Davante Adams scores hat-trick for Rams
Chiefs demolish Raiders and Eagles see off strong Vikings challenge to move to 5-2 in early games
Packers, Broncos & Cowboys in action from 21:00 BST
Listen Live to Colts @ Chargers on BBC Radio 5 Sports Extra from 21:00 BST
Miami Dolphins 0-3 Cleveland Browns
The Browns generate just enough offence, albeit with a big penalty in there, to get close enough for Andre Szmyt to drill a 30-yard field goal to go ahead.
It's tough going in this one though.
New England Patriots 3-10 Tennessee Titans
Cam Ward sends a 38-yard pass to a running Chimere Dike at deep left, who gets his first NFL touchdown.
Joey Slye converts the extra point.
Will the Pats answer back again?
Carolina Panthers 3-0 New York Jets
Nearly at the end of the first quarter and barely 60 yards of passing combined between these two quarterbacks.
Ryan Fitzgerald's 30-yard field goal puts Carolina on the board first.
Miami Dolphins 0-0 Cleveland Browns
Almost a quarter gone and the two QBs in this game, Dillon Gabriel and Tua Tagovailoa have combined for four completed and 30 yards.
Sums the game up so far...
Philadelphia Eagles 7–3 Minnesota Vikings
Shocker for Minnesota Vikings as they lose 32 yards from a busted snap on third down.
Quarterback Carson Wentz manages to scramble back and retrieve it but they'll have to settle for a field goal.
Duly buried from 59 yards by Will Reichard.
New England Patriots @ Tennessee Titans
The Patriots look to answer back. Drake Maye is sacked twice but they are able to set up Andy Borregales who converts his 36-yard kick.
Las Vegas Raiders 0–7 Kansas City Chiefs
Welcome back to the NFL, Rashee Rice.
An ACL injury at the start of last season wrecked 2024 for the Chiefs receiver and then he faced a six-game suspension to begin this year.
Like he's never been away as Patrick Mahomes shovels it off to him and in he runs.
New Orleans Saints 0-3 Chicago Bears
The Bears get on the board first with a Jake Moody field goal from 27 yards out.
Moody is a great story, cut by the 49ers after missing field goals at the start of the year, then only elevated to the Bears squad days before their win against Washington last week.
Which Moody claimed with a field goal as time expired!
Fun Fact: The Bears have won both of their last two games 25-24.
Las Vegas Raiders 0–0 Kansas City Chiefs
Who else for Kansas City Chiefs but Travis Kelce.
The giant tight end has open field in front of him as Patrick Mahomes picks him out for a 44-yard run.
Home team on the move.
New England Patriots 0-3 Tennessee Titans
The Titans get their first points on the board with interim head coach Mike McCoy.
The Patriots didn't make it easy for them on the opening play of the game, two tackles by Marcus Jones slows their attack but Joey Slye is able to convert the 49-yard kick in the end.
Philadelphia Eagles 7–0 Minnesota Vikings
It's not Saquon Barkley that sees it in for the Eagles but rather AJ Brown who is on the end of Jalen Hurts' 37-yard touchdown pass.
Ideal start for a team that was heavily criticised after last week's beating by the New York Giants.
Philadelphia Eagles 0–0 Minnesota Vikings
Ten plays in this opening drive for Jalen Hurts and the Philadelphia Eagles but they've only gone 30 yards.
This offence is yet to ignite this season but they've started with a reasonable ploy.
Give it to Saquon Barkley.
Los Angeles Rams @ Jacksonville Jaguars (14:30 BST)
Could the NFL draft number one pick be cursed?
The Jags' 2021 win over Miami at Tottenham eased the pressure on head coach Urban Meyer as it was also his first win in the NFL.
But it only delayed the inevitable as the Jags claimed just one more win before Meyer was sacked 13 games into Trevor Lawrence's season, adding to the list of coaches to be fired after their team had claimed that year's number one draft pick.
With Brian Callahan having just suffered the same fate at Tennessee, could it really be a curse?
Thumbs up if you think it is.
Maybe it's just a natural result of dumping a rookie quarterback into the worst team in the NFL from the previous season....
Philadelphia Eagles @ Minnesota Vikings (18:00 BST)
Image source, Getty ImagesBack-to-back defeats for the champs means the Eagles travel to Minnesota with plenty of question marks over them - but that's not exactly the first time under Nick Sirianni.
The manner of the defeat to the Giants was more of a concern than the actual result though, especially the offence where things are just not clicking - Jalen Hurts seems disconnected with his receivers and they're struggling to get Saquon Barkley cooking.
Philly's third-worst offence in in total yards facing Minnesota's defence allowing the second fewest will be the decider in this game.
As will Carson Wentz and how he plays against his former team...
Los Angeles Rams 35-7 Jacksonville Jaguars
Image source, Getty ImagesImpressive demolition of the Jaguars there by Matthew Stafford and the Rams.
They move to 5-2 and top the NFC West from the 49ers and Seahawks (both 4-2).
Are they primed for a run at the Super Bowl this season?
Read Ben Collins' report from Wembley Stadium.
New Orleans Saints @ Chicago Bears
Image source, Getty ImagesAmazingly, the Chicago Bears have won their last two games by the exact same 25-24 scoreline. That's the only thing more surprising them then stringing three straights wins together after a shaky start to the season.
Ben Johnson looks to be getting Caleb Williams comfortable running his offence and after what he did with Detroit's attack the Bears fans have every right to be hopeful of them pushing on from here.
And at home to the 1-5 Saints looks a decent tie to maintain their winning run, with New Orleans getting beaten at home by the Patriots last week.
Las Vegas Raiders @ Kansas City Chiefs (18:00 BST)
Image source, Getty ImagesVegas ended a four-game losing streak last week, but it was against the Titans, and they've a rotten recent run against their divisional rivals, losing nine of the past 10 and 14 of 16.
And the Chiefs could just be turning the corner going by their much improved performance in a comprehensive win of the talented Detroit Lions last week.
Patrick Mahomes looked sharp with more confidence in receivers suchs as Xavier Worthy, Hollywood Brown and JuJu Smith-Schuster - and this week he gets Rashee Rice back from suspension.
Things look to be heading in the right direction in KC.
Carolina Panthers @ New York Jets (18:00 BST)
Image source, Getty ImagesDon't look now, but the Carolina Panthers are on a roll! They've won two in a row now to improve to 3-3 for the season, so a visit to the 0-6 Jets shouldn't be too much of a worry.
The Panthers look to slowly be turning things around with Bryce Young at quarterback, as they look to end a seven-year play-off drought that's the second longest in the league.
The Jets though have spent twice as long on the outside looking in on the play-offs, and a loss here would drop them to 0-7 for just the third time in team history, but the second in five years.
New England Patriots @ Tennessee Titans (18:00 BST)
'The learning curve was too much'
This game was supposed to be about former Titans head coach Mike Vrabel returning to Tennessee, but instead it's about the Titans firing their head coach Brian Callahan after a poor start to the season.
Callahan went 1-5 after the team drafted Cam Ward with the first pick of the draft, and the team obviously didn't see enough potential to improve.
Things may not improve tonight either against the 4-2 Patriots who are riding a three-game winning streak with Drake Maye playing great in his second season.
Miami Dolphins @ Cleveland Browns
Image source, Getty ImagesA match-up between two 1-5 teams may not be the most promising on the slate but bear with us.
Dire on offense but dominant in defence, the Browns are a tough nut to crack at home. Expect last season's Defensive Player of the Year Myles Garrett and company to apply significant pressure to this Dolphins offense.
Last week, quarterback Tua Tagovailoa almost led Miami to a fourth quarter comeback win over the Los Angeles Chargers only to fall short.
He'll need to be on top form to get any joy in Cleveland.