First images of the scenepublished at 10:51 BSTBreaking
We're getting the first images from the scene of the incident now - we'll bring you more in the next few moments.
Image source, PA MediaSummary
Counter-terrorism police are about to give an update after two people died in a car and stabbing attack at a synagogue in Manchester - watch it live above
A third person, the suspect, died after being shot by police, while three other people are in a serious condition
"Get back, he has a bomb!" Video shows police warning the public - with a picture showing a man with items round his waist
Police say a "large number of people" were worshipping at the Heaton Park synagogue - today is Yom Kippur, the holiest day in the Jewish calendar
One witness tells the BBC the police gave the suspect "a couple of warnings - he didn't listen so they opened fire"
Keir Starmer ends a trip to Denmark early, and says extra police will be deployed at synagogues across the country
First images of the scenepublished at 10:51 BST
Image source, PA MediaOffender 'believed' to be dead, Burnham sayspublished at 10:46 BST
We're hearing more detail now from Greater Manchester Mayor Andy Burnham, who's been speaking to BBC Radio Manchester.
Burnham says "it is believed" that the offender is deceased, but says this "is not confirmed".
We'll bring you more on this as soon as we have it.
Witness saw car driving towards public: Police give more detail on attackpublished at 10:43 BST
BreakingWe've just had the following statement from Greater Manchester Police, giving more details on the incident:
"Police were called to the Heaton Park Hebrew Congregation Synagogue, on Middleton Road, Crumpsall, at 9:31am by a member of the public, stating he had witnessed a car being driven towards members of the public, and one man had been stabbed.
"GMP declared PLATO and a major incident at 9:37am. Shots were fired by Greater Manchester Police firearms officers at 9:38am. One man has been shot, believed to be the offender.
"Paramedics arrived at the scene at 9:41 and are tending to members of the public, currently four members of the public with injuries caused by both the vehicle and stab wounds.
"Members of the public are asked to avoid the area while the police continue to deal with the incident."
Four people injuredpublished at 10:40 BST
BreakingFour people have been injured in the attack.
Suspect has been shot, police saypublished at 10:38 BST
Daniel Sandford
BBC NewsGreater Manchester Police has confirmed that the suspect in the Crumpsall synagogue attack has been shot.
The force was not able to say what their condition is.
Incident at synagogue comes on Yom Kippurpublished at 10:34 BST
The incident in Manchester comes on Yom Kippur - the holiest day in the Jewish religious calendar.
Large numbers of Jewish people attend synagogues and fast on this day.
Ambulance service declares major incidentpublished at 10:30 BST
BreakingThe North West Ambulance Service has just put out a statement, confirming a major incident has been declared in Crumpsall, Manchester.
It says:
"Following reports of an incident on Middleton Road in Crumpsall, the trust has dispatched resources to the scene.
"We are currently assessing the situation and working with other members of the emergency services.
"Our priority is to ensure people receive the medical help they need as quickly as possible."
Immediate danger seems to be over - Burnhampublished at 10:28 BST
Some more now from Greater Manchester Mayor Andy Burnham, who advises listeners to "avoid the area".
"At the same time, I can give some assurance that the immediate danger appears to be over," he adds.
He says the incident was dealt with "effectively" by those on site, and by Greater Manchester Police.
Manchester mayor Burnham says it's 'serious incident'published at 10:26 BST
BreakingWe're hearing now from Andy Burnham, the mayor of Greater Manchester, who tells the BBC what's happened is a "serious incident".
He's speaking to BBC Radio Manchester - stick with us for more lines.
Multiple people stabbed - policepublished at 10:22 BST
BreakingA bit more now from police, who say they believe multiple people have been stabbed.
We'll bring you more details as soon as we have them.
Police at scene of reported stabbing at synagoguepublished at 10:21 BST
BreakingGreater Manchester Police say they are at the scene of a reported stabbing at a synagogue in Crumpsall.
Police dealing with incident in Manchesterpublished at 10:20 BST
BreakingPolice are dealing with an incident in Manchester.
This is a breaking story and lots is unclear, but we'll have more for you in the next few moments.