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Conservative Nigel Evans supported the government's deal, having opposed it in January.

He says: "I fear being trapped in the EU more than I fear being trapped in the backstop."

Mr Evans also questions the point of extending Article 50: "For what? So we can continue arguing for the next few months?"

Adam Fleming
Brussels reporter

BBC's Brussels correspondent Adam Fleming says the EU 27 have legislation going through and there is a growing confidence that "they are prepared to deal with the absolute worst of no-deal".

On the possibility of the extension of Article 50, he says among the EU 27 there is a legally orthodox view that Brexit must be over by the end of May, but others say 2 July.

If the UK stays in after that date, it would either have to take part in the European elections which would be "bizarre", Adam Fleming adds, noting that the other option would be to not send MEPs to Europe, which would be "a massive breach of European law".

"There is very little optimism," he concludes.

Image source, Reuters

Spanish Prime Minister Pedro Sanchez says: “We regret the decision of the British Parliament despite the EU's efforts to achieve the best possible agreement.

"The European project must move forward to ensure freedom, stability and prosperity.

"We need pro-European governments. Let's protect Europe so that Europe will protect us.”

Finnish Prime Minister Juha Sipila says: “The result of the British vote cannot be regretted.

"On the EU side, every effort has been made to reach an agreement.

"If Britain makes a reasoned request for extension, we will discuss it and decide it unanimously in EU27.“

Laura Borland, 35, is a Remainer living in Sunderland who didn’t vote in the referendum

She says: “I can’t believe they’ve not come to some sort of deal so close to 29 March.

"I almost feel like we should have another election, but I wouldn’t know who to vote for.

"We should sack the lot of them.”

BBC News Channel

Image source, HoC

SNP's Westminster Leader Ian Blackford says the prime minister needs to recognise that there is not a majority for her deal after "a second disastrous defeat".

Parliament must accept its responsibility, he says, adding: "The prospect of no-deal is frightening - and we have the responsibility of taking that risk away."

"No-deal is in nobody's interest," Mr Blackford says, and he calls for a "People's Vote".

Mr Blackford says another EU referendum "could happen in the Autumn", but that it would take some time to arrange.

BBC News Channel

The Spectator's deputy political editor, Katy Balls, says the option of a no-deal Brexit does not have a majority in the Commons, although remains the default option.

She notes that Theresa May's Brexit deal defeat this evening was not as heavy as in the first meaningful vote, and could get "back on track".

It is hard to take no-deal off the table, Ms Balls adds, but notes that a no-deal Brexit would be "hard to get to given the force against it - although not impossible".

Stephen Irish is the commercial director of Hyperdrive in Washington, which produces batteries for electric vehicles and works with Nissan

He says: “I’d prefer to have an end to the uncertainty but it doesn’t affect our plans.

"We’re in a green energy sector, which is growing globally.

"We are already looking to manufacture more products outside the EU, like Taiwan and, in the future North America.”

Image source, Reuters

Theresa May's revised Brexit deal has been defeated in the House of Commons as MPs voted against it by 391 to 242, despite last minute assurances over the Irish backstop.

Click here to find out how your MP voted.

Image source, AFP/Getty Images

The CBI has responded to the result of tonight's vote.

Carolyn Fairbairn, the director general of the CBI, said: "Enough is enough. This must be the last day of failed politics.

“A new approach is needed by all parties. Jobs and livelihoods depend on it.

“Extending Article 50 to close the door on a March no-deal is now urgent. It should be as short as realistically possible and backed by a clear plan.

“Conservatives must consign their red lines to history, while Labour must come to the table with a genuine commitment to solutions.

“It’s time for Parliament to stop this circus.”

Laura Kuenssberg
BBC political editor

Image source, Reuters

Second time very unlucky. The tweaks to the deal with the EU that the prime minister sweated for more than a month to achieve were to little purpose.

The government was, again, comprehensively defeated, this time by almost 150 votes.

One senior cabinet minister said this afternoon another thumping defeat would mean that she "has to change course".

In the last few minutes, she has shown no sign of that, repeating, as we have heard her say so very many times at the despatch box, that she believes her deal is still the best one.

But neither did she move away from the promises she has made more recently, to give MPs a vote on whether they want to stop us leaving without a formal deal at the end of this month.

Read more here.

Image source, reuters

Dutch Prime Minister Mark Rutte says: “I regret the outcome of tonight's Brexit vote.

"It is disappointing that the UK government has been unable to ensure a majority for the withdrawal agreement agreed by both parties in November, even after multiple additional assurances from the EU.

"A solution must come from London.

"Should the UK hand in a reasoned request for an extension, I expect a credible and convincing justification.

"The EU 27 will consider the request and decide by unanimity. The smooth functioning of the EU institutions needs to be ensured.”

BBC Radio 5 Live

BBC Radio 5 Live is hearing reaction from listeners after Theresa May's Brexit deal was defeated in the Commons.

Lifelong Labour voter Stephen says he has "lost faith in politics" and will never vote in an election again.

Speaking to 5 Live's Tony Livesey, Stephen said politicians "don't have the right to do this to 17.8 million people".

Fellow caller Sam feels more positive about the result.

"Obviously I want the UK to stay in Europe," he says. "I've taken the opportunities that have been given to me as an EU citizen to live and work in Poland and now in Romania."

Hear all the latest reaction from BBC Radio 5 Live on BBC Sounds.

House of Commons
Parliament

Here is the motion which MPs will vote on tomorrow:

That this house declines to approve leaving the European Union without a withdrawal agreement and a framework on the future relationship on the 29th March 2019, and notes that leaving without a deal remains the default in UK and EU law unless this house and the EU ratify an agreement.

Speaker John Bercow has confirmed that the deadline for submitting amendments to the motion is 10:30 GMT and that votes will be expected at 19:00.

Andrea Leadsom also confirmed that Thursday’s motion will allow MPs to propose the length of extension, saying it “will be an amendable motion so it will be for the House to agree the length of such an extension”.

BBC News Channel

Image source, HoC

Speaking to BBC political correspondent Vicki Young, Conservative MP Suella Braverman says the defeat is a sign that the deal is bad.

She says Theresa May's deal would have given the EU a huge say over the UK's laws, which is not what people voted for in the referendum.

"I am confident with my decision" to vote against the deal, she adds, noting that she will vote to maintain no-deal as an option.

If no-deal is taken off the table, all the leverage is given to the EU, she says.

Image source, Getty Images

The Mayor of London, Sadiq Khan, says: “I welcome tonight’s vote to reject the government’s bad Brexit deal.

“The prime minister needs to put our city and our country first, and withdraw Article 50.

“It’s time to give the British public the final say on Brexit.”