The UK has voted to leave the European Union after 43 years
David Cameron announces he will resign as prime minister
Leave won by 51.9% to 48.1%
East of England votes to Leave by nearly 57% to 43%
Every district in Suffolk and Essex votes Leave
In eastern half of the region, only Cambridge, South Cambs and Norwich vote Remain
In reaction to the news, the value of the pound fell to its lowest level since 1985
All the results from across the East of England have now been declared with a clear victory for Brexit and only four of our council areas voting to Remain.
In the East (not including Northants or Milton Keynes) 56% of people voted to leave the EU, with 44% wanting to Remain.
The total number of votes for Leave was 1,880,367, while Remain got 1,448,616.
That's it. All the results are in.
UKIP's candidate for Cambridgeshire's police and crime commissioner role, Nick Clarke, has tweeted to say today is a historic moment.
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UKIP leader Nigel Farage has been speaking on BBC Essex's James Whale Breakfast Show this morning about victory for Brexit.
"If you have a dream in life, when it comes true it's almost difficult to believe it. But it has happened, and I keep having to pinch myself to remind me it's true", he said.
"It's fantastic. I can't believe it... 25 years of hard work and and a decade of being demonised by the media and political class - it has all been worth it for the feeling this morning."
BBC political editor Laura Kuenssber, externalg has this insight:
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Jack Warren
BBC Local Live
I spent the night at the Eastern Region Referendum count in Chelmsford. It was my first time at such an event, and as I entered the Riverside Ice and Leisure centre it was filled with excitement, tension and the noise of ballot papers being counted.
I arrived just after midnight. News had trickled in that Nigel Farage had conceded defeat, and those supporting the Remain camp seemed quietly confident.
However, the mood swiftly changed as the first results around the East came through about 01:30 - which soon snowballed into a virtual whitewash for the Leave campaign.
MP for South Suffolk, pro-Remain Conservative James Cartlidge, tweeted earlier to say the vote was a "landslide for Leave".
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It was a clean sweep for Leave in Suffolk with all seven districts declaring for Brexit.
Waveney had the highest proportion of Leave votes at 62.9%, with Suffolk Coastal the keenest to remain with 47% of the votes.
UKIP Essex county councillor for Wickford and Crouch, Nigel Le Gresley, has this message for critics who say the Brexit vote was based on anti-immigration sentiment:
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Bernard Jenkin, the pro-Leave Conservative MP for Harwich and North Essex, says Chancellor George Osborne will need to "start being reassuring" to stablise markets following Britain's decision to leave the EU.
Image source, Conservative Party"The markets are responding to what the Chancellor's told them is going to be a terrible thing," Mr Jenkin said earlier.
"He's got to change tack very quickly and say 'I was wrong, there isn't going to be an earthquake, there isn't going to be a plague of frogs' - he needs to start being reassuring, otherwise he'll be out of a job."
This wasn't the morning Labour MEP Richard Howitt was hoping to wake up to.
Quote MessageWe have to accept that we live in a democracy and respect the rules of the game. I don't believe, however pro-European I may be, that could ever trump the decision of the people in an elected vote."
Richard Howitt, Labour MEP for the East of England
This was what Vote Leave's East regional director had to say as the scale of his campaign's victory became apparent.
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People in Norfolk have overwhelming voted to leave the European Union with only Norwich recording a Remain victory.
This is how the county voted.
Tom Barton
BBC Look East political reporter
We have long known that the East of England is one of the most Eurosceptic parts of Great Britain.
In the past few hours, that fact has shown itself to be overwhelmingly true.
Across Essex and right up the East coast, people voted for Brexit. The same is also true further west with a few notable exceptions, such Norwich and Cambridge.
As the sun rises over Lowestoft this region - just like the rest of Britain - is changed forever.
A jubilant UKIP leader Nigel Farage has been speaking to BBC Essex's James Whale:
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If you're the country's only UKIP MP, today must feel like some achievement.
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BBC Politics
It's official - the UK has voted to leave the European Union.
London and Scotland voted strongly to stay in the EU but the remain vote has been undermined by poor results in the north of England.
Voters in Wales and the English shires have backed Brexit in large numbers.
The pound fell to its lowest level against the dollar since 1985 as the markets reacted to the results.
The East was among the strongest regions for Leave voters. All districts in Essex and Suffolk voted for Brexit.
Just Norwich, Cambridge and South Cambridgeshire in this part of the East voted to remain.
Andrew Sinclair, BBC East political correspondent has tweeted:
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