Covid: Vaccines '90% effective' at preventing Delta variant deaths

Vaccination is 90% effective at preventing deaths from the Delta variant of Covid-19, researchers say.

The data, released by the University of Edinburgh, was gathered using a Scotland-wide Covid surveillance tool.

Figures suggest the Pfizer-BioNTech vaccine is 90% effective and the Oxford-AstraZeneca jab 91% effective at preventing deaths.

It looked at people who have been double-vaccinated but who have tested positive for Covid in the community.

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The study is the first to show across an entire country how effective vaccines are at preventing death from the Delta variant, which is the most dominant form of Covid in the UK.

Researchers defined death from Covid as anyone who died within 28 days of a positive PCR test, or with Covid recorded as a cause of death on their death certificate.

The study analysed data from 5.4 million people in Scotland between 1 April and 27 September this year.

During this period, 115,000 people tested positive for Covid using a PCR test in the community, rather than in hospital, and there were 201 Covid-related deaths recorded.

Tracked in real time

No deaths have been recorded in those who have been double-vaccinated with the Moderna vaccine in Scotland, according to the data.

Researchers said it is therefore not possible to estimate this particular vaccine's effectiveness in preventing Covid-related deaths.

The research team from the University of Edinburgh, University of Strathclyde and Public Health Scotland analysed the dataset as part of the EAVE II project - Early Pandemic Evaluation and Enhanced Surveillance of Covid-19.

It uses anonymised, linked-patient data to track the pandemic and the vaccine rollout in real time.

So far, 87.1% of adults in Scotland have taken a second dose of the Covid vaccine.

Third "booster" doses are being offered to everyone over 50, along with frontline medical staff and younger adults with some underlying health conditions.

Prof Aziz Sheikh, director of the University of Edinburgh's Usher Institute and EAVE II study lead, said: "With the Delta variant now the dominant strain in many places worldwide, and posing a higher risk of hospitalisation than previous variants seen in the UK, it is reassuring to see that vaccination offers such high protection from death very shortly after the second dose.

"If you still have not taken up your offer to be vaccinated, I would encourage you to do so based on the clear benefits it offers."

Follow-up studies

Prof Chris Robertson, of the University of Strathclyde and Public Health Scotland, said: "This study shows the value of carrying out analyses of routine healthcare data available in near real-time.

"Our findings are encouraging in showing that the vaccine remains an effective measure in protecting both ourselves and others from death from the most dominant variant of Covid-19."

He added that it was important to validate these early results with follow-up studies.

The team behind the study said due to the observational nature of the figures, data about vaccine effectiveness should be interpreted with caution and said it was not possible to make a direct comparison between both vaccines.

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