cup winner RG Snyman.

Lock Diarmuid Mangan will make his European debut if he is introduced from the bench.

Leinster: Keenan; T O'Brien, Ringrose, Barrett, Lowe; Prendergast, Gibson-Park; Healy, Kelleher, Furlong; McCarthy, RG Snyman; Deegan, Van der Flier, Conan (capt).

Replacements: Sheehan, Porter, Slimani, Mangan, Doris, McGrath, R Byrne, Henshaw.

Game faces on. I wonder what the tunes of choice are to get you pumped up for a game of this magnitude?

Image source, Getty Images

Image source, Inpho

Image source, Getty Images

Glasgow hooker Johnny Matthews told the BBC's Scotland Rugby Podcast: "It's always good when you can put that amount of points on a team that's going very well on the Premiership and still be disappointed with some areas of the game.

"One of Franco's main things is we don't have to lose to learn. We're still always trying to improve and still always trying to get better.

"You look at Leinster in the URC this season. They've set the standard and, historically, they might not have won the Champions Cup in the past few years, but they're always there or thereabouts and they're always one of the names in the mix.

"They have probably one of the most stacked teams in the world, certainly in the URC and in Europe. They're all world-class players.

"But we feel we've got the right tools to take them down. It's going to be a really good challenge for us, but we want to relish it and we can't wait to get stuck into them on Friday."

Glasgow make three changes from the win over Leicester which included Scotland prop Zander Fagerson missing out with concussion as he is replaced by Sam Talakai.

Alex Samuel is preferred to JP du Preez in the second row while the suspension of Henco Venter leads to a back row reshuffle as Rory Darge comes into the team at openside flanker, with Sione Vailanu switching to number eight.

Max Williamson could make his long-awaited return from injury off the bench for the Warriors.

However, the Warriors are without star centres Sione Tuipulotu and Huw Jones, and influential forwards Scott Cummings and Jack Dempsey.

Glasgow Warriors: Rowe, Dobie, McDowall, Jordan, Steyn, Hastings, Horne; McBeth, Matthews, Talakai, Brown, Samuel, M Fagerson, Darge, Vailanu.

Replacements: Stewart, Bhatti, Schickerling, Du Preez, Williamson, Ferrie, Afshar, Cancelliere.

Image source, Getty Images

Glasgow have had a strong campaign in Europe so far and booked their place in the quarter-finals with a 43-19 victory over Leicester Tigers at Scotstoun.

Henco Venter and Sione Vailanu both scored two tries, while George Horne and Adam Hastings also touched down for the hosts.

In the pool stages, Franco Smith's side finished second behind Toulon, with two victories from their four matches.

Glasgow started with a big win over Sale Sharks, but lost by a single point in Toulon in their second fixture.

They got the better of Racing 92 in their penultimate match, and rounded out the Pool stage with a defeat away to Harlequins.

Image source, Getty Images

Leinster's European campaign has been close to perfection to far.

Their status as one of the favourites to lift the trophy in Cardiff next month was underlined by their last-16 win over Harlequins.

James Lowe scored two tries in the 62-0 victory in Dublin, with the rest of the tries spread out around the team.

Leo Cullen's side won all four of their Pool fixtures - against Bristol Bears, Clermont, La Rochelle and Bath - and were pipped to top seeding by Bordeaux, who claimed two additional bonus points.

We're into the quarter-final stage of the Investec Champions Cup and we've four very tasty matches for you this weekend.

• Leinster v Glasgow Warriors (Friday, 20:00 BST)
• Bordeaux v Munster (Saturday, 15:00 BST)
• Northampton v Castres (Saturday, 17:30 BST)
• Toulon v Toulouse (Sunday, 15:00 BST)

Leinster v Glasgow is a tasty appetiser for the weekend, and Munster will look to pull off another big victory in France against Bordeaux.

Northampton are the last English team standing and host Castres later on Saturday.

The all-French tie between Toulon and Toulouse is a barnstorming way to round out the weekend.

Here's a comparison between the sides in their five European matches this season.

Image source, Getty Images

Image source, Inpho

It's time for the busniess end of the Investec Champions Cup with a place in the semi-finals up for grabs.

First up, it's favourites Leinster against Glasgow Warriors in the opening last-eight tie and it should be a cracker in Dublin.

Leinster are regulars at this stage while Glasgow are looking to reach the last four for the first time.

The prize on offer is a semi-final tie against either Northampton or Castres.

We'll have live updates of the game right here, so we'll have you covered!